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Chuansheng Guo
Medical School
Zhejiang University
Zhejiang
Language: English, Chinese
Immunometabolism
Inflammatory Diseases
Metabolic Diseases
Tumor Immunity
Dendritic Cells
Glutamine Signalling
Nlrp3 Inflammasome
Cholesterol Homeostasis
Bile Acids
Pyroptosis
Areas of Focus
- Immunometabolism
- Tumor Immunity
Work Experience
- 2017-2018 - Zhejiang University School of Medicine - Postdoctoral Researcher
- 2018-2023 - St. Jude Children's Research Hospital - Postdoctoral Researcher
- 2023-Present - Zhejiang University - Researcher
Academic Background & Achievements
- 2017 - PhD in Immunology: Zhejiang University
- Published multiple academic papers in top journals such as Nature and Immunity
Publications
- SLC38A2 and glutamine signalling in cDC1s dictate anti-tumour immunity, Chuansheng Guo, Zhiyuan You, Hao Shi, Yu Sun, Xingrong Du, Gustavo Palacios, Cliff Guy, Sujing Yuan, Nicole M. Chapman, Seon Ah Lim, Xiang Sun, Jordy Saravia, Sherri Rankin, Yogesh Dhungana, and Hongbo Chi, 2023
- Cholesterol Homeostatic Regulator SCAP-SREBP2 integrates NLRP3 inflammasome activation and cholesterol biosynthetic signaling in macrophages, Chuansheng Guo, Zhexu Chi, Danlu Jiang, Ting Xu, Weiwei Yu, Zhen Wang, Sheng Chen, Li Zhang, Qianyun Liu, Xingchen Guo, Xue Zhang, Wenxin Li, Linrong Lu, Yingliang Wu, Bao-Liang Song and Di Wang, 2018
- Bile acids control inflammation and metabolic disorder through inhibition of NLRP3 inflammasome, Chuansheng Guo, Shujun Xie, Zhexu Chi, Jinhua Zhang, Yangyang Liu, Li Zhang, Mingzhu Zheng, Xue Zhang, Yuehai Ke, Linrong Lu, and Di Wang, 2016
- Immunometabolism of dendritic cells in health and disease, Chuansheng Guo, & Hongbo Chi, 2023
- Tespa1 negatively regulates FceRI-mediated signaling and the mast cell-mediated allergic response, Di Wang, Mingzhu Zheng, Yuanjun Qiu, Chuansheng Guo, Jian Ji, Lei Lei, Xue Zhang, Xuetao Cao, Yi Ting Zhou and Linrong Lu, 2014
- Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1,4,5-trisphosphate receptors, Jingjing Liang, Jun Lyu, Meng Zhao, Dan Li, Mingzhu Zheng, Yan Fang, Fangzhu Zhao, Jun Lou, Chuansheng Guo, Lie Wang, Di Wang, Wanli Liu, and Linrong Lu, 2017
- A rapid administration of GW4064 inhibits the NLRP3 inflammasome activation independent of farnesoid X receptor agonism, Xie S, Guo C, Chi Z, Huang B, Wu Y, Wang D, Xia D, 2017
- Type I IFN operates pyroptosis and necroptosis during multidrug-resistant A. baumannii infection, Yang Li, Xiaomin Guo, Chunmiao Hu, Yan Du, Chuansheng Guo, Di Wang, Weiheng Zhao, Gonghua Huang, Chunliang Li, Qiumin Lu, Ren Lai, Tao Xu, Xiaopeng Qi, 2018
