Professor | Meng Qu | Asia Growth Partners

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Name	Meng Qu
Contact Information	mengqu@zju.edu.cn
Language ability	English, Chinese
Province	Zhejiang

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Name

Meng Qu

Contact Information

mengqu@zju.edu.cn

Language ability

English, Chinese

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	PhD: Beijing Institute of Life Sciences Postdoctoral Research: University of Southern California Postdoctoral Research: The Scripps Research Institute

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

PhD: Beijing Institute of Life Sciences
Postdoctoral Research: University of Southern California
Postdoctoral Research: The Scripps Research Institute

Areas of Focus	Research on the relationship and mechanisms between mammalian biological rhythms and human diseases
Publications	Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle, Meng Qu†, Guoxin Zhang†, Han Qu, Alexander Vu, Raymond Wu, Hidekazu Tsukamoto, Zhenyu Jia, Wendong Huang, Heinz-Josef Lenz, Jeremy N. Rich, and Steve A. Kay, 2023 HNF4A Defines Tissue-specific Circadian Rhythms by Beaconing BMAL1::CLOCK Chromatin Binding and Shaping the Rhythmic Chromatin Landscape, Meng Qu†, Han Qu†, Zhenyu Jia, and Steve A. Kay, 2021 Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock, Zhen Dong†, Guoxin Zhang†, Meng Qu†, Ryan C. Gimple, Qiulian Wu, Zhixin Qiu, Briana C. Prager, Xiuxing Wang, Leo J. Y. Kim, Andrew R. Morton, Deobrat Dixit, Wenchao Zhou, Haidong Huang, Bin Li, Zhe Zhu, Shideng Bao, Stephen C. Mack, Lukas Chavez, Steve A. Kay, and Jeremy N. Rich, 2019 Nuclear Receptor HNF4A Transrepresses CLOCK:BMAL1 and Modulates Tissue-Specific Circadian Networks, Meng Qu, Tomas Duffy, Tsuyoshi Hirota, and Steve A. Kay, 2018 Phosphorylation-Dependent Assembly and Coordination of the DNA Damage Checkpoint Apparatus by Rad4(TopBP1), Meng Qu†, Mathieu Rappas†, Christopher P. Wardlaw†, Valerie Garcia, Jing-Yi Ren, Matthew Day, Antony M. Carr, Antony W. Oliver, Li-Lin Du, and Laurence H. Pearl, 2013 Phosphorylation-Dependent Interactions between Crb2 and Chk1 Are Essential for DNA Damage Checkpoint, Meng Qu, Bing Yang, Li Tao, John R. Yates III, Paul Russell, Meng-Qiu Dong, and Li-Lin Du, 2012 The Actin Cytoskeleton-MRTF/SRF Cascade Transduces Cellular Physical Niche Cues to Entrain the Circadian Clock, Xuekai Xiong, Weini Li, Jin Nam, Meng Qu, Steve A. Kay, and Ke Ma, 2022 Clocking Cancer: The Circadian Clock as a Target in Cancer Therapy, Francesca Battaglin, Priscilla Chan, Yuanzhong Pan, Shivani Soni, Meng Qu, Erin R. Spiller, Sofi Castanon, Evanthia T. Roussos Torres, Shannon M. Mumenthaler, Steve A. Kay, and Heinz-Josef Lenz*, 2021

Areas of Focus

Research on the relationship and mechanisms between mammalian biological rhythms and human diseases

Publications

Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle, Meng Qu†, Guoxin Zhang†, Han Qu, Alexander Vu, Raymond Wu, Hidekazu Tsukamoto, Zhenyu Jia, Wendong Huang, Heinz-Josef Lenz, Jeremy N. Rich, and Steve A. Kay*, 2023
HNF4A Defines Tissue-specific Circadian Rhythms by Beaconing BMAL1::CLOCK Chromatin Binding and Shaping the Rhythmic Chromatin Landscape, Meng Qu†*, Han Qu†, Zhenyu Jia, and Steve A. Kay*, 2021
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock, Zhen Dong†, Guoxin Zhang†, Meng Qu†, Ryan C. Gimple, Qiulian Wu, Zhixin Qiu, Briana C. Prager, Xiuxing Wang, Leo J. Y. Kim, Andrew R. Morton, Deobrat Dixit, Wenchao Zhou, Haidong Huang, Bin Li, Zhe Zhu, Shideng Bao, Stephen C. Mack, Lukas Chavez, Steve A. Kay*, and Jeremy N. Rich*, 2019
Nuclear Receptor HNF4A Transrepresses CLOCK:BMAL1 and Modulates Tissue-Specific Circadian Networks, Meng Qu, Tomas Duffy, Tsuyoshi Hirota, and Steve A. Kay*, 2018
Phosphorylation-Dependent Assembly and Coordination of the DNA Damage Checkpoint Apparatus by Rad4(TopBP1), Meng Qu†, Mathieu Rappas†, Christopher P. Wardlaw†, Valerie Garcia, Jing-Yi Ren, Matthew Day, Antony M. Carr*, Antony W. Oliver*, Li-Lin Du*, and Laurence H. Pearl*, 2013
Phosphorylation-Dependent Interactions between Crb2 and Chk1 Are Essential for DNA Damage Checkpoint, Meng Qu, Bing Yang, Li Tao, John R. Yates III, Paul Russell, Meng-Qiu Dong, and Li-Lin Du*, 2012
The Actin Cytoskeleton-MRTF/SRF Cascade Transduces Cellular Physical Niche Cues to Entrain the Circadian Clock, Xuekai Xiong, Weini Li, Jin Nam, Meng Qu, Steve A. Kay, and Ke Ma*, 2022
Clocking Cancer: The Circadian Clock as a Target in Cancer Therapy, Francesca Battaglin, Priscilla Chan, Yuanzhong Pan, Shivani Soni, Meng Qu, Erin R. Spiller, Sofi Castanon, Evanthia T. Roussos Torres, Shannon M. Mumenthaler, Steve A. Kay, and Heinz-Josef Lenz*, 2021

Biological Rhythms Human Diseases Mammalian Mechanisms Genetics Biochemistry Cell Biology Epigenetics Tumor Clinical Translation

Di Wang - Zhejiang University

Yan Luo - Zhejiang University

Ping Liang - Zhejiang University

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