Professor | Hongyan Qi | Asia Growth Partners

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Name	Hongyan Qi
Contact Information	qihongyan@zju.edu.cn
Language ability	Chinese, Italian
Province	Zhejiang

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Name

Hongyan Qi

Contact Information

qihongyan@zju.edu.cn

Language ability

Chinese, Italian

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	2004 - Master's Degree in Pharmacy: University of Calabria, Italy 2008 - PhD in Molecular Biology and Oncology: University of Calabria, Italy Received national scholarship for studying abroad Participated in multiple projects funded by Italian National Science Foundation and Health Foundation (MURST) and Italian Cancer Research Association (AIRC)
Work Experience	2011-present - Zhejiang University School of Medicine - Researcher in Pathology and Pathophysiology
Awards	National Scholarship for studying abroad

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

2004 - Master's Degree in Pharmacy: University of Calabria, Italy
2008 - PhD in Molecular Biology and Oncology: University of Calabria, Italy
Received national scholarship for studying abroad
Participated in multiple projects funded by Italian National Science Foundation and Health Foundation (MURST) and Italian Cancer Research Association (AIRC)

Work Experience

2011-present - Zhejiang University School of Medicine - Researcher in Pathology and Pathophysiology

Awards

National Scholarship for studying abroad

Areas of Focus	Molecular regulatory mechanisms of genomic instability induced by chemical carcinogens and its role in cell malignant transformation and tumorigenesis Post-translational modifications of key transcription factors and their signaling pathway transduction abnormalities in relation to tumorigenesis and development
Publications	Physical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy, Hongyan Qi, 2018 ATR-CHK1-E2F3 signaling transactivates human ribonucleotide reductase small subunit M2 for DNA repair induced by the chemical carcinogen MNNG, Hongyan Qi, 2017 Biphasic reduction of histone H3 phosphorylation in response to N-nitroso compounds induced DNA damage, Hongyan Qi, 2016 Phosphorylation of the alpha-subunit of the eukaryotic initiation factor-2 (eIF2 alpha) alleviates benzo[a]pyrene-7,8-diol-9,10-epoxide induced cell cycle arrest and apoptosis in human cells, Hongyan Qi, 2015 Interferon Regulatory Factor 1 Transactivates Expression of Human DNA Polymerase eta in Response to Carcinogen N-Methyl-N ''-nitro-N-nitrosoguanidine, Hongyan Qi, 2014 Identification and functional implication of nuclear localization signals in the N-terminal domain of JMJD5, Hongyan Qi, 2013 JMJD5 interacts with p53 and negatively regulates p53 function in control of cell cycle and proliferation, Hongyan Qi, 2012 Non-enzymatic action of RRM1 protein upregulates PTEN leading to inhibition of colorectal cancer metastasis, Hongyan Qi, 2011

Areas of Focus

Molecular regulatory mechanisms of genomic instability induced by chemical carcinogens and its role in cell malignant transformation and tumorigenesis
Post-translational modifications of key transcription factors and their signaling pathway transduction abnormalities in relation to tumorigenesis and development

Publications

Physical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy, Hongyan Qi, 2018
ATR-CHK1-E2F3 signaling transactivates human ribonucleotide reductase small subunit M2 for DNA repair induced by the chemical carcinogen MNNG, Hongyan Qi, 2017
Biphasic reduction of histone H3 phosphorylation in response to N-nitroso compounds induced DNA damage, Hongyan Qi, 2016
Phosphorylation of the alpha-subunit of the eukaryotic initiation factor-2 (eIF2 alpha) alleviates benzo[a]pyrene-7,8-diol-9,10-epoxide induced cell cycle arrest and apoptosis in human cells, Hongyan Qi, 2015
Interferon Regulatory Factor 1 Transactivates Expression of Human DNA Polymerase eta in Response to Carcinogen N-Methyl-N ''-nitro-N-nitrosoguanidine, Hongyan Qi, 2014
Identification and functional implication of nuclear localization signals in the N-terminal domain of JMJD5, Hongyan Qi, 2013
JMJD5 interacts with p53 and negatively regulates p53 function in control of cell cycle and proliferation, Hongyan Qi, 2012
Non-enzymatic action of RRM1 protein upregulates PTEN leading to inhibition of colorectal cancer metastasis, Hongyan Qi, 2011

Genomic Instability Chemical Carcinogens Malignant Transformation Tumorigenesis Molecular Regulation Transcription Factors Post-Translational Modifications Signaling Pathways Cell Biology Cancer Research

Jingjing Wu - Zhejiang University

Yi Sun - Zhejiang University

Xiangwei Gao - Zhejiang University

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