Professor | Jinzhong Lin | Asia Growth Partners

Name	Jinzhong Lin
Contact Information	linjinzhong@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

Name

Jinzhong Lin

Contact Information

linjinzhong@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Life Sciences
Academic Background & Achievements	2001 Bachelor's Degree: China Agricultural University 2008 PhD: Institute of Biophysics, Chinese Academy of Sciences 2008-2011 Postdoctoral Research: Beijing Institute of Life Sciences 2011-2016 Research: Yale University 2015-2016 Research Specialist: Howard Hughes Medical Institute 2017 Joined Fudan University
Work Experience	2008-2011 - Beijing Institute of Life Sciences - Postdoctoral Research 2011-2016 - Yale University - Research 2015-2016 - Howard Hughes Medical Institute - Research Specialist 2017-Present - Fudan University - Researcher, Doctoral Supervisor, PI of National Key Laboratory of Genetic Engineering
Awards	Blavatnik Young Scientist Award (2015): New York Academy of Sciences Director's Paper Award (2007): Institute of Biophysics, Chinese Academy of Sciences Tan Jiazhen Foundation Jiuyuan Scholarship (2007) Tan Jiazhen Life Science Scholarship First Prize (1997)

University/Lab Affiliation and Title

Fudan University

Faculty

Life Sciences

Academic Background & Achievements

2001 Bachelor's Degree: China Agricultural University
2008 PhD: Institute of Biophysics, Chinese Academy of Sciences
2008-2011 Postdoctoral Research: Beijing Institute of Life Sciences
2011-2016 Research: Yale University
2015-2016 Research Specialist: Howard Hughes Medical Institute
2017 Joined Fudan University

Work Experience

2008-2011 - Beijing Institute of Life Sciences - Postdoctoral Research
2011-2016 - Yale University - Research
2015-2016 - Howard Hughes Medical Institute - Research Specialist
2017-Present - Fudan University - Researcher, Doctoral Supervisor, PI of National Key Laboratory of Genetic Engineering

Awards

Blavatnik Young Scientist Award (2015): New York Academy of Sciences
Director's Paper Award (2007): Institute of Biophysics, Chinese Academy of Sciences
Tan Jiazhen Foundation Jiuyuan Scholarship (2007)
Tan Jiazhen Life Science Scholarship First Prize (1997)

Areas of Focus	Molecular Mechanisms of Gene Translation and Regulation Mechanisms of Action and Resistance of Ribosome-Targeting Antibiotics
Publications	Box C/D guide RNAs recognize maximal ten bases of substrates, Yangm, Z, Lin J., Ye K., 2016 Integrative structural analysis of the UTPB complex, an early assembly factor for eukaryotic small ribosomal subunits, Zhang, C., Sun, Q., Chen, R., Chen, X., Lin, J., and Ye, K., 2016 Elongation Factor 4 Remodels the A-site tRNA on the Ribosome, Gagnon, M. G., Lin, J., Steitz, T. A., 2016 Conformational Changes of Elongation Factor G on the Ribosome During tRNA Translocation, Lin, J., Gagnon, M. G., Bulkley, D. & Steitz, T. A., 2015 Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome, Gagnon, M. G., Lin, J., Bulkley, D. & Steitz, T. A., 2014 Structure of Utp21 tandem WD domain provides insight into the organization of the UTPB complex involved in ribosome synthesis, Zhang, C., Lin, J., Liu, W. et al., 2014 An RNA-binding complex involved in ribosome biogenesis contains a protein with homology to tRNA CCA-adding enzyme, Lin, J., Lu, J., Feng, Y., Sun, M. & Ye, K., 2013 Structure of the PolIIIalpha-tauc-DNA complex suggests an atomic model of the replisome, Liu, B., Lin, J. & Steitz, T. A., 2013 Structural and functional analysis of the U3 snoRNA binding protein Rrp9, Zhang, L., Lin, J. & Ye, K., 2013 Initiation factor 2 crystal structure reveals a different domain organization from eukaryotic initiation factor 5B and mechanism among translational GTPases, Eiler, D., Lin, J., Simonetti, A., Klaholz, B. P. & Steitz, T. A., 2013 Identification of cross-linked peptides from complex samples, Yang, B., Wu, YJ., Zhu, M., Fan SB, Lin, J., Zhang, K., et al., 2012 Potential key bases of ribosomal RNA to kingdom-specific spectra of antibiotic susceptibility and the possible archaeal origin of eukaryotes, Xie, Q., Wang, Y., Lin, J., Qin, Y., Wang, Y., Bu, W., 2012 Structural basis for site-specific ribose methylation by box C/D RNA protein complexes, Lin, J., Lai, S., Jia, R. et al., 2011 Solution structure of the human HSPC280 protein, Lin, J., Zhou, T. & Wang, J., 2011 Structure and molecular evolution of CDGSH iron-sulfur domains, Lin, J., Zhang, L., Lai, S. & Ye, K., 2011 Structural diversity of eukaryotic 18S rRNA and its impact on alignment and phylogenetic reconstruction, Xie, Q., Lin, J., Qin, Y., Zhou, J. & Bu, W., 2011 Structure of the autocatalytic cysteine protease domain of potyvirus helper-component proteinase, Guo, B., Lin, J. & Ye, K., 2011 Binding of reduced nicotinamide adenine dinucleotide phosphate destabilizes the iron-sulfur clusters of human mitoNEET, Zhou, T., Lin, J., Feng, Y. & Wang, J., 2010 Structural organization of box C/D RNA-guided RNA methyltransferase, Ye, K., Jia, R., Lin, J. et al., 2009 Crystal structure of human mitoNEET reveals distinct groups of iron sulfur proteins, Lin, J., Zhou, T., Ye, K. & Wang, J., 2007

