Professor | 孟飞龙 | 数字化转型顾问

Name	孟飞龙
Contact Information	Feilong.Meng@SIBCB.ac.cn
Language ability	中文, 英语
Province	上海

Name

孟飞龙

Contact Information

Feilong.Meng@SIBCB.ac.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	中国科学院大学
Faculty	Medical School
Academic Background & Achievements	2003-09--2007-07 博士研究生: 中国科学院上海生命科学研究院生物化学与细胞生物学研究所 1999-09--2003-06 本科学士: 南开大学
Work Experience	2015/10-今 - 中国科学院上海生命科学研究院生物化学与细胞生物学研究所 - 研究员, 博士生导师, 研究组长 2009/11-2015/09 - 美国哈佛大学医学院/波士顿儿童医院/霍华德休斯医学研究所 - 博士后
Awards	2016: 国家自然科学基金优秀青年科学基金 2016: 中组部第12批青年**** 2015: 哈佛大学医学院华人学者生命科学研究年度奖 2014-15: 美国淋巴癌研究基金会博士后基金 2011-13: 美国癌症研究所博士后基金 2009: 中国科学院院长奖 2002: 中国科学院奖学金 2001: 南开大学生命科学学院-德普公司奖学金

University/Lab Affiliation and Title

中国科学院大学

Faculty

Medical School

Academic Background & Achievements

2003-09--2007-07 博士研究生: 中国科学院上海生命科学研究院生物化学与细胞生物学研究所
1999-09--2003-06 本科学士: 南开大学

Work Experience

2015/10-今 - 中国科学院上海生命科学研究院生物化学与细胞生物学研究所 - 研究员, 博士生导师, 研究组长
2009/11-2015/09 - 美国哈佛大学医学院/波士顿儿童医院/霍华德休斯医学研究所 - 博士后

Awards

2016: 国家自然科学基金优秀青年科学基金
2016: 中组部第12批青年****
2015: 哈佛大学医学院华人学者生命科学研究年度奖
2014-15: 美国淋巴癌研究基金会博士后基金
2011-13: 美国癌症研究所博士后基金
2009: 中国科学院院长奖
2002: 中国科学院奖学金
2001: 南开大学生命科学学院-德普公司奖学金

Areas of Focus	免疫系统多样化和肿瘤抑制的机制超级增强子、对向转录和长非编码RNA在DNA脱氨基和免疫系统多样化中的作用
Publications	The Mechanism of Class Switch Recombination, Meng FL, Alt FW, Tian M, 2014 Mechanisms of programmed DNA lesions and genomic instability in the immune system, Alt FW, Zhang Y, Meng FL, Guo C, Schwer B, 2013 Convergent Transcription At Intragenic Super-Enhancers Targets AID-initiated Genomic Instability, Meng FL, Du Z, Federation A, Hu J, Wang Q, Kieffer-Kwon KR, Meyers RM, Amor C, Wasserman CR, Neuberg D, Casellas R, Nussenzweig M, Bradner JE#, Liu XS#, Alt FW#, 2014 The RNA Exosome Targets Activation Induced Cytidine Deaminase to Both Strands of Transcribed Duplex DNA Substrates, Basu U, Meng FL, Keim C, Grinstein V, Pefanis E, Eccleston J, Zhang T, Myers D, Wasserman CR, Wesemann DR, Januszyk K, Gregory RI, Deng H, Lima CD, Alt FW, 2011 A Rapid Embryonic Stem Cell–Based Mouse Model for B-cell Lymphomas Driven by Epstein–Barr Virus Protein LMP1, Ba Z, Meng FL, Gostissa M, Huang PY, Ke Q, Wang Z, Dao MN, Fujiwara Y, Rajewsky K, Zhang B, and Alt FW, 2015 Sua5p is required for telomere recombination in Saccharomyces cerevisiae, Meng FL, Chen XF, Hu Y, Tang HB, Dang W and Zhou JQ, 2010 Sua5p a Single-stranded Telomeric DNA Binding Protein Facilitates Telomere Replication, Meng FL, Hu Y, Shen N, Tong XJ, Wang J, Ding J and Zhou JQ, 2009 Candida albicans, a distinctive fungal model for cellular aging study, Fu XH, Meng FL, Hu Y, Zhou JQ, 2008 AID Recognizes Structured DNA for Class Switch Recombination, Qiao Q, Wang L, Meng FL, Hwang JK, Alt FW and Wu H, 2017 Phosphatidylinositol 3-kinase delta blockade increases genomic instability in B cells, Compagno M, Wang Q, Pighi C, Cheong TC, Meng FL, Poggio T, Yeap LS, Karaca E, Blasco RB, Langellotto F, Ambrogio C, Voena C, Wiestner A, Kasar SN, Brown JR, Sun J, Wu CJ, Gostissa M, Alt FW and Chiarle R, 2017 Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching, Dong J, Panchakshari RA, Zhang T, Zhang Y, Hu J, Volpi SA, Meyers RM, Ho YJ, Du Z, Robbiani DF, Meng F, Gostissa M, Nussenzweig MC, Manis JP, Alt FW, 2015 Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes, Hu J, Zhang Y, Zhao L, Frock RL, Du Z, Meyers RM, Meng FL, Schatz DG, Alt FW, 2015 Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody Genes, Yeap LS, Hwang JK*, Du Z, Meyers RM, Meng FL, Jakubauskaite A, Liu M, Mani V, Neuberg D, Kepler TB, Wang JH and Alt FW, 2015

