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Qinghua Dong
dongqinghua@zju.edu.cn
Chinese, English
Zhejiang
Zhejiang University
Medical
  • 2001/03 - 2004/06 Ph.D. in Oncology: Zhejiang University
  • 1993/09 - 1996/06 Master's in Cell Biology: Wuhan University
  • 1989/09 - 1993/06 Bachelor's in Biology: Central China Normal University
  • 2010/11 - Present - Zhejiang University, Sir Run Run Shaw Hospital, Associate Researcher
  • 2007/09 - 2010/03 - University of California, Los Angeles, Postdoctoral Researcher
  • 2006/01 - 2010/10 - Zhejiang University, Associate Researcher
  • 1999/04 - 2005/12 - Zhejiang University, Assistant Researcher
  • 1996/07 - 1999/03 - Tongji Medical University, Teaching Assistant
Function of tumor-related genes
Small molecule anti-tumor drugs
  • Targeting Bmi-1 -mediated epithelial-mesenchymal transition to inhibit colorectal cancer liver metastasis., Xu ZY, Zhou Z, Zhang J, Xuan FC, Liuyang ZY, Fan MJ, Zhou DF, Ma XM, Hong YY, Wang YH, Sharma S, Dong QH, Wang GY, 2021
  • Sodium butyrate modulates gut microbiota and immune response in colorectal cancer liver metastatic mice., Ma X, Zhou Z, Zhang X, Fan M, Hong Y, Feng Y, Dong Q, Diao H, Wang G, 2020
  • MicroRNA-30b-5p functions as a metastasis suppressor in colorectal cancer by targeting Rap1b., Fan M, Ma X, Wang F, Zhou Z, Zhang J, Zhou D, Hong Y, Wang Y, Wang G, Dong Q, 2020
  • MiR-200c modulates the pathogenesis of radiation-induced oral mucositis., Tao J, Fan M, Zhou D, Hong Y, Zhang J, Liu H, Sharma S, Wang G, Dong Q, 2019
  • Sodium Butyrate Inhibits Colorectal Cancer Cell Migration by downregulating Bmi-1 through enhanced miR-200c expression., Xu Z, Tao J, Chen P, Chen L, Sharma S, Wang G, Dong Q, 2018
  • MicroRNA profile in HBV-induced infection and hepatocellular carcinoma., Wang G, Dong F, Xu Z, Sharma S, Chen D, Hu X, Zhang L, Zhang J, Dong Q, 2017
  • Nimotuzumab abrogates acquired radioresistance of KYSE-150R esophageal cancer cells by inhibiting EGFR signaling and cellular DNA repair., Liu H, Yang W, Gao H, Jiang T, Gu B, Dong Q, Xu W, Wu S, Sun X, 2015
  • Quercetin attenuates doxorubicin cardiotoxicity by modulating Bmi-1 expression., Dong Q, Chen L, Lu Q, Sharma S, Li L, Morimoto S, Wang G, 2014
  • HDAC inhibitors reverse acquired radio resistance of KYSE-150R esophageal carcinoma cells by modulating Bmi-1 expression., Dong Q, Sharma S, Liu H, Chen L, Gu B, Sun X, Wang G, 2014
  • Efavirenz induces autophagy and aberrant differentiation in normal human keratinocytes., Dong Q, Oh JE, Yi JK, Kim RH, Shin KH, Mitsuyasu R, Park NH, Kang MK, 2013
  • Quercetin potentiates doxorubicin mediated antitumor effects against liver cancer through p53/Bcl-xl., Wang GY, Zhang JW, Liu LY, Sharma S, Dong QH, 2012
  • Bmi-1 confers adaptive radioresistance to KYSE-150R esophageal carcinoma cells., Wang G, Liu L, Sharma S, Liu H, Yang W, Sun X, Dong Q, 2012
  • Autocrine endothelin-3/endothelin receptor B signaling maintains cellular and molecular properties of glioblastoma stem cells., Liu Y, Ye F, Yamada K, Tso JL, Zhang Y, Nguyen DH, Dong Q, Soto H, Choe J, Dembo A, Wheeler H, Eskin A, Schmid I, Yong WH, Mischel PS, Cloughesy TF, Kornblum HI, Nelson SF, Liau LM, Tso CL, 2011
  • Bisphosphonates induce senescence in normal human oral keratinocytes., Kim RH, Lee RS, Williams D, Bae S, Woo J, Lieberman M, Oh JE, Dong Q, Shin KH, Kang MK, Park NH, 2011
  • Radioprotective effects of Bmi-1 involve epigenetic silencing of its target genes and enhanced DNA repair in normal human keratinocytes., Dong Q, Oh JE, Chen W, Kim R, Kim RH, Shin KH, McBride WH, Park NH, Kang MK, 2011
  • Grainyhead-like 2 enhances the human telomerase reverse transcriptase gene expression by inhibiting DNA methylation at the 5'-CpG island in normal human keratinocytes., Chen W, Dong Q, Shin KH, Kim RH, Oh JE, Park NH, Kang MK, 2010
  • Molecular properties of CD133+ glioblastoma stem cells derived from treatment-refractory recurrent brain tumors., Liu Q, Nguyen DH, Dong Q, Shitaku P, Chung K, Liu OY, Tso JL, Liu JY, Konkankit V, Cloughesy TF, Mischel PS, Lane TF, Liau LM, Nelson SF, Tso CL, 2009
  • Berbamine induces Fas-mediated apoptosis in human hepatocellular carcinoma HepG2 cells and inhibits its tumor growth in nude mice., Wang GY, Lv QH, Dong Q, Xu RZ, Dong QH, 2009
  • Berbamine induces apoptosis in human hepatoma cell line SMMC7721 by loss in mitochondrial transmembrane potential and caspase activation., Wang GY, Zhang JW, Lv QH, Xu RZ, Dong QH, 2007
  • Berbamine: A novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity., Xu R, Dong Q, Yu Y, Zhao X, Gan X, Wu D, Lu Q, Xu X, Yu XF, 2006
  • Evaluation of ST13 gene expression in colorectal cancer patients., Dong QH, Zheng S, Hu Y, Chen GX, Ding JY, 2005
  • Overexpression of Shp2 tyrosine phosphatase is implicated in leukemogenesis in adult human leukemia., Xu R, Yu Y, Zheng S, Zhao X, Dong Q, Liang Y, Lu Q, Fang Y, Gan X, Xu X, Zhang S, Dong Q, Zhang X, Feng GS, 2005
Tumor Genes Oncology Cancer Genetics Biomarkers Therapy Molecular Biology Drug Development Pharmacology

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