Professor | Jian Ruan | Asia Growth Partners

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Name	Jian Ruan
Contact Information	software233@zju.edu.cn
Language ability	Chinese, English
Province	Zhejiang

Upload Avatar (500 x 500)

Name

Jian Ruan

Contact Information

software233@zju.edu.cn

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Areas of Focus	Research on the pathogenesis of liver tumors
Publications	EMLI-ICC: an ensemble machine learning-based integration algorithm for metastasis prediction and risk stratification in intrahepatic cholangiocarcinoma, Jian Ruan, Shuaishuai Xu, Ruyin Chen, Wenxin Qu, Qiong Li, Chanqi Ye, Wei Wu, Qi Jiang, Feifei Yan, Enhui Shen, Qinjie Chu, Yunlu Jia, Xiaochen Zhang, Wenguang Fu, Jinzhang Chen, Michael P Timko, Peng Zhao, Longjiang Fan, Yifei Shen, 2022 Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing-Assisted Multi-Omics Analysis, Bao X, Li Q, Chen J, Chen D, Ye C, Dai X, Wang Y, Li X, Rong X, Cheng F, Jiang M, Zhu Z, Ding Y, Sun R, Liu C, Huang L, Jin Y, Li B, Lu J, Wu W, Guo Y, Fu W, Langley SR, Tano V, Fang W, Guo T, Sheng J, Zhao P, Ruan J, 2022 Proteomic and single-cell landscape reveals novel pathogenic mechanisms of HBV infected intrahepatic cholangiocarcinom, Shen YF, Xu SS, Ye CQ, Li Q, Chen RY, Wu W, Jiang Q, Jia YL, Zhang XC, Fan LJ, Fu WG, Jiang M, Chen JZ, Timko MP, Zhao P, Ruan J, 2023 Immunotherapy of cholangiocarcinoma: Therapeutic strategies and predictive biomarkers, Ruyin Chen, Dandan Zheng, Qiong Li, Shuaishuai Xu, Chanqi Ye, Qi Jiang, Feifei Yan, Yunlu Jia, Xiaochen Zhang, Jian Ruan, 2022 The emerging role of ubiquitin-specific protease 20 in tumorigenesis and cancer therapeutics, Li Q, Ye C, Tian T, Jiang Q, Zhao P, Wang X, Liu F, Shan J, Ruan J, 2022 Modulation of the tumour microenvironment in hepatocellular carcinoma by tyrosine kinase inhibitors: from modulation to combination therapy targeting the microenvironment, Chen R, Li Q, Xu S, Ye C, Tian T, Jiang Q, Shan J, Ruan J, 2022 The Landscape and Clinical Application of the Tumor Microenvironment in Gastroenteropancreatic Neuroendocrine Neoplasms, Shuaishuai Xu, Chanqi Ye, Ruyin Chen, Qiong Li, Ruan J, 2022 Cancer cell membrane-wrapped nanoparticles for cancer immunotherapy: A review of current developments, Qi Jiang, Mixue Xie, Ruyin Chen, Feifei Yan, Chanqi ye, Qiong Li, Shuaishuai Xu, Wei Wu, Yunlu Jia, Peng Shen, Jian Ruan, 2022 Depiction of the genomic and genetic landscape identifies CCL5 as a protective factor in colorectal neuroendocrine carcinoma, Dong Chen, Xuanwen Bao, Ruyi Zhang, Yongfeng Ding, Min Zhang, Benfeng Li, Hangyu Zhang, Xiaolin Li, Zhou Tong, Lulu Liu, Xiaohu Zhou, Saisai Wang, Xiaofei Cheng, Yi Zheng, Jian Ruan, Weijia Fang, Peng Zhao, 2021 FOXC2 is a prognostic biomarker and contributes to the growth and invasion of human hepatocellular carcinoma, Jinzhang Chen, Xiaoxiang Rong, Xinhui Liu, Dayong Zheng, Xiaodong Rong, Fengsheng Chen, Peng Zhao, Feiye Liu, Jian Ruan, 2020 Enhanced radiotherapy efficacy and induced anti-tumor immunity in HCC by improving hypoxia microenvironment using oxygen microcapsules, Xiaomeng Dai, Jian Ruan, Yixuan Guo, Zhu Sun, Junqing Liu, Xuanwen Bao, Hangyu Zhang, Qiong Li, Chanqi Ye, Xun Wang, Chun-Xia Zhao, Feng Zhou, Jianpeng Sheng, Dong Chen, Peng Zhao, 2021 Lossless enrichment of trace analytes in levitating droplets for multiphase and multiplex detection, Chen X, Ding Q, Bi C, Ruan J, Yang S, 2022 Assessment of Global Trends in the Diagnosis of Mesothelioma From 1990 to 2017, Zhai Z, Ruan J, Zheng Y, Xiang D, Li N, Hu J, Shen J, Deng Y, Yao J, Zhao P, Wang S, Yang S, Zhou L, Wu Y, Xu P, Lyu L, Lyu J, Bergan R, Chen T, Dai Z, 2021 Biocompatible snowman-like tumor-targeting dimer nanoparticles for improved delivery efficiency and enhanced anti-tumor therapy, Chanqi Ye, Xiaoxiao Yan, Xiaomeng Dai, Ruyin Chen, Qiong Li, Shuaishuai Xu, Qi Jiang, Feifei Yan, Suzhen Xu, Chun-Xia Zhao, Peng Zhao, Dong Chen, Jian Ruan, 2023 Induction of Tumor Ferroptosis-Dependent Immunity via an Injectable Attractive Pickering Emulsion Gel, Dai X, Zhang J, Bao X, Guo Y, Jin Y, Yang C, Zhang H, Liu L, Gao Y, Ye C, Wu W, Liu C, Zhao CX, Sheng J, Ren E, Li H, Fang W, Wu B, Ruan J, Gu Z, Chen D, Zhao P, 2023 A multiomics analysis-assisted deep learning model identifies a macrophage-oriented module as a potential therapeutic target in colorectal cancer, Xuanwen Bao, Qiong Li, Dong Chen, Xiaomeng Dai, Chuan Liu, Weihong Tian, Hangyu Zhang, Yuzhi Jin, Yin Wang, Jinlin Cheng, Chunyu Lai, Chanqi Ye, Shan Xin, Xin Li, Ge Su, Yongfeng Ding, Yangyang Xiong, Jindong Xie, Vincent Tano, Yanfang Wang, Wenguang Fu, Shuiguang Deng, Weijia Fang, Jianpeng Sheng, Jian Ruan, Peng Zhao, 2024

