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Liang Zhao
Medical School
Zhejiang University
Zhejiang
Language: English, Chinese, German
Kidney Injury
Diabetic Nephropathy
Hypertensive Nephropathy
Microvascular Function
Septic Acute Kidney Injury
Mechanisms
Research
Disease
Microcirculation
Vascular Tension
Areas of Focus
- Mechanisms of acute and chronic kidney injury, diabetic nephropathy, and hypertensive nephropathy
- Role and mechanisms of microvascular function in kidney diseases
- Mechanisms of septic acute kidney injury
Academic Background & Achievements
- PhD: Zhejiang University, School of Medicine
- Postdoctoral Research: Humboldt University of Berlin, Charité Medical School
- Published over 20 papers in SCI journals including Hypertension, Free Radic Biol Med, Acta Physiologica
Publications
- Kidney renin release under hypoxia and its potential link with nitric oxide: a narrative review, Kong W, Liao Y, Zhao L, Hall N, Zhou H, Liu R, Persson PB, Lai E, 2023
- Dihydromyricetin attenuates cisplatin-induced acute kidney injury by reducing oxidative stress, inflammation and ferroptosis, Xu Z, Zhang M, Wang W, Zhou S, Yu M, Qiu X, Jiang S, Wang X, Tang C, Li S, Wang C, Zhu R, Peng W, Zhao L, Fu X, Patzak A, Persson PB, Zhao L, Mao J, Shu Q, Lai EY, Zhang G, 2023
- Tacrolimus Causes Hypertension by Increasing Vascular Contractility via RhoA (Ras Homolog Family Member A)/ROCK (Rho-Associated Protein Kinase) Pathway in Mice, Wang X, Jiang S, Fei L, Dong F, Xie L, Qiu X, Lei Y, Guo J, Zhong M, Ren X, Yang Y, Zhao L, Zhang G, Wang H, Tang C, Yu L, Liu R, Patzak A, Persson PB, Hultström, M, Wei Q, Lai EY, Zheng Z, 2022
- Analysis of pyroptosis-related immune signatures and identification of pyroptosis-related lncRNAs prognostic signature in clear cell renal cell carcinoma, Zhong M, Wang X, Zhu E, Gong L, Fei L, Zhao L, Wu K, Tang C, Zhang L, Wang Z, Zheng Z, 2022
- rhADAMTS13 inhibits oxidative stress by cleaving vWF in ischemia/reperfusion-induced acute kidney injury, Zhou S, Guo J, Liao X, Zhou Q, Qiu X, Jiang S, Xu N, Wang X, Zhao L, Hu W, Xie L, Xie P, Cui Y, Yang Y, Patzak A, Persson PB, Mao J, Lai EY, 2022
- Captopril related kidney damage: renal afferent arteriolar responses to angiotensin II and inflammatory signaling, Zhou S, Huang Q, Zhou Y, Cai X, Cui Y, Zhou Q, Guo J, Jiang S, Xu N, Cheng J, Li L, Lai EY, Zhao L, 2022
- Trimethylamine N-oxide promotes hyperoxaluria-induced calcium oxalate deposition and kidney injury by activating autophagy, Dong F, Jiang S, Tang C, Wang X, Ren X, Wei Q, Tian J, Hu W, Guo J, Fu X, Liu L, Patzak A, Persson PB, Guo F, Lai EY, Zhao L, 2022
- Knockout of macula densa neuronal nitric oxide synthase increases blood pressure in db/db mice, Zhang J, Wang X, Cui Y, Jiang S, Wei J, Jiang S, Chan J, Thalakola A, Le T, Xu L, Zhao L, Wang L, Jiang K, Cheng F, Patel T, Buggs J, Vallon V, Liu R, 2021
