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Boxun Lu
Life Science
Fudan University
Shanghai
Language: Chinese, English
Neurodegenerative Diseases
Drug Development
Biophysics
Chemical Biology
Huntington'S Disease
Htt Protein
Gpr52
Mapk11
Hipk3
Autophagy
Areas of Focus
- Neurodegenerative Diseases
- Original Drug Development Strategies
Academic Background & Achievements
- Bachelor's Degree: Fudan University
- Ph.D.: University of Pennsylvania
- National Distinguished Youth Fund
- National Excellent Youth Fund
- National Original Project Fund
- Newton Advanced Fellowship from the British Academy of Medical Sciences
- Xplorer Prize
- Ministry of Education Youth Science Award
- Wu Rui Memorial Foundation Gu Xiaocheng Award
- Shanghai Youth Science and Technology Talent
Publications
- Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds, Li Z, et.al, Ding Y*, Fei Y*, Lu B*, 2019
- Targeting Gpr52 lowers mutant HTT levels and rescues Huntington’s disease-associated phenotypes, Song H, et.al, Lu B, 2018
- Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington’s disease models, Yu M, Fu Y, Liang Y, et.al, Lu B, 2017
- A Toxic Mutant Huntingtin Species Is Resistant to Selective Autophagy, Fu Y, Wu P, Pan Y, Sun X, Difiglia M, Lu B, 2017
- A Striatal-enriched Intronic GPCR Modulates Huntingtin Levels and Toxicity, Yao Y, Cui X, Al-Ramah I, Sun X, Li B, Hou J, Difiglia M, Palacino J, Wu Z, Ma L, Botas J, Boxun Lu, 2015
Awards
- Xplorer Prize
- Ministry of Education Youth Science Award
- Wu Rui Memorial Foundation Gu Xiaocheng Award
- Shanghai Youth Science and Technology Talent
