Areas of Focus
- Molecular regulation mechanisms, networks, and engineering of antibiotic synthesis in Pseudomonas
- Global regulation networks and metabolic engineering in microbial primary and secondary metabolism
- Application and development of microbial-derived pesticides and other high-value products
Work Experience
- 2005 - Present: Shanghai Jiao Tong University - Associate Professor
Academic Background & Achievements
- 2005 - PhD in Biochemistry and Molecular Biology from Shanghai Jiao Tong University
- Led a project that won the 2007 Shanghai Science and Technology Progress First Prize
Publications
- Lon protease downregulates phenazine-1-carboxamide biosynthesis by degrading the quorum sensing signal synthase PhzI and exhibits negative feedback regulation of Lon itself in Pseudomonas chlororaphis HT66, Zheng Wang, Xianqing Huang, Malik Jan, Deyu Kong, Wei Wang, Xuehong Zhang, 2021
- GacS/GacA activates pyoluteorin biosynthesis through Gac/Rsm-RsmE cascade and RsmA/RsmE-driven feedback loop in Pseudomonas protegens H78, Zheng Wang, Xianqing Huang, Yujie Liu, Guohuan Yang, Yang Liu, Xuehong Zhang, 2017
- The Lon protease negatively regulates pyoluteorin biosynthesis through the Gac/Rsm-RsmE cascade and directly degrades the transcriptional activator PltR in Pseudomonas protegens H78, Zheng Wang, Xianqing Huang, Chenxi Nie, Tao Xiang, Xuehong Zhang, 2022
- The global regulator Hfq exhibits far more extensive and intensive regulation than Crc in Pseudomonas protegens H78, Zheng Wang, Xianqing Huang, Malik Jan, Deyu Kong, Jingwen Pan, Xuehong Zhang, 2021
- The (p)ppGpp-mediated stringent response regulatory system globally inhibits primary metabolism and activates secondary metabolism in Pseudomonas Protegens H78, Lingyu Wu, Zheng Wang, Yejun Guan, Xianqing Huang, Huimin Shi, Yujie Liu, Xuehong Zhang, 2020
- Pleiotropic control of antibiotic biosynthesis, flagellar operon expression, biofilm formation, and carbon source utilization by RpoN in Pseudomonas protegens H78, Yujie Liu, Huimin Shi, Zheng Wang, Xianqing Huang, Xuehong Zhang, 2018
- Improvement of pyoluteorin production in Pseudomonas protegens H78 through engineering its biosynthetic and regulatory pathways, Huimin Shi, Xianqing Huang, Zheng Wang, Yejun Guan, Xuehong Zhang, 2019
- Global control of GacA in secondary metabolism, primary metabolism, secretion systems, and motility in the rhizobacterium Pseudomonas aeruginosa M18, Xue Wei, Xianqing Huang, Lulu Tang, Daqiang Wu, Yuquan Xu, 2013
- The RNA chaperone Hfq regulates antibiotic biosynthesis in the rhizobacterium Pseudomonas aeruginosa M18, Guohao Wang, Xianqing Huang, Sainan Li, Jiaofang Huang, Xue Wei, Yaqian Li, Yuquan Xu, 2012
Awards
- 2007: Shanghai Science and Technology Progress First Prize
