Professor | 阮健 | 数字化转型顾问

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Name	阮健
Contact Information	software233@zju.edu.cn
Language ability	中文, 英语
Province	浙江

Upload Avatar (500 x 500)

Name

阮健

Contact Information

software233@zju.edu.cn

Language ability

中文, 英语

Province

浙江

University/Lab Affiliation and Title	浙江大学
Faculty	Medical

University/Lab Affiliation and Title

浙江大学

Faculty

Medical

Areas of Focus	肝脏肿瘤的发病机制研究
Publications	EMLI-ICC: an ensemble machine learning-based integration algorithm for metastasis prediction and risk stratification in intrahepatic cholangiocarcinoma, 阮健, 徐帅帅, 陈如音, 曲文欣, 李琼, 叶禅祺, 吴伟, 江琦, 严飞飞, 沈恩辉, 褚勤杰, 贾云露, 张晓晨, 傅文光, 陈金章, Michael P Timko, 赵鹏, 范龙江, 沈一飞, 2022 Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing-Assisted Multi-Omics Analysis, 包翔, 李琼, 陈健, 陈东, 叶禅祺, 戴晓, 王宇, 李晓, 荣翔, 程飞, 江明, 朱志, 丁一, 孙睿, 刘晨, 黄亮, 金玉, 李斌, 陆军, 吴伟, 郭勇, 傅文光, Langley SR, Tano V, 方伟, 郭涛, 盛建, 赵鹏, 阮健, 2022 Proteomic and single-cell landscape reveals novel pathogenic mechanisms of HBV infected intrahepatic cholangiocarcinom, 沈一飞, 徐帅帅, 叶禅祺, 李琼, 陈如音, 吴伟, 江琦, 贾云露, 张晓晨, 范龙江, 傅文光, 江明, 陈金章, Timko MP, 赵鹏, 阮健, 2023 Immunotherapy of cholangiocarcinoma: Therapeutic strategies and predictive biomarkers, 陈如音, 郑丹丹, 李琼, 徐帅帅, 叶禅祺, 江琦, 严飞飞, 贾云露, 张晓晨, 阮健, 2022 The emerging role of ubiquitin-specific protease 20 in tumorigenesis and cancer therapeutics, 李琼, 叶禅祺, 田甜, 江琦, 赵鹏, 王晓, 刘飞, 单俊, 阮健, 2022 Modulation of the tumour microenvironment in hepatocellular carcinoma by tyrosine kinase inhibitors: from modulation to combination therapy targeting the microenvironment, 陈如音, 李琼, 徐帅帅, 叶禅祺, 田甜, 江琦, 单俊, 阮健, 2022 The Landscape and Clinical Application of the Tumor Microenvironment in Gastroenteropancreatic Neuroendocrine Neoplasms, 徐帅帅, 叶禅祺, 陈如音, 李琼, 阮健, 2022 Cancer cell membrane-wrapped nanoparticles for cancer immunotherapy: A review of current developments, 江琦, 谢米雪, 陈如音, 严飞飞, 叶禅祺, 李琼, 徐帅帅, 吴伟, 贾云露, 沈鹏, 阮健, 2022 Depiction of the genomic and genetic landscape identifies CCL5 as a protective factor in colorectal neuroendocrine carcinoma, 陈东, 包轩文, 张如意, 丁永峰, 张敏, 李本峰, 张航宇, 李晓林, 童周, 刘璐璐, 周小虎, 王赛赛, 程晓飞, 郑毅, 阮健, 方伟佳, 赵鹏, 2021 FOXC2 is a prognostic biomarker and contributes to the growth and invasion of human hepatocellular carcinoma, 陈金章, 荣晓翔, 刘新辉, 郑大勇, 荣晓东, 陈凤生, 赵鹏, 刘飞叶, 阮健, 2020 Enhanced radiotherapy efficacy and induced anti-tumor immunity in HCC by improving hypoxia microenvironment using oxygen microcapsules, 戴晓, 阮健, 郭亦轩, 孙竹, 刘俊庆, 包轩文, 张航宇, 李琼, 叶禅祺, 王迅, 赵春霞, 周峰, 盛建鹏, 陈东, 赵鹏, 2021 Lossless enrichment of trace analytes in levitating droplets for multiphase and multiplex detection, 陈晓, 丁强, 毕成, 阮健, 杨松, 2022 Assessment of Global Trends in the Diagnosis of Mesothelioma From 1990 to 2017, 翟志, 阮健, 郑毅, 项东, 李宁, 胡杰, 沈建, 邓勇, 姚军, 赵鹏, 王松, 杨松, 周磊, 吴勇, 徐鹏, 吕林, 吕军, Bergan R, 陈涛, 戴志, 2021 Biocompatible snowman-like tumor-targeting dimer nanoparticles for improved delivery efficiency and enhanced anti-tumor therapy, 叶禅祺, 严晓晓, 戴晓, 陈如音, 李琼, 徐帅帅, 江琦, 严飞飞, 徐苏珍, 赵春霞, 赵鹏, 陈东, 阮健, 2023 Induction of Tumor Ferroptosis-Dependent Immunity via an Injectable Attractive Pickering Emulsion Gel, 戴晓, 张健, 包轩文, 郭亦轩, 金玉, 杨晨, 张航, 刘璐, 高阳, 叶禅祺, 吴伟, 刘晨, 赵春霞, 盛建, 任尔, 李辉, 方伟, 吴波, 阮健, 顾志, 陈东, 赵鹏, 2023 A multiomics analysis-assisted deep learning model identifies a macrophage-oriented module as a potential therapeutic target in colorectal cancer, 包轩文, 李琼, 陈东, 戴

