Areas of Focus
- Directed biosynthesis of natural products
Work Experience
- 2020.09-present: Professor, School of Life Sciences and Technology / Zhangjiang Advanced Research Institute, Shanghai Jiao Tong University
- 2012.01-2020.08: Professor, School of Pharmacy, Wuhan University
- 2011.01-2011.12: Associate Research Fellow, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
- 2008.11-2010.12: Assistant Research Fellow, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
- 2007.09-2008.10: Postdoctoral Fellow, Department of Chemistry, Massachusetts Institute of Technology, USA
Academic Background & Achievements
- 2002-2007 PhD: Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
- 1998-2002 Bachelor: Department of Chemistry, East China Normal University
Publications
- An unusual aromatase/cyclase programs the formation of the phenyldimethylanthrone framework in anthrabenzoxocinones and fasamycin., Kai Jiang, Xu Chen, Xiaoli Yan, Zixin Deng, Shunkun Luo, Xudong Qu, 2024
- Engineering the substrate specificity of a P450 dimerase enables the collective biosynthesis of heterodimeric tryptophan-containing diketopiperazines., Chenghai Sun, Bao-Di Ma, Guangjun Li, Wenya Tian, Lu Yang, Haidong Peng, Zhi Lin, Zixin Deng, Xu-Dong Kong, Xudong Qu, 2023
- A large conserved family of small-molecule carboxyl methyltransferases identified from microorganisms., Zhi Lin, Zhiwei Hu, Linjun Zhou, Benben Liu, Xiaowei Huang, Zixin Deng, Xudong Qu, 2023
- A chemoenzymatic approach to C14-functionalized steroids., Fuzheng Song, Mengmeng Zheng, Junlin Wang, Huanhuan Liu, Zhi Lin, Bengbeng Liu, Zixin Deng, Qianghui Zhou, Xudong Qu, 2023
- A pair of atypical KAS III homologues with initiation and elongation functions programs the polyketide biosynthesis in asukamycin., Xiaoli Yan, Jun Zhang, Hongqun Tan, Zhihao Liu, Kai Jiang, Wenya Tian, Mengmeng Zheng, Zhi Lin, Zixin Deng, Xudong Qu, 2022
- An atypical acyl-CoA synthetase enables efficient biosynthesis of extender units for engineering a polyketide carbon scaffold., Mengmeng Zheng, Jun Zhang, Wan Zhang, Lu Yang, Xiaoli Yan, Wenya Tian, Zhihao Liu, Zhi Lin, Zixin Deng, Xudong Qu, 2022
- A dual role reductase from phytosterol catabolism enables efficient production of valuable steroid precursors., Haidong Peng, Yaya Wang, Yanan Zhang, Zixing Deng, Zhenghua Tian, Xudong Qu, 2021
- Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric ketopiperazines., Chenghai Sun, Zhenyao Luo (co-first author), Wenlu Zhang, Wenya Tian, Haidong Peng, Zhi Lin, Xiaoli Yan, Yanan Zhang, Zixin Deng, Bostjan Kobe, Xinying Jia, Xudong Qu, 2020
- Efficient biosynthesis of heterodimeric C3-aryl pyrroloindoline alkaloids., Wenya Tian, Chenghai Sun (co-first author), Mei Zheng, Mingjia Yu, Yanan Zhang, Haidong Peng, Dongqing Zhu, Jeffery Harmer, Zixin Deng, Shilu Chen, Mohedi Mobli, Xinying Jia, Xudong Qu, 2018
- Uncovering the formation and selection of benzylmalonyl-CoA from the biosynthesis of splenocin and enterocin reveals a versatile way to introduce amino acids into Polyketide carbon scaffolds., Chengcheng Chang, Rong Huang (co-first author), Yan Yan, Hongmin Ma, Zheng Dai, Benying Zhang, Wen Liu, Zixin Deng, Xudong Qu, 2015
Awards
- 2023: Gold Innovation Project Award, National Technical Standards Innovation Base (Dairy)
- 2023: Leader of Outstanding Young Team, Central Universities
- 2023: Bronze Award, 9th China International Internet Plus College Students Innovation and Entrepreneurship Competition (Shanghai Area, as mentor)
- 2022: Shanghai Outstanding Academic Leader
- 2013: National Natural Science Foundation of China, Outstanding Young Scientist Fund
- 2012: Ministry of Education New Century Excellent Talents Support Plan
- 2012: Luojia Distinguished Professor, Wuhan University
