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Baohui Chen
Medical School
Zhejiang University
Zhejiang
Language: Chinese, English
Crispr
Gene Editing
Live Cell Imaging
Chromatin Interaction
Dna Tagging
Single Cell Analysis
Gene Expression
Pol I Transcription
Gene Activation
Endogenous Gene Regulation
Areas of Focus
- CRISPR Technology Development
- Live Cell Imaging Technology Development
- Nuclear Cell Biology
Work Experience
- 2012-2017 - University of California, San Francisco - Postdoctoral Research
- 2017-Present - Zhejiang University School of Medicine - Researcher
Academic Background & Achievements
- 2006 - Bachelor's Degree: Wuhan University
- 2011 - PhD in Biochemistry and Molecular Biology: Beijing Institute of Life Sciences
- National Talent Program and Zhejiang Outstanding Youth Project Support
Publications
- Optimization of the CRISPR-Cas9 System for Real-Time Tracking of Gene Dynamics in Live Cells, Chen B et al., 2013
- Development of a Multicolor DNA Labeling System for Studying Chromatin Interactions in Live Cells, Chen B et al., 2016
- CRISPR-Tag: A DNA Tagging Technology for Simultaneous Tracking of DNA and Protein Dynamics in Single Cells, Chen B et al., 2018
- Live Cell Visualization of Viral DNA Replication Using CRISPR-Tag, Xu H et al., 2022
- TriTag Technology for Directly Linking Chromatin and Gene Expression Dynamics at the Single-Cell Level, Xu H et al., 2020
- LiveArt Technology for Establishing a Live Cell Reporter System for Pol I Transcription Activity, Fu Y et al., 2022
- Narta Technology for Gene Activation with Higher Efficiency than CRISPRa, Liang Y et al., 2022
- Ribo-On and Ribo-Off Technologies for Switching Endogenous Genes On and Off in Specific Tissues and Time Periods, Fang J et al., 2023
