Professor | Xianqing Huang | Asia Growth Partners

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Name	Xianqing Huang
Contact Information	xqhuang66@sjtu.edu.cn
Language ability	Chinese, English
Province	Shanghai

Upload Avatar (500 x 500)

Name

Xianqing Huang

Contact Information

xqhuang66@sjtu.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Life Sciences
Academic Background & Achievements	2005 - PhD in Biochemistry and Molecular Biology from Shanghai Jiao Tong University Led 1 National High-tech R&D Program (863 Program) and 3 National Natural Science Foundation projects
Work Experience	2005 - Present: Shanghai Jiao Tong University - Associate Professor
Awards	2007: First Prize of Shanghai Science and Technology Progress Award for the project 'Development and Application of Shenqinmycin'

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Life Sciences

Academic Background & Achievements

2005 - PhD in Biochemistry and Molecular Biology from Shanghai Jiao Tong University
Led 1 National High-tech R&D Program (863 Program) and 3 National Natural Science Foundation projects

Work Experience

2005 - Present: Shanghai Jiao Tong University - Associate Professor

Awards

2007: First Prize of Shanghai Science and Technology Progress Award for the project 'Development and Application of Shenqinmycin'

Areas of Focus	Molecular regulation mechanisms, networks, and engineering of antibiotic synthesis in Pseudomonas Global regulation networks and metabolic engineering of primary and secondary metabolism in microbes Application and development of microbial-derived pesticides and other high-value products
Publications	Lon protease downregulates phenazine-1-carboxamide biosynthesis by degrading the quorum sensing signal synthase PhzI and exhibits negative feedback regulation of Lon itself in Pseudomonas chlororaphis HT66, Zheng Wang, Xianqing Huang , Malik Jan, Deyu Kong, Wei Wang, Xuehong Zhang , 2021 GacS/GacA activates pyoluteorin biosynthesis through Gac/Rsm-RsmE cascade and RsmA/RsmE-driven feedback loop in Pseudomonas protegens H78, Zheng Wang, Xianqing Huang , Yujie Liu, Guohuan Yang, Yang Liu, Xuehong Zhang, 2017 The Lon protease negatively regulates pyoluteorin biosynthesis through the Gac/Rsm-RsmE cascade and directly degrades the transcriptional activator PltR in Pseudomonas protegens H78, Zheng Wang, Xianqing Huang , Chenxi Nie, Tao Xiang, Xuehong Zhang , 2022 The global regulator Hfq exhibits far more extensive and intensive regulation than Crc in Pseudomonas protegens H78, Zheng Wang, Xianqing Huang , Malik Jan, Deyu Kong, Jingwen Pan, Xuehong Zhang , 2021 The (p)ppGpp-mediated stringent response regulatory system globally inhibits primary metabolism and activates secondary metabolism in Pseudomonas Protegens H78, Lingyu Wu, Zheng Wang, Yejun Guan, Xianqing Huang , Huimin Shi, Yujie Liu, Xuehong Zhang, 2020 Pleiotropic control of antibiotic biosynthesis, flagellar operon expression, biofilm formation, and carbon source utilization by RpoN in Pseudomonas protegens H78, Yujie Liu, Huimin Shi, Zheng Wang, Xianqing Huang, Xuehong Zhang, 2018 Improvement of pyoluteorin production in Pseudomonas protegens H78 through engineering its biosynthetic and regulatory pathways, Huimin Shi, Xianqing Huang, Zheng Wang, Yejun Guan, Xuehong Zhang, 2019 Global control of GacA in secondary metabolism, primary metabolism, secretion systems, and motility in the rhizobacterium Pseudomonas aeruginosa M18, Xue Wei, Xianqing Huang , Lulu Tang, Daqiang Wu, Yuquan Xu , 2013 The RNA chaperone Hfq regulates antibiotic biosynthesis in the rhizobacterium Pseudomonas aeruginosa M18, Guohao Wang, Xianqing Huang , Sainan Li, Jiaofang Huang, Xue Wei, Yaqian Li, Yuquan Xu , 2012

Areas of Focus

Molecular regulation mechanisms, networks, and engineering of antibiotic synthesis in Pseudomonas
Global regulation networks and metabolic engineering of primary and secondary metabolism in microbes
Application and development of microbial-derived pesticides and other high-value products

Publications

Lon protease downregulates phenazine-1-carboxamide biosynthesis by degrading the quorum sensing signal synthase PhzI and exhibits negative feedback regulation of Lon itself in Pseudomonas chlororaphis HT66, Zheng Wang, Xianqing Huang *, Malik Jan, Deyu Kong, Wei Wang, Xuehong Zhang *, 2021
GacS/GacA activates pyoluteorin biosynthesis through Gac/Rsm-RsmE cascade and RsmA/RsmE-driven feedback loop in Pseudomonas protegens H78, Zheng Wang, Xianqing Huang *, Yujie Liu, Guohuan Yang, Yang Liu, Xuehong Zhang, 2017
The Lon protease negatively regulates pyoluteorin biosynthesis through the Gac/Rsm-RsmE cascade and directly degrades the transcriptional activator PltR in Pseudomonas protegens H78, Zheng Wang, Xianqing Huang *, Chenxi Nie, Tao Xiang, Xuehong Zhang *, 2022
The global regulator Hfq exhibits far more extensive and intensive regulation than Crc in Pseudomonas protegens H78, Zheng Wang, Xianqing Huang *, Malik Jan, Deyu Kong, Jingwen Pan, Xuehong Zhang *, 2021
The (p)ppGpp-mediated stringent response regulatory system globally inhibits primary metabolism and activates secondary metabolism in Pseudomonas Protegens H78, Lingyu Wu, Zheng Wang, Yejun Guan, Xianqing Huang *, Huimin Shi, Yujie Liu, Xuehong Zhang, 2020
Pleiotropic control of antibiotic biosynthesis, flagellar operon expression, biofilm formation, and carbon source utilization by RpoN in Pseudomonas protegens H78, Yujie Liu, Huimin Shi, Zheng Wang, Xianqing Huang*, Xuehong Zhang, 2018
Improvement of pyoluteorin production in Pseudomonas protegens H78 through engineering its biosynthetic and regulatory pathways, Huimin Shi, Xianqing Huang*, Zheng Wang, Yejun Guan, Xuehong Zhang, 2019
Global control of GacA in secondary metabolism, primary metabolism, secretion systems, and motility in the rhizobacterium Pseudomonas aeruginosa M18, Xue Wei, Xianqing Huang *, Lulu Tang, Daqiang Wu, Yuquan Xu *, 2013
The RNA chaperone Hfq regulates antibiotic biosynthesis in the rhizobacterium Pseudomonas aeruginosa M18, Guohao Wang, Xianqing Huang *, Sainan Li, Jiaofang Huang, Xue Wei, Yaqian Li, Yuquan Xu *, 2012

Antibiotic Synthesis Pseudomonas Molecular Regulation Metabolic Engineering Global Networks Secondary Metabolism Microbial Pesticides High-Value Products Biotechnology Bioengineering

Xianqing Huang - Shanghai Jiao Tong University

Chenguang Liu - Shanghai Jiao Tong University

Mingfei Jin - East China Normal University

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