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Hongyan Qi
Medical School
Zhejiang University
Zhejiang
Language: Chinese, Italian
Genomic Instability
Chemical Carcinogens
Malignant Transformation
Tumorigenesis
Molecular Regulation
Transcription Factors
Post-Translational Modifications
Signaling Pathways
Cell Biology
Cancer Research
Areas of Focus
- Molecular regulatory mechanisms of genomic instability induced by chemical carcinogens and its role in cell malignant transformation and tumorigenesis
- Post-translational modifications of key transcription factors and their signaling pathway transduction abnormalities in relation to tumorigenesis and development
Work Experience
- 2011-present - Zhejiang University School of Medicine - Researcher in Pathology and Pathophysiology
Academic Background & Achievements
- 2004 - Master's Degree in Pharmacy: University of Calabria, Italy
- 2008 - PhD in Molecular Biology and Oncology: University of Calabria, Italy
- Received national scholarship for studying abroad
- Participated in multiple projects funded by Italian National Science Foundation and Health Foundation (MURST) and Italian Cancer Research Association (AIRC)
Publications
- Physical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy, Hongyan Qi, 2018
- ATR-CHK1-E2F3 signaling transactivates human ribonucleotide reductase small subunit M2 for DNA repair induced by the chemical carcinogen MNNG, Hongyan Qi, 2017
- Biphasic reduction of histone H3 phosphorylation in response to N-nitroso compounds induced DNA damage, Hongyan Qi, 2016
- Phosphorylation of the alpha-subunit of the eukaryotic initiation factor-2 (eIF2 alpha) alleviates benzo[a]pyrene-7,8-diol-9,10-epoxide induced cell cycle arrest and apoptosis in human cells, Hongyan Qi, 2015
- Interferon Regulatory Factor 1 Transactivates Expression of Human DNA Polymerase eta in Response to Carcinogen N-Methyl-N ''-nitro-N-nitrosoguanidine, Hongyan Qi, 2014
- Identification and functional implication of nuclear localization signals in the N-terminal domain of JMJD5, Hongyan Qi, 2013
- JMJD5 interacts with p53 and negatively regulates p53 function in control of cell cycle and proliferation, Hongyan Qi, 2012
- Non-enzymatic action of RRM1 protein upregulates PTEN leading to inhibition of colorectal cancer metastasis, Hongyan Qi, 2011
Awards
- National Scholarship for studying abroad
