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Huiru Tang
Life Science
Fudan University
Shanghai
Language: English, Chinese
Metabolomics
High-Throughput
Ultra-Sensitive
Integration
Transcriptomics
Proteomics
Microbiomics
Molecular Basis
Major Diseases
Data Analysis
Areas of Focus
- Metabolomics
- High-throughput and ultra-sensitive metabolomics
- Integration of metabolomics with transcriptomics/proteomics/microbiomics
- Molecular basis of major diseases
Work Experience
- 1992-2005 - Senior Scientist at BBSRC Food Research Institute and Imperial College London
- 2005-2014 - Researcher, Doctoral Supervisor, Deputy Director of Research Department at Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences
- 2014-present - Professor at School of Life Sciences, Fudan University
Academic Background & Achievements
- 1986 - Bachelor's Degree: Northwest University of Light Industry (now Shaanxi University of Science and Technology)
- 1994 - PhD: University of London
- Fellow of the Royal Society of Chemistry
- Published over 210 SCI papers with more than 12,000 citations (h-index ~63)
- Awarded 6 invention patents
Publications
- Anopheline mosquitoes are protected against parasite infection by tryptophan catabolism in gut microbiota, Y. B. Feng, et al, 2022
- Inhibiting 3bHSD1 to eliminate the oncogenic effects of progesterone in prostate cancer, Z. M. Hou, et al, 2022
- Simultaneous quantification of 70 elements in biofluids within 5 min using inductively coupled plasma mass spectrometry to reveal elementomic phenotypes of healthy Chinese adults, J. H. Liu, et al, 2022
- Quantitative structure-retention relationship for reliable metabolite identification and quantification in metabolomics using ion-pair reversed-phase chromatography coupled with tandem mass spectrometry, Q. Y. Hu, et al, 2022
- NAFLD-related gene polymorphisms and all-cause and cause-specific mortality in an Asian population: the Shanghai Changfeng Study, M. F. Xia, et al, 2022
- Insights into contribution of genetic variants towards the susceptibility of MAFLD revealed by the NMR_based lipoprotein profiling, M. F. Xia, et al, 2021
- Asparagine reinforces mTORC1 signaling to boost thermogenesis and glycolysis in adipose tissues, Y. Xu, et al, 2021
- Glucose-mediated proliferation of a gut commensal bacterium promotes Plasmodiuminfection by increasing mosquito midgut pH, M. Wang, et al, 2021
- A feasibility study of metabolic phenotyping of dried blood spot specimens in rural Chinese women exposed to household air pollution, R. Loo, et al, 2021
- Development and validation of an improved probabilistic quotient normalization method for LC/MS- and NMR-based metabonomic analysis, Y. P. An, et al, 2020
- A vitamin-C-derived DNA modification catalysed by an algal TET homologue, J. Xue, et al, 2019
- Alterations of bile acids and gut microbiota in obesity induced by high fat diet in rat model, H. Lin, et al, 2019
- Discovery of a non-stereoselective cytochrome P450 catalyzing either 8α- or 8β-hydroxylation of germacrene A acid from the Chinese medicinal plant, Inula hupehensis, J. Gou, et al, 2018
- Combined metabonomic and quantitative RT-PCR analyses revealed metabolic reprogramming associated with Fusarium graminearum resistance in transgenic Arabidopsis thaliana, F. Chen, et al, 2018
- Metabolomics reveals that dietary ferulic acid and quercetin modulate metabolic homeostasis in rats, L. Zhang, et al, 2018
- Dynamic metabolic responses of brown planthoppers towards susceptible and resistant rice plants, C. Liu, et al, 2017
- Quantitative 13C traces of glucose fate in hepatitis B virus infected hepatocytes, Q. Wan, et al, 2017
- Decreased glutathione biosynthesis contributes to EGFR T790M-driven erlotinib resistance in non-small cell lung cancer, H. Li, et al, 2016
- cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions, L. Sun, et al, 2015
- Human symbiotic gut microbes specifically modulate metabolic phenotypes, M. Li, et al, 2008
Awards
- Fellow of the Royal Society of Chemistry (2005)
- National Science Fund for Distinguished Young Scholars (2008)
- National Candidate of the New Century Talents Project (2009)
- Wang Tianjuan Spectroscopy Award (2010)
- Outstanding Scientific Worker of Wuhan (2011)