Areas of Focus

Molecular Mechanisms of Gene Translation and Regulation
Mechanisms of Action and Resistance of Ribosome-Targeting Antibiotics

Publications

Box C/D guide RNAs recognize maximal ten bases of substrates, Yangm, Z, Lin J., Ye K., 2016
Integrative structural analysis of the UTPB complex, an early assembly factor for eukaryotic small ribosomal subunits, Zhang, C., Sun, Q., Chen, R., Chen, X., Lin, J., and Ye, K., 2016
Elongation Factor 4 Remodels the A-site tRNA on the Ribosome, Gagnon, M. G.*, Lin, J.*, Steitz, T. A., 2016
Conformational Changes of Elongation Factor G on the Ribosome During tRNA Translocation, Lin, J.*, Gagnon, M. G.*, Bulkley, D. & Steitz, T. A., 2015
Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome, Gagnon, M. G.*, Lin, J.*, Bulkley, D. & Steitz, T. A., 2014
Structure of Utp21 tandem WD domain provides insight into the organization of the UTPB complex involved in ribosome synthesis, Zhang, C., Lin, J., Liu, W. et al., 2014
An RNA-binding complex involved in ribosome biogenesis contains a protein with homology to tRNA CCA-adding enzyme, Lin, J.*, Lu, J.*, Feng, Y., Sun, M. & Ye, K., 2013
Structure of the PolIIIalpha-tauc-DNA complex suggests an atomic model of the replisome, Liu, B., Lin, J. & Steitz, T. A., 2013
Structural and functional analysis of the U3 snoRNA binding protein Rrp9, Zhang, L., Lin, J. & Ye, K., 2013
Initiation factor 2 crystal structure reveals a different domain organization from eukaryotic initiation factor 5B and mechanism among translational GTPases, Eiler, D., Lin, J., Simonetti, A., Klaholz, B. P. & Steitz, T. A., 2013
Identification of cross-linked peptides from complex samples, Yang, B., Wu, YJ., Zhu, M., Fan SB, Lin, J., Zhang, K., et al., 2012
Potential key bases of ribosomal RNA to kingdom-specific spectra of antibiotic susceptibility and the possible archaeal origin of eukaryotes, Xie, Q., Wang, Y., Lin, J., Qin, Y., Wang, Y., Bu, W., 2012
Structural basis for site-specific ribose methylation by box C/D RNA protein complexes, Lin, J., Lai, S., Jia, R. et al., 2011
Solution structure of the human HSPC280 protein, Lin, J., Zhou, T. & Wang, J., 2011
Structure and molecular evolution of CDGSH iron-sulfur domains, Lin, J.*, Zhang, L.*, Lai, S. & Ye, K., 2011
Structural diversity of eukaryotic 18S rRNA and its impact on alignment and phylogenetic reconstruction, Xie, Q., Lin, J., Qin, Y., Zhou, J. & Bu, W., 2011
Structure of the autocatalytic cysteine protease domain of potyvirus helper-component proteinase, Guo, B., Lin, J. & Ye, K., 2011
Binding of reduced nicotinamide adenine dinucleotide phosphate destabilizes the iron-sulfur clusters of human mitoNEET, Zhou, T., Lin, J., Feng, Y. & Wang, J., 2010
Structural organization of box C/D RNA-guided RNA methyltransferase, Ye, K., Jia, R., Lin, J. et al., 2009
Crystal structure of human mitoNEET reveals distinct groups of iron sulfur proteins, Lin, J., Zhou, T., Ye, K. & Wang, J., 2007

Gene Translation Regulation Mrna Protein Synthesis Eukaryotic System Translation Initiation Non-Coding Region Oncogenes Structural Biology Molecular Biology

Hua Gu - Tongji University

Xiaofeng Cai - Shanghai Normal University

Xiaobin Wu - Shanghai Normal University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us