Areas of Focus
- Structural biology of cell surface receptors, especially G protein-coupled receptors (GPCRs)
Work Experience
- 2018-Present Researcher at School of Life Sciences, East China Normal University
- 2014-2017 Associate Research Professor at iHuman Institute, ShanghaiTech University
- 2009-2014 Postdoctoral Fellow at Department of Biochemistry and Molecular Pharmacology, Harvard Medical School
Academic Background & Achievements
- 2006-2009 PhD in Structural and Molecular Biology, Institute of Biophysics, Chinese Academy of Sciences
- 2003-2006 Master of Science in Biochemistry and Molecular Biology, Beijing Normal University
- 1999-2003 Bachelor of Science in Basic Medical Sciences, Anhui Medical University
Publications
- Unveiling Mechanical Activation: GAIN Domain Unfolding and Dissociation in Adhesion GPCRs, Fu C, Huang W, Tang Q, Niu M, Guo S, Langenhan T, Song G, Yan J, 2023
- Structural insights into MIC2 recognition by MIC2-associated protein in Toxoplasma gondii, Zhang S, Wang F, Zhang D, Liu D, Ding W, Springer TA, Song G, 2023
- Crystal Structure of the Extracellular Domains of GPR110, Wang F, Wang Y, Qiu W, Zhang Q, Yang H, Song G, 2023
- Cryo-EM structure of the human adenosine A2B receptor-Gs signaling complex, Chen Y, Zhang J, Weng Y, Xu Y, Lu W, Liu W, Liu M, Hua T, Song G, 2022
- Engineering a precise adenine base editor with minimal bystander editing, Chen L, Zhang S, Xue N, Hong M, Zhang X, Zhang D, Yang J, Bai S, Huang Y, Meng H, Wu H, Luan C, Zhu B, Ru G, Gao H, Zhong L, Liu M, Liu M, Cheng Y, Yi C, Wang L, Zhao Y, Song G, Li D, 2022
- Crystal structure of a constitutive active mutant of adenosine A2A receptor, Cui M, Zhou Q, Xu Y, Weng Y, Yao D, Zhao S, Song G, 2022
- Structural basis for CD97 recognition of the decay-accelerating factor CD55 suggests mechanosensitive activation of adhesion GPCRs, Niu M, Xu S, Yang J, Yao D, Li N, Yan J, Zhong G, Song G, 2021
- Full length human GLP1 receptor structure without orthosteric ligands, Wu F, Yang L, Hang K, Laursen M, Wu L, Han GW, Ren Q, Roed NK, Lin G, Hanson MA, Jiang HL, Wang MW, Reedtz-Runge S, Song G, Stevens RC, 2020
- Mutagenesis facilitated crystallization of GLP-1R, Xu Y, Wang Y, Wang Y, Liu K, Peng Y, Yao D, Tao H, Liu H, Song G, 2019
- Protein crystal quality oriented disulfide bond engineering, Pu M, Xu Z, Peng Y, Hou Y, Liu D, Wang Y, Liu H, Song G, Liu ZJ, 2017
- Biochemical features of the adhesion G protein-coupled receptor CD97 for its functions of auto-proteolysis and HeLa cell attachment, Yang L, Liu X, Yang Y, Tang Y, Zhang M, Tan M, Cheng S, Xu Y, Yang L, Yang H, Song G, Huang W, 2017
- Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators, Song G, Yang D, Wang Y, Graaf CD, Zhou Q, Jiang S, Liu K, Cai X, Dai A, Lin G, Liu D, Wu F, Wu Y, Zhao S, Ye L, Han GW, Lau J, Wu B, Hanson MA, Liu ZJ, Wang MW, Steven RC, 2017
- Structure of the full-length glucagon class B G protein-coupled receptor, Zhang H, Qiao A, Yang D, Yang L, Dai A, Graaf Cd, Reedtz-Runge S, Dharmarajan V, Zhang H, Han GW, Grant TD, Sierra R, Weierstall U, Nelson G, Liu W, Wu Y, Ma L, Cai X, Lin G, Geng Z, Dong Y, Song G, Griffin PR, Lau J, Cherezov V, Yang H, Hanson MA, Stevens RC, Jiang H, Wang MW, Zhao Q, Wu B, 2017
- Extending the Structural View of Class B GPCRs, de Graaf C, Song G, Cao