Professor | 邵正萍 | 数字化转型顾问

	Upload Avatar (500 x 500)
Name	邵正萍
Contact Information	zhengping_shao@zju.edu.cn
Language ability	中文, 英语
Province	浙江

Upload Avatar (500 x 500)

Name

邵正萍

Contact Information

zhengping_shao@zju.edu.cn

Language ability

中文, 英语

Province

浙江

University/Lab Affiliation and Title	浙江大学
Faculty	Medical
Academic Background & Achievements	2012.09-2014.06 临床医学（肿瘤学）博士: 浙江大学医学院 2007.09-2012.06 病理学与病理生理学博士: 浙江大学医学院 2003.09-2007.06 信息工程（光电系）学士: 浙江大学信息科学与工程学院
Work Experience	2022.05至今 - 浙江大学医学院 - 研究员 2019.09-2022.04 - 美国哥伦比亚大学医学院 - 副研究员 2014.12-2019.08 - 美国哥伦比亚大学医学院 - 博士后 2009.09-2011.09 - 美国德州大学西南医学中心 - 访问学者（联合培养博士生）

University/Lab Affiliation and Title

浙江大学

Faculty

Medical

Academic Background & Achievements

2012.09-2014.06 临床医学（肿瘤学）博士: 浙江大学医学院
2007.09-2012.06 病理学与病理生理学博士: 浙江大学医学院
2003.09-2007.06 信息工程（光电系）学士: 浙江大学信息科学与工程学院

Work Experience

2022.05至今 - 浙江大学医学院 - 研究员
2019.09-2022.04 - 美国哥伦比亚大学医学院 - 副研究员
2014.12-2019.08 - 美国哥伦比亚大学医学院 - 博士后
2009.09-2011.09 - 美国德州大学西南医学中心 - 访问学者（联合培养博士生）

Areas of Focus	基因组不稳定性 DNA损伤与修复肿瘤发生与发展
Publications	DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis, Shao, Z, Flynn, RA, Crowe, JL, Zhu, Y, Liang, J, Jiang, W, Aryan, F, Aoude, P, Bertozzi, CR, Estes, VM et al., 2020 Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo, Shao, Z, Lee, BJ, Rouleau-Turcotte, E, Langelier, MF, Lin, X, Estes, VM, Pascal, JM, and Zha, S., 2020 Kinase-dependent structural role of DNA-PKcs during immunoglobulin class switch recombination, Crowe JL, Shao Z, Wang XS, Wei PC, Jiang W, Lee BJ, Estes VM, Alt FW, Zha S., 2018 DNA damage-induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice, Wang XS, Menolfi D, Wu-Baer F, Fangazio M, Meyer SN, Shao Z, Wang Y, Zhu Y, Lee BJ, Estes VM, Cupo OM, Gautier J, Pasqualucci L, Dalla-Favera R, Baer R, Zha S., 2021 XRCC1 prevents toxic PARP1 trapping during DNA base excision repair, Demin AA, Hirota K, Tsuda M, Adamowicz M, Hailstone R, Brazina J, Gittens W, Kalasova I, Shao Z, Zha S, Sasanuma H, Hanzlikova H, Takeda S, Caldecott KW., 2021 FATC Domain Deletion Compromises ATM Protein Stability, Blocks Lymphocyte Development, and Promotes Lymphomagenesis, Milanovic M, Shao Z, Estes VM, Wang XS, Menolfi D, Lin X, Lee BJ, Xu J, Cupo OM, Wang D, Zha S., 2021 DNA-PKcs phosphorylation at the T2609 cluster alters the repair pathway choice during immunoglobulin class switch recombination, Crowe, JL, Wang, XS, Shao, Z, Lee, BJ, Estes, VM and Zha, S., 2020 CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining, Wang XS, Zhao J, Wu-Baer F, Shao Z, Lee BJ, Cupo OM, Rabadan R, Gautier J, Baer R, Zha S., 2020 Phosphorylation at S2053 in Murine (S2056 in Human) DNA-PKcs Is Dispensable for Lymphocyte Development and Class Switch Recombination, Jiang W, Estes VM, Wang XS, Shao Z, Lee BJ, Lin X, Crowe JL, Zha S., 2019 CtIP is essential for early B cell proliferation and development in mice, Liu X, Wang XS, Lee BJ, Wu-Baer FK, Lin X, Shao Z, Estes VM, Gautier J, Baer R, Zha S., 2019 Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA, Menolfi D, Jiang W, Lee BJ, Moiseeva T, Shao Z, Estes V, Frattini MG, Bakkenist CJ, Zha S., 2018