Areas of Focus

肝脏肿瘤的发病机制研究

Publications

EMLI-ICC: an ensemble machine learning-based integration algorithm for metastasis prediction and risk stratification in intrahepatic cholangiocarcinoma, 阮健, 徐帅帅, 陈如音, 曲文欣, 李琼, 叶禅祺, 吴伟, 江琦, 严飞飞, 沈恩辉, 褚勤杰, 贾云露, 张晓晨, 傅文光, 陈金章, Michael P Timko, 赵鹏, 范龙江, 沈一飞, 2022
Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing-Assisted Multi-Omics Analysis, 包翔, 李琼, 陈健, 陈东, 叶禅祺, 戴晓, 王宇, 李晓, 荣翔, 程飞, 江明, 朱志, 丁一, 孙睿, 刘晨, 黄亮, 金玉, 李斌, 陆军, 吴伟, 郭勇, 傅文光, Langley SR, Tano V, 方伟, 郭涛, 盛建, 赵鹏, 阮健, 2022
Proteomic and single-cell landscape reveals novel pathogenic mechanisms of HBV infected intrahepatic cholangiocarcinom, 沈一飞, 徐帅帅, 叶禅祺, 李琼, 陈如音, 吴伟, 江琦, 贾云露, 张晓晨, 范龙江, 傅文光, 江明, 陈金章, Timko MP, 赵鹏, 阮健, 2023
Immunotherapy of cholangiocarcinoma: Therapeutic strategies and predictive biomarkers, 陈如音, 郑丹丹, 李琼, 徐帅帅, 叶禅祺, 江琦, 严飞飞, 贾云露, 张晓晨, 阮健, 2022
The emerging role of ubiquitin-specific protease 20 in tumorigenesis and cancer therapeutics, 李琼, 叶禅祺, 田甜, 江琦, 赵鹏, 王晓, 刘飞, 单俊, 阮健, 2022
Modulation of the tumour microenvironment in hepatocellular carcinoma by tyrosine kinase inhibitors: from modulation to combination therapy targeting the microenvironment, 陈如音, 李琼, 徐帅帅, 叶禅祺, 田甜, 江琦, 单俊, 阮健, 2022
The Landscape and Clinical Application of the Tumor Microenvironment in Gastroenteropancreatic Neuroendocrine Neoplasms, 徐帅帅, 叶禅祺, 陈如音, 李琼, 阮健, 2022
Cancer cell membrane-wrapped nanoparticles for cancer immunotherapy: A review of current developments, 江琦, 谢米雪, 陈如音, 严飞飞, 叶禅祺, 李琼, 徐帅帅, 吴伟, 贾云露, 沈鹏, 阮健, 2022
Depiction of the genomic and genetic landscape identifies CCL5 as a protective factor in colorectal neuroendocrine carcinoma, 陈东, 包轩文, 张如意, 丁永峰, 张敏, 李本峰, 张航宇, 李晓林, 童周, 刘璐璐, 周小虎, 王赛赛, 程晓飞, 郑毅, 阮健, 方伟佳, 赵鹏, 2021
FOXC2 is a prognostic biomarker and contributes to the growth and invasion of human hepatocellular carcinoma, 陈金章, 荣晓翔, 刘新辉, 郑大勇, 荣晓东, 陈凤生, 赵鹏, 刘飞叶, 阮健, 2020
Enhanced radiotherapy efficacy and induced anti-tumor immunity in HCC by improving hypoxia microenvironment using oxygen microcapsules, 戴晓, 阮健, 郭亦轩, 孙竹, 刘俊庆, 包轩文, 张航宇, 李琼, 叶禅祺, 王迅, 赵春霞, 周峰, 盛建鹏, 陈东, 赵鹏, 2021
Lossless enrichment of trace analytes in levitating droplets for multiphase and multiplex detection, 陈晓, 丁强, 毕成, 阮健, 杨松, 2022
Assessment of Global Trends in the Diagnosis of Mesothelioma From 1990 to 2017, 翟志, 阮健, 郑毅, 项东, 李宁, 胡杰, 沈建, 邓勇, 姚军, 赵鹏, 王松, 杨松, 周磊, 吴勇, 徐鹏, 吕林, 吕军, Bergan R, 陈涛, 戴志, 2021
Biocompatible snowman-like tumor-targeting dimer nanoparticles for improved delivery efficiency and enhanced anti-tumor therapy, 叶禅祺, 严晓晓, 戴晓, 陈如音, 李琼, 徐帅帅, 江琦, 严飞飞, 徐苏珍, 赵春霞, 赵鹏, 陈东, 阮健, 2023
Induction of Tumor Ferroptosis-Dependent Immunity via an Injectable Attractive Pickering Emulsion Gel, 戴晓, 张健, 包轩文, 郭亦轩, 金玉, 杨晨, 张航, 刘璐, 高阳, 叶禅祺, 吴伟, 刘晨, 赵春霞, 盛建, 任尔, 李辉, 方伟, 吴波, 阮健, 顾志, 陈东, 赵鹏, 2023
A multiomics analysis-assisted deep learning model identifies a macrophage-oriented module as a potential therapeutic target in colorectal cancer, 包轩文, 李琼, 陈东, 戴

肝脏肿瘤发病机制临床研究基础研究肝细胞癌肿瘤微环境免疫治疗分子靶向单细胞分析机器学习

黄河 - 浙江大学

李晓明 - 浙江大学

张丹 - 浙江大学

Area of Focus
生殖健康 | 发育源性 | 疾病机制 | 临床研究 | 基础研究 | 配子 | 胚胎 | 预防 | 遗传学 | 妇产科

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