Professor | Qiang Huang | Asia Growth Partners

Name	Qiang Huang
Contact Information	huangqiang@fudan.edu.cn
Language ability	Chinese, English, German
Province	Shanghai

Name

Qiang Huang

Contact Information

huangqiang@fudan.edu.cn

Language ability

Chinese, English, German

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Life Sciences
Academic Background & Achievements	1991 - Bachelor's Degree in Chemistry: Zhejiang University 1994 - Master's Degree in Physical Chemistry: Zhejiang University 1998 - Ph.D. in Physical Chemistry: Zhejiang University 1999-2000 - Postdoctoral Research in Molecular Biophysics: Humboldt University of Berlin 2001-2003 - Research in Molecular Biophysics: Humboldt University of Berlin and National Sun Yat-sen University 2004 - Joined Fudan University, School of Life Sciences Published nearly 90 academic papers Received nearly 20 authorized invention patents
Work Experience	2004-present - Fudan University - Professor 2005-present - Fudan University - Doctoral Supervisor
Awards	Golden Bridge Award (Second Contributor): China Technology Market Association Second Prize for Technological Invention: Ministry of Education Second Prize for Technological Invention: Shanghai

University/Lab Affiliation and Title

Fudan University

Faculty

Life Sciences

Academic Background & Achievements

1991 - Bachelor's Degree in Chemistry: Zhejiang University
1994 - Master's Degree in Physical Chemistry: Zhejiang University
1998 - Ph.D. in Physical Chemistry: Zhejiang University
1999-2000 - Postdoctoral Research in Molecular Biophysics: Humboldt University of Berlin
2001-2003 - Research in Molecular Biophysics: Humboldt University of Berlin and National Sun Yat-sen University
2004 - Joined Fudan University, School of Life Sciences
Published nearly 90 academic papers
Received nearly 20 authorized invention patents

Work Experience

2004-present - Fudan University - Professor
2005-present - Fudan University - Doctoral Supervisor

Awards

Golden Bridge Award (Second Contributor): China Technology Market Association
Second Prize for Technological Invention: Ministry of Education
Second Prize for Technological Invention: Shanghai

Areas of Focus	Design and optimization of biological macromolecules Mechanism and regulation of gene editing systems Artificial intelligence design technology for proteins
Publications	Computational design and engineering of self-assembling multivalent microproteins with therapeutic potential against SARS-CoV-2, Q. Qin, X. Jiang, L. Huo, J. Qian, H. Yu, H. Zhu, W. Du, Y. Cao, X. Zhang, Q. Huang, 2024 Structure-guided design of a trivalent nanobody cluster targeting SARS-CoV-2 spike protein, X. Jiang, Q. Qin, H. Zhu, J. Qian, Q. Huang, 2024 De novo design of DNA aptamers that target okadaic acid (OA) by docking-then-assembling of single nucleotides, M. Song, Y. Li, R. Gao, J. Liu, Q. Huang, 2022 Deep-learning with synthetic data enables automated picking of cryo-EM particle images of biological macromolecules, R. Yao, J. Qian, Q. Huang, 2020 Surface binding energy landscapes affect phosphodiesterase isoform-specific inhibitor selectivity, Q. Liu, A. Herrmann, Q. Huang, 2019 Structural insights into DNA cleavage activation of CRISPR-Cas9 system, C. Huai, G. Li, R. Yao, Y. Zhang, M. Cao, L. Kong, C. Jia, H. Yuan, H. Chen, D. Lu, Q. Huang, 2017 X-ray crystal structure of phosphodiesterase 2 in complex with a highly selective, nanomolar inhibitor reveals a binding-induced pocket important for selectivity, J. Zhu, Q. Yang, D. Dai, Q. Huang, 2013 Calculating pH-dependent free energy of proteins by using Monte Carlo protonation probabilities of ionizable residues, Q. Huang, A. Herrmann, 2012 Bilayer conformation of fusion peptide of influenza virus hemagglutinin: a molecular dynamics simulation study, Q. Huang, C.-L. Chen, A. Herrmann, 2004 Protonation and stability of the globular domain of influenza virus hemagglutinin, Q. Huang, R. Opitz, E.-W. Knapp, A. Herrmann, 2002

Areas of Focus

Design and optimization of biological macromolecules
Mechanism and regulation of gene editing systems
Artificial intelligence design technology for proteins

Publications

Computational design and engineering of self-assembling multivalent microproteins with therapeutic potential against SARS-CoV-2, Q. Qin, X. Jiang, L. Huo, J. Qian, H. Yu, H. Zhu, W. Du, Y. Cao, X. Zhang, Q. Huang, 2024
Structure-guided design of a trivalent nanobody cluster targeting SARS-CoV-2 spike protein, X. Jiang, Q. Qin, H. Zhu, J. Qian, Q. Huang, 2024
De novo design of DNA aptamers that target okadaic acid (OA) by docking-then-assembling of single nucleotides, M. Song, Y. Li, R. Gao, J. Liu, Q. Huang, 2022
Deep-learning with synthetic data enables automated picking of cryo-EM particle images of biological macromolecules, R. Yao, J. Qian, Q. Huang, 2020
Surface binding energy landscapes affect phosphodiesterase isoform-specific inhibitor selectivity, Q. Liu, A. Herrmann, Q. Huang, 2019
Structural insights into DNA cleavage activation of CRISPR-Cas9 system, C. Huai, G. Li, R. Yao, Y. Zhang, M. Cao, L. Kong, C. Jia, H. Yuan, H. Chen, D. Lu, Q. Huang, 2017
X-ray crystal structure of phosphodiesterase 2 in complex with a highly selective, nanomolar inhibitor reveals a binding-induced pocket important for selectivity, J. Zhu, Q. Yang, D. Dai, Q. Huang, 2013
Calculating pH-dependent free energy of proteins by using Monte Carlo protonation probabilities of ionizable residues, Q. Huang, A. Herrmann, 2012
Bilayer conformation of fusion peptide of influenza virus hemagglutinin: a molecular dynamics simulation study, Q. Huang, C.-L. Chen, A. Herrmann, 2004
Protonation and stability of the globular domain of influenza virus hemagglutinin, Q. Huang, R. Opitz, E.-W. Knapp, A. Herrmann, 2002

Biological Macromolecules Design Optimization Gene Editing Mechanism Regulation Artificial Intelligence Protein Design Molecular Modeling Computational Simulation

Guohui Chuai - Tongji University

Yudong Cai - Shanghai University

Yudong Cai - Shanghai University

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