Areas of Focus

基因组不稳定性
DNA损伤与修复
肿瘤发生与发展

Publications

DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis, Shao, Z, Flynn, RA, Crowe, JL, Zhu, Y, Liang, J, Jiang, W, Aryan, F, Aoude, P, Bertozzi, CR, Estes, VM et al., 2020
Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo, Shao, Z, Lee, BJ, Rouleau-Turcotte, E, Langelier, MF, Lin, X, Estes, VM, Pascal, JM, and Zha, S., 2020
Kinase-dependent structural role of DNA-PKcs during immunoglobulin class switch recombination, Crowe JL, Shao Z, Wang XS, Wei PC, Jiang W, Lee BJ, Estes VM, Alt FW, Zha S., 2018
DNA damage-induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice, Wang XS, Menolfi D, Wu-Baer F, Fangazio M, Meyer SN, Shao Z, Wang Y, Zhu Y, Lee BJ, Estes VM, Cupo OM, Gautier J, Pasqualucci L, Dalla-Favera R, Baer R, Zha S., 2021
XRCC1 prevents toxic PARP1 trapping during DNA base excision repair, Demin AA, Hirota K, Tsuda M, Adamowicz M, Hailstone R, Brazina J, Gittens W, Kalasova I, Shao Z, Zha S, Sasanuma H, Hanzlikova H, Takeda S, Caldecott KW., 2021
FATC Domain Deletion Compromises ATM Protein Stability, Blocks Lymphocyte Development, and Promotes Lymphomagenesis, Milanovic M, Shao Z, Estes VM, Wang XS, Menolfi D, Lin X, Lee BJ, Xu J, Cupo OM, Wang D, Zha S., 2021
DNA-PKcs phosphorylation at the T2609 cluster alters the repair pathway choice during immunoglobulin class switch recombination, Crowe, JL, Wang, XS, Shao, Z, Lee, BJ, Estes, VM and Zha, S., 2020
CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining, Wang XS, Zhao J, Wu-Baer F, Shao Z, Lee BJ, Cupo OM, Rabadan R, Gautier J, Baer R, Zha S., 2020
Phosphorylation at S2053 in Murine (S2056 in Human) DNA-PKcs Is Dispensable for Lymphocyte Development and Class Switch Recombination, Jiang W, Estes VM, Wang XS, Shao Z, Lee BJ, Lin X, Crowe JL, Zha S., 2019
CtIP is essential for early B cell proliferation and development in mice, Liu X, Wang XS, Lee BJ, Wu-Baer FK, Lin X, Shao Z, Estes VM, Gautier J, Baer R, Zha S., 2019
Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA, Menolfi D, Jiang W, Lee BJ, Moiseeva T, Shao Z, Estes V, Frattini MG, Bakkenist CJ, Zha S., 2018

基因组不稳定性 Dna损伤 Dna修复肿瘤发生淋巴瘤乳腺癌活细胞成像小鼠模型生物信息学 Dna-Pkcs

刘婷 - 浙江大学

周济春 - 浙江大学

View All

Personal Information

Academic Information

Research

联系我们

还未创建账户?

Personal Information

Academic Information

Research

联系我们