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Wenqiang Yu
Life Science
Fudan University
Shanghai
Language: English, Chinese
Non-Coding Rna
Chromatin
Modification
Interaction
Coordination
Epigenetics
Gene Expression
Regulation
Genomics
Biomedical Research
Areas of Focus
- Interaction and coordination of non-coding RNA and chromatin modification
Work Experience
- 2001-2007 - Uppsala University and Johns Hopkins University - Postdoctoral Researcher
- 2007-11 - Columbia University - Faculty and Associate Research Scientist
- Current - Fudan University - PI and Researcher, Deputy Director of Genomics and Epigenomics Research Institute
Academic Background & Achievements
- 1989 Medical Bachelor's Degree: Fourth Military Medical University
- 2001 PhD: Fourth Military Medical University
- Chief Scientist of National '973' Project
- Changjiang Scholar Distinguished Professor
Publications
- Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA, Yu W., Gius D., Onyango P., Muldoon-Jacobs K., Karp J., Feinberg A.P., Cui H., 2008
- Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation, Yu W., Ginjala V., Pant V., Chernukhin I., Whitehead J., Docquier F., Farrar D., Tavoosidana G., Mukhopadhyay R., Kanduri C., Oshimura M., Feinberg A.P., Lobanenkov V., Klenova E., Ohlsson R., 2004
- Intra-individual change over time in DNA methylation with familial clustering, Bjornsson H.T., Sigurdsson M.I., Fallin M.D., Irizarry R.A., Aspelund T., Cui H., Yu W., Rongione M.A., Ekstr m T.J., Harris T.B., Launer L.J., Eiriksdottir G., Leppert M.F., Sapienza C., Gudnason V., Feinberg A.P., 2008
- The binding sites for the chromatin insulator protein CTCF map to DNA methylation-free domains genome-wide, Mukhopadhyay R., Yu W., Whitehead J., Xu J., Lezcano M., Pack S., Kanduri C., Kanduri M., Ginjala V., Vostrov A., Quitschke W., Chernukhin I., Klenova E., Lobanenkov V., Ohlsson R., 2004
- DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation, Sun L., Huang L., Nguyen P., Bisht K.S., Bar-Sela G., Ho A.S., Bradbury C.M., Yu W., Cui H., Lee S., Trepel J.B., Feinberg A.P., Gius D., 2008
- CTCF interacts with and recruits the largest subunit of RNA polymerase II to CTCF target sites genome-wide, Chernukhin I., Shamsuddin S., Kang S.Y., Bergstr m R., Kwon Y.W., Yu W., Whitehead J., Mukhopadhyay R., Docquier F., Farrar D., Morrison I., Vigneron M., Wu S.Y., Chiang C.M., Loukinov D., Lobanenkov V., Ohlsson R., Klenova E., 2007