Areas of Focus

Research on the pathogenesis of liver tumors

Publications

EMLI-ICC: an ensemble machine learning-based integration algorithm for metastasis prediction and risk stratification in intrahepatic cholangiocarcinoma, Jian Ruan, Shuaishuai Xu, Ruyin Chen, Wenxin Qu, Qiong Li, Chanqi Ye, Wei Wu, Qi Jiang, Feifei Yan, Enhui Shen, Qinjie Chu, Yunlu Jia, Xiaochen Zhang, Wenguang Fu, Jinzhang Chen, Michael P Timko, Peng Zhao, Longjiang Fan, Yifei Shen, 2022
Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing-Assisted Multi-Omics Analysis, Bao X, Li Q, Chen J, Chen D, Ye C, Dai X, Wang Y, Li X, Rong X, Cheng F, Jiang M, Zhu Z, Ding Y, Sun R, Liu C, Huang L, Jin Y, Li B, Lu J, Wu W, Guo Y, Fu W, Langley SR, Tano V, Fang W, Guo T, Sheng J, Zhao P, Ruan J, 2022
Proteomic and single-cell landscape reveals novel pathogenic mechanisms of HBV infected intrahepatic cholangiocarcinom, Shen YF, Xu SS, Ye CQ, Li Q, Chen RY, Wu W, Jiang Q, Jia YL, Zhang XC, Fan LJ, Fu WG, Jiang M, Chen JZ, Timko MP, Zhao P, Ruan J, 2023
Immunotherapy of cholangiocarcinoma: Therapeutic strategies and predictive biomarkers, Ruyin Chen, Dandan Zheng, Qiong Li, Shuaishuai Xu, Chanqi Ye, Qi Jiang, Feifei Yan, Yunlu Jia, Xiaochen Zhang, Jian Ruan, 2022
The emerging role of ubiquitin-specific protease 20 in tumorigenesis and cancer therapeutics, Li Q, Ye C, Tian T, Jiang Q, Zhao P, Wang X, Liu F, Shan J, Ruan J, 2022
Modulation of the tumour microenvironment in hepatocellular carcinoma by tyrosine kinase inhibitors: from modulation to combination therapy targeting the microenvironment, Chen R, Li Q, Xu S, Ye C, Tian T, Jiang Q, Shan J, Ruan J, 2022
The Landscape and Clinical Application of the Tumor Microenvironment in Gastroenteropancreatic Neuroendocrine Neoplasms, Shuaishuai Xu, Chanqi Ye, Ruyin Chen, Qiong Li, Ruan J, 2022
Cancer cell membrane-wrapped nanoparticles for cancer immunotherapy: A review of current developments, Qi Jiang, Mixue Xie, Ruyin Chen, Feifei Yan, Chanqi ye, Qiong Li, Shuaishuai Xu, Wei Wu, Yunlu Jia, Peng Shen, Jian Ruan, 2022
Depiction of the genomic and genetic landscape identifies CCL5 as a protective factor in colorectal neuroendocrine carcinoma, Dong Chen, Xuanwen Bao, Ruyi Zhang, Yongfeng Ding, Min Zhang, Benfeng Li, Hangyu Zhang, Xiaolin Li, Zhou Tong, Lulu Liu, Xiaohu Zhou, Saisai Wang, Xiaofei Cheng, Yi Zheng, Jian Ruan, Weijia Fang, Peng Zhao, 2021