- Gut microbiota dependent trimethylamine N-oxide aggravates angiotensin II-induced hypertension, Jiang S, Shui Y, Cui Y, Tang C, Wang X, Qiu X, Hu W, Fei L, Li Y, Zhang S, Zhao L, Xu N, Dong F, Ren X, Liu R, Persson PB, Patzak A, Lai EY, Wei Q, Zheng Z, 2021
- High phosphate impairs arterial endothelial function through AMPK-related pathways in mouse resistance arteries, Hu W, Jiang S, Liao Y, Li J, Dong F, Guo J, Wang X, Fei L, Cui Y, Ren X, Xu N, Zhao L, Chen L, Zheng Y, Li L, Patzak A, Persson PB, Zheng Z, Lai EY, 2021
- ADAMTS13 inhibits oxidative stress and ameliorates progressive chronic kidney disease following ischemia/reperfusion injury, Zhou S, Guo J, Zhao L, Liao Y, Zhou Q, Cui Y, Hu W, Chen J, Ren X, Wei Q, Jiang S, Zheng Y, Li L, Wilcox CS, Persson PB, Patzak A, Tian J, Lai EY, 2021
- Role of soluble guanylyl cyclase in renal afferent and efferent arterioles, Wennysia IC, Zhao L, Schomber T, Braun D, Golz S, Summer H, Benardeau A, Lai EY, Lichtenberger FB, Schubert R, Persson PB, Xu M, Patzak A, 2021
- Acute kidney injury sensitizes the brain vasculature to angiotensin II constriction via FGFBP1, Zhao L, Cao X, Li L, Wang Q, Zhou S, Xu N, Jiang S, Chen L, Schmidt MQ, Wei Q, Zhao J, Labes R, Patzak A, Wilcox CS, Fu X, Wellstein A, Lai EY, 2020
- NaHCO3 dilates mouse afferent arteriole via Na+/HCO3- cotransporters NBCs, Jiang S, Wang X, Wei J, Zhang G, Zhang J, Xie P, Xu L, Wang L, Zhao L, Li L, Wilcox CS, Chen J, Lai EY, Liu R, 2019
- ADAMTS13 protects mice against renal ischemia/reperfusion injury by reducing inflammation and improving endothelial function, Zhou S, Jiang S, Guo J, Xu N, Wang Q, Zhang G, Zhao L, Zhou Q, Fu X, Li L, Patzak A, Hultström M, Lai EY, 2019
- Fenofibrate improves vascular endothelial function and contractility in diabetic mice, Xu N, Wang Q, Jiang S, Wang Q, Hu W, Zhou S, Zhao L, Xie L, Chen J, Wellstein A, Lai EY, 2019
- Enhanced Renal Afferent Arteriolar Reactive Oxygen Species and Contractility to Endothelin-1 Are Associated with Canonical Wnt Signaling in Diabetic Mice, Zhang S, Huang Q, Wang Q, Wang Q, Cao X, Zhao L, Xu N, Zhuge Z, Mao J, Fu X, Liu R, Wilcox CS, Patzak A, Li L, Lai EY, 2018
- High-salt diet induces outward remodeling of efferent arterioles in mice with reduced renal mass, Zhao L, Gao Y, Cao X, Gao D, Zhou S, Zhang S, Cai X, Han F, Wilcox CS, Li L, Lai EY, 2017
- Increased hydrogen peroxide impairs angiotensin II contractions of afferent arterioles in mice after renal ischaemia-reperfusion injury, Huang Q, Wang Q, Zhang S, Jiang S, Zhao L, Yu L, Hultström M, Patzak A, Li L, Wilcox CS, Lai EY, 2016
- Endothelium -dependent and -independent Vasorelaxant Actions and Mechanisms Induced by Total Flavonoids of Elsholtzia Splendens in Rat Aortas, Wang H, Lu J, Zhang G, Li X, Peng H, Lu Y, Zhao L, Ye Z, Bruce IC, Xia Q, Qian L, 2014
- Effect of total flavones of Elsholtzia splendens in isolated ischemia/reperfusion rat hearts, Zhao L, Li Z, Qian L, Ye Z, Zhang G, Peng H, Xia Q, Wang H, 2014