Areas of Focus

免疫系统多样化和肿瘤抑制的机制
超级增强子、对向转录和长非编码RNA在DNA脱氨基和免疫系统多样化中的作用

Publications

The Mechanism of Class Switch Recombination, Meng FL, Alt FW, Tian M, 2014
Mechanisms of programmed DNA lesions and genomic instability in the immune system, Alt FW, Zhang Y, Meng FL, Guo C, Schwer B, 2013
Convergent Transcription At Intragenic Super-Enhancers Targets AID-initiated Genomic Instability, Meng FL*, Du Z*, Federation A*, Hu J, Wang Q, Kieffer-Kwon KR, Meyers RM, Amor C, Wasserman CR, Neuberg D, Casellas R, Nussenzweig M, Bradner JE#, Liu XS#, Alt FW#, 2014
The RNA Exosome Targets Activation Induced Cytidine Deaminase to Both Strands of Transcribed Duplex DNA Substrates, Basu U*, Meng FL*, Keim C*, Grinstein V, Pefanis E, Eccleston J, Zhang T, Myers D, Wasserman CR, Wesemann DR, Januszyk K, Gregory RI, Deng H, Lima CD, Alt FW, 2011
A Rapid Embryonic Stem Cell–Based Mouse Model for B-cell Lymphomas Driven by Epstein–Barr Virus Protein LMP1, Ba Z*, Meng FL*, Gostissa M*, Huang PY, Ke Q, Wang Z, Dao MN, Fujiwara Y, Rajewsky K, Zhang B, and Alt FW, 2015
Sua5p is required for telomere recombination in Saccharomyces cerevisiae, Meng FL, Chen XF, Hu Y, Tang HB, Dang W and Zhou JQ, 2010
Sua5p a Single-stranded Telomeric DNA Binding Protein Facilitates Telomere Replication, Meng FL, Hu Y, Shen N, Tong XJ, Wang J, Ding J and Zhou JQ, 2009
Candida albicans, a distinctive fungal model for cellular aging study, Fu XH*, Meng FL*, Hu Y, Zhou JQ, 2008
AID Recognizes Structured DNA for Class Switch Recombination, Qiao Q, Wang L, Meng FL, Hwang JK, Alt FW and Wu H, 2017
Phosphatidylinositol 3-kinase delta blockade increases genomic instability in B cells, Compagno M, Wang Q, Pighi C, Cheong TC, Meng FL, Poggio T, Yeap LS, Karaca E, Blasco RB, Langellotto F, Ambrogio C, Voena C, Wiestner A, Kasar SN, Brown JR, Sun J, Wu CJ, Gostissa M, Alt FW and Chiarle R, 2017
Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching, Dong J, Panchakshari RA, Zhang T, Zhang Y, Hu J, Volpi SA, Meyers RM, Ho YJ, Du Z, Robbiani DF, Meng F, Gostissa M, Nussenzweig MC, Manis JP, Alt FW, 2015
Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes, Hu J, Zhang Y, Zhao L, Frock RL, Du Z, Meyers RM, Meng FL, Schatz DG, Alt FW, 2015
Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody Genes, Yeap LS*, Hwang JK*, Du Z, Meyers RM, Meng FL, Jakubauskaite A, Liu M, Mani V, Neuberg D, Kepler TB, Wang JH and Alt FW, 2015

免疫系统多样化肿瘤抑制超级增强子对向转录长非编码Rna Dna脱氨基 B细胞基因组不稳定性 Dna损伤

孟凡岩 - 南京大学

Area of Focus
免疫系统 | 抗体 | 疫苗 | 自体免疫 | 炎症 | T细胞 | B细胞 | 病原体 | 免疫疗法 | 细胞因子

姚根宏 - 南京大学

Area of Focus
免疫系统 | 抗体 | 疫苗 | 自身免疫 | 炎症 | T细胞 | B细胞 | 病原体 | 细胞因子 | 免疫治疗

View All

Personal Information

Academic Information

Research

联系我们

还未创建账户?

Personal Information

Academic Information

Research

联系我们