Areas of Focus
- Epigenetics and cell fate regulation
- Chromatin regulation in terminal erythroid differentiation
- Molecular mechanisms of CART cell immunotherapy
Publications
- CpG island reconfiguration for the establishment and synchronization of polycomb functions upon exit from naive pluripotency, Dawei Huo, Zhaowei Yu, Rui Li, Meihan Gong, Simone Sidoli, Xukun Lu, Yuying Hou, Zhongye Dai, Yu Kong, Guifen Liu, Ole N. Jensen, Wei Xie, Kristian Helin, Chaoyang Xiong, Guohong Li, Yong Zhang, and Xudong Wu, 2022
- JMJD6 modulates DNA damage response through downregulating H4K16ac independently of its enzymatic activity, Dawei Huo, Hao Chen, Yiming Cheng, Xin Song, Kai Zhang, Mulin Jun Li, Chenghao Xuan, 2020
- ncHMR detector: a computational framework to systematically reveal nonclassical functions of histone modification regulators, Shengen Hu, Dawei Huo, Zhaowei Yu, Yujie Chen, Jin Liu, Lin Liu, Xudong Wu, Yong Zhang, 2020
- An epigenetic circuit controls neurogenic programs during neocortex development, Wang A, Wang J, Tian K, Huo D, Ye H, Li S, Zhao C, Zhang B, Zheng Y, Xu L, Hua X, Wang K, Wu QF, Wu X, Zeng T, Liu Y, Zhou Y, 2021
- mTORC2 regulates hierarchical micro/nano topography-induced osteogenic differentiation via promoting cell adhesion and cytoskeletal polymerization, Gao Q, Hou Y, Li Z, Hu J, Huo D, Zheng H, Zhang J, Yao X, Gao R, Wu X, Sui L, 2021
- Nuclear DEK preserves hematopoietic stem cells potential via NCoR1/HDAC3-Akt1/2-mTOR axis, Chen Z, Huo D, Li L, Liu Z, Li Z, Xu S, Huang Y, Wu W, Zhou C, Liu Y, Kuang M, Wu F, Li H, Qian P, Song G, Wu X, Chen J, Hou Y, 2021
- Abnormal neocortex arealization and Sotos-like syndrome-associated behavior in Setd2 mutant mice, Xu L, Zheng Y, Li X, Wang A, Huo D, Li Q, Wang S, Luo Z, Liu Y, Xu F, Wu X, Wu M, Zhou Y, 2021
- Generation and validation of versatile inducible CRISPRi embryonic stem cell and mouse model, Li R, Xia X, Wang X, Sun X, Dai Z, Huo D, Zheng H, Xiong H, He A, Wu X, 2020
- PRMT2 links histone H3R8 asymmetric dimethylation to oncogenic activation and tumorigenesis of glioblastoma, Dong F, Li Q, Yang C, Huo D, Wang X, Ai C, Kong Y, Sun X, Wang W, Zhou Y, Liu X, Li W, Gao W, Liu W, Kang C, Wu X, 2018
- Ubiquitin ligase RNF20/40 facilitates spindle assembly and promotes breast carcinogenesis through stabilizing motor protein Eg5, Duan Y, Huo D, Gao J, Wu H, Ye Z, Liu Z, Zhang K, Shan L, Zhou X, Wang Y, Su D, Ding X, Shi L, Wang Y, Shang Y, Xuan C, 2016