Areas of Focus
- 代谢组学
- 高通量超灵敏代谢组学
- 代谢组与转录组/蛋白质组/微生物组数据整合分析
- 重大疾病的分子基础
Work Experience
- 1992-2005 - 英国BBSRC食品研究所和帝国理工学院生物医学部高级科学家
- 2005-2014 - 中科院武汉物数所研究员、博导、研究部副主任
- 2014-至今 - 复旦大学生命科学学院教授
Academic Background & Achievements
- 1986 - 学士学位: 西北轻工业学院(现陕西科技大学)
- 1994 - 博士学位: 伦敦大学
- 英国皇家化学会会士
- 发表SCI论文210余篇,被引1.2万余次(h指数~63)
- 获批发明专利6项
Publications
- Anopheline mosquitoes are protected against parasite infection by tryptophan catabolism in gut microbiota, Y. B. Feng, et al, 2022
- Inhibiting 3bHSD1 to eliminate the oncogenic effects of progesterone in prostate cancer, Z. M. Hou, et al, 2022
- Simultaneous quantification of 70 elements in biofluids within 5 min using inductively coupled plasma mass spectrometry to reveal elementomic phenotypes of healthy Chinese adults, J. H. Liu, et al, 2022
- Quantitative structure-retention relationship for reliable metabolite identification and quantification in metabolomics using ion-pair reversed-phase chromatography coupled with tandem mass spectrometry, Q. Y. Hu, et al, 2022
- NAFLD-related gene polymorphisms and all-cause and cause-specific mortality in an Asian population: the Shanghai Changfeng Study, M. F. Xia, et al, 2022
- Insights into contribution of genetic variants towards the susceptibility of MAFLD revealed by the NMR_based lipoprotein profiling, M. F. Xia, et al, 2021
- Asparagine reinforces mTORC1 signaling to boost thermogenesis and glycolysis in adipose tissues, Y. Xu, et al, 2021
- Glucose-mediated proliferation of a gut commensal bacterium promotes Plasmodiuminfection by increasing mosquito midgut pH, M. Wang, et al, 2021
- A feasibility study of metabolic phenotyping of dried blood spot specimens in rural Chinese women exposed to household air pollution, R. Loo, et al, 2021
- Development and validation of an improved probabilistic quotient normalization method for LC/MS- and NMR-based metabonomic analysis, Y. P. An, et al, 2020
- A vitamin-C-derived DNA modification catalysed by an algal TET homologue, J. Xue, et al, 2019
- Alterations of bile acids and gut microbiota in obesity induced by high fat diet in rat model, H. Lin, et al, 2019
- Discovery of a non-stereoselective cytochrome P450 catalyzing either 8α- or 8β-hydroxylation of germacrene A acid from the Chinese medicinal plant, Inula hupehensis, J. Gou, et al, 2018
- Combined metabonomic and quantitative RT-PCR analyses revealed metabolic reprogramming associated with Fusarium graminearum resistance in transgenic Arabidopsis thaliana, F. Chen, et al, 2018
- Metabolomics reveals that dietary ferulic acid and quercetin modulate metabolic homeostasis in rats, L. Zhang, et al, 2018
- Dynamic metabolic responses of brown planthoppers towards susceptible and resistant rice plants, C. Liu, et al, 2017
- Quantitative 13C traces of glucose fate in hepatitis B virus infected hepatocytes, Q. Wan, et al, 2017
- Decreased glutathione biosynthesis contributes to EGFR T790M-driven erlotinib resistance in non-small cell lung cancer, H. Li, et al, 2016
- cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions, L. Sun, et al, 2015
- Human symbiotic gut microbes specifically modulate metabolic phenotypes, M. Li, et al, 2008
Awards
- 英国皇家化学会会士(2005)
- 国家杰出青年科学基金(2008)
- 新世纪百千万人才工程国家级人选称号(2009)
- 王天眷波谱学奖(2010)
- 武汉市优秀科技工作者(2011)