Professor | Zhengping Shao | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Zhengping Shao
Contact Information	zhengping_shao@zju.edu.cn
Language ability	Chinese, English
Province	Zhejiang

Upload Avatar (500 x 500)

Name

Zhengping Shao

Contact Information

zhengping_shao@zju.edu.cn

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	2012.09-2014.06 Ph.D. in Clinical Medicine (Oncology): Zhejiang University School of Medicine 2007.09-2012.06 Ph.D. in Pathology and Pathophysiology: Zhejiang University School of Medicine 2003.09-2007.06 Bachelor's in Information Engineering (Optoelectronics): Zhejiang University School of Information Science and Engineering
Work Experience	2022.05-present - Zhejiang University School of Medicine - Researcher 2019.09-2022.04 - Columbia University Medical Center - Associate Researcher 2014.12-2019.08 - Columbia University Medical Center - Postdoctoral Researcher 2009.09-2011.09 - University of Texas Southwestern Medical Center - Visiting Scholar (Joint Ph.D. Student)

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

2012.09-2014.06 Ph.D. in Clinical Medicine (Oncology): Zhejiang University School of Medicine
2007.09-2012.06 Ph.D. in Pathology and Pathophysiology: Zhejiang University School of Medicine
2003.09-2007.06 Bachelor's in Information Engineering (Optoelectronics): Zhejiang University School of Information Science and Engineering

Work Experience

2022.05-present - Zhejiang University School of Medicine - Researcher
2019.09-2022.04 - Columbia University Medical Center - Associate Researcher
2014.12-2019.08 - Columbia University Medical Center - Postdoctoral Researcher
2009.09-2011.09 - University of Texas Southwestern Medical Center - Visiting Scholar (Joint Ph.D. Student)

Areas of Focus	Genomic Instability DNA Damage and Repair Tumorigenesis and Development
Publications	DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis, Shao, Z, Flynn, RA, Crowe, JL, Zhu, Y, Liang, J, Jiang, W, Aryan, F, Aoude, P, Bertozzi, CR, Estes, VM et al., 2020 Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo, Shao, Z, Lee, BJ, Rouleau-Turcotte, E, Langelier, MF, Lin, X, Estes, VM, Pascal, JM, and Zha, S., 2020 Kinase-dependent structural role of DNA-PKcs during immunoglobulin class switch recombination, Crowe JL, Shao Z, Wang XS, Wei PC, Jiang W, Lee BJ, Estes VM, Alt FW, Zha S., 2018 DNA damage-induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice, Wang XS, Menolfi D, Wu-Baer F, Fangazio M, Meyer SN, Shao Z, Wang Y, Zhu Y, Lee BJ, Estes VM, Cupo OM, Gautier J, Pasqualucci L, Dalla-Favera R, Baer R, Zha S., 2021 XRCC1 prevents toxic PARP1 trapping during DNA base excision repair, Demin AA, Hirota K, Tsuda M, Adamowicz M, Hailstone R, Brazina J, Gittens W, Kalasova I, Shao Z, Zha S, Sasanuma H, Hanzlikova H, Takeda S, Caldecott KW., 2021 FATC Domain Deletion Compromises ATM Protein Stability, Blocks Lymphocyte Development, and Promotes Lymphomagenesis, Milanovic M, Shao Z, Estes VM, Wang XS, Menolfi D, Lin X, Lee BJ, Xu J, Cupo OM, Wang D, Zha S., 2021 DNA-PKcs phosphorylation at the T2609 cluster alters the repair pathway choice during immunoglobulin class switch recombination, Crowe, JL, Wang, XS, Shao, Z, Lee, BJ, Estes, VM and Zha, S., 2020 CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining, Wang XS, Zhao J, Wu-Baer F, Shao Z, Lee BJ, Cupo OM, Rabadan R, Gautier J, Baer R, Zha S., 2020 Phosphorylation at S2053 in Murine (S2056 in Human) DNA-PKcs Is Dispensable for Lymphocyte Development and Class Switch Recombination, Jiang W, Estes VM, Wang XS, Shao Z, Lee BJ, Lin X, Crowe JL, Zha S., 2019 CtIP is essential for early B cell proliferation and development in mice, Liu X, Wang XS, Lee BJ, Wu-Baer FK, Lin X, Shao Z, Estes VM, Gautier J, Baer R, Zha S., 2019 Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA, Menolfi D, Jiang W, Lee BJ, Moiseeva T, Shao Z, Estes V, Frattini MG, Bakkenist CJ, Zha S., 2018

Areas of Focus

Genomic Instability
DNA Damage and Repair
Tumorigenesis and Development

Publications

DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis, Shao, Z, Flynn, RA, Crowe, JL, Zhu, Y, Liang, J, Jiang, W, Aryan, F, Aoude, P, Bertozzi, CR, Estes, VM et al., 2020
Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo, Shao, Z, Lee, BJ, Rouleau-Turcotte, E, Langelier, MF, Lin, X, Estes, VM, Pascal, JM, and Zha, S., 2020
Kinase-dependent structural role of DNA-PKcs during immunoglobulin class switch recombination, Crowe JL, Shao Z, Wang XS, Wei PC, Jiang W, Lee BJ, Estes VM, Alt FW, Zha S., 2018
DNA damage-induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice, Wang XS, Menolfi D, Wu-Baer F, Fangazio M, Meyer SN, Shao Z, Wang Y, Zhu Y, Lee BJ, Estes VM, Cupo OM, Gautier J, Pasqualucci L, Dalla-Favera R, Baer R, Zha S., 2021
XRCC1 prevents toxic PARP1 trapping during DNA base excision repair, Demin AA, Hirota K, Tsuda M, Adamowicz M, Hailstone R, Brazina J, Gittens W, Kalasova I, Shao Z, Zha S, Sasanuma H, Hanzlikova H, Takeda S, Caldecott KW., 2021
FATC Domain Deletion Compromises ATM Protein Stability, Blocks Lymphocyte Development, and Promotes Lymphomagenesis, Milanovic M, Shao Z, Estes VM, Wang XS, Menolfi D, Lin X, Lee BJ, Xu J, Cupo OM, Wang D, Zha S., 2021
DNA-PKcs phosphorylation at the T2609 cluster alters the repair pathway choice during immunoglobulin class switch recombination, Crowe, JL, Wang, XS, Shao, Z, Lee, BJ, Estes, VM and Zha, S., 2020
CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining, Wang XS, Zhao J, Wu-Baer F, Shao Z, Lee BJ, Cupo OM, Rabadan R, Gautier J, Baer R, Zha S., 2020
Phosphorylation at S2053 in Murine (S2056 in Human) DNA-PKcs Is Dispensable for Lymphocyte Development and Class Switch Recombination, Jiang W, Estes VM, Wang XS, Shao Z, Lee BJ, Lin X, Crowe JL, Zha S., 2019
CtIP is essential for early B cell proliferation and development in mice, Liu X, Wang XS, Lee BJ, Wu-Baer FK, Lin X, Shao Z, Estes VM, Gautier J, Baer R, Zha S., 2019
Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA, Menolfi D, Jiang W, Lee BJ, Moiseeva T, Shao Z, Estes V, Frattini MG, Bakkenist CJ, Zha S., 2018

Genomic Instability Dna Damage Dna Repair Tumorigenesis Lymphoma Breast Cancer Live Cell Imaging Mouse Models Bioinformatics Dna-Pkcs

Jichun Zhou - Zhejiang University

Ting Liu - Zhejiang University

Hongyan Qi - Zhejiang University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us