FOXC2 is a prognostic biomarker and contributes to the growth and invasion of human hepatocellular carcinoma, Jinzhang Chen, Xiaoxiang Rong, Xinhui Liu, Dayong Zheng, Xiaodong Rong, Fengsheng Chen, Peng Zhao, Feiye Liu, Jian Ruan, 2020
Enhanced radiotherapy efficacy and induced anti-tumor immunity in HCC by improving hypoxia microenvironment using oxygen microcapsules, Xiaomeng Dai, Jian Ruan, Yixuan Guo, Zhu Sun, Junqing Liu, Xuanwen Bao, Hangyu Zhang, Qiong Li, Chanqi Ye, Xun Wang, Chun-Xia Zhao, Feng Zhou, Jianpeng Sheng, Dong Chen, Peng Zhao, 2021
Lossless enrichment of trace analytes in levitating droplets for multiphase and multiplex detection, Chen X, Ding Q, Bi C, Ruan J, Yang S, 2022
Assessment of Global Trends in the Diagnosis of Mesothelioma From 1990 to 2017, Zhai Z, Ruan J, Zheng Y, Xiang D, Li N, Hu J, Shen J, Deng Y, Yao J, Zhao P, Wang S, Yang S, Zhou L, Wu Y, Xu P, Lyu L, Lyu J, Bergan R, Chen T, Dai Z, 2021
Biocompatible snowman-like tumor-targeting dimer nanoparticles for improved delivery efficiency and enhanced anti-tumor therapy, Chanqi Ye, Xiaoxiao Yan, Xiaomeng Dai, Ruyin Chen, Qiong Li, Shuaishuai Xu, Qi Jiang, Feifei Yan, Suzhen Xu, Chun-Xia Zhao, Peng Zhao, Dong Chen, Jian Ruan, 2023
Induction of Tumor Ferroptosis-Dependent Immunity via an Injectable Attractive Pickering Emulsion Gel, Dai X, Zhang J, Bao X, Guo Y, Jin Y, Yang C, Zhang H, Liu L, Gao Y, Ye C, Wu W, Liu C, Zhao CX, Sheng J, Ren E, Li H, Fang W, Wu B, Ruan J, Gu Z, Chen D, Zhao P, 2023
A multiomics analysis-assisted deep learning model identifies a macrophage-oriented module as a potential therapeutic target in colorectal cancer, Xuanwen Bao, Qiong Li, Dong Chen, Xiaomeng Dai, Chuan Liu, Weihong Tian, Hangyu Zhang, Yuzhi Jin, Yin Wang, Jinlin Cheng, Chunyu Lai, Chanqi Ye, Shan Xin, Xin Li, Ge Su, Yongfeng Ding, Yangyang Xiong, Jindong Xie, Vincent Tano, Yanfang Wang, Wenguang Fu, Shuiguang Deng, Weijia Fang, Jianpeng Sheng, Jian Ruan, Peng Zhao, 2024

Liver Tumors Pathogenesis Clinical Research Basic Research Hepatocellular Carcinoma Tumor Microenvironment Immunotherapy Molecular Targeting Single-Cell Analysis Machine Learning

Huang He - Zhejiang University

Dan Zhang - Zhejiang University

Xin-Yang Hu - Zhejiang University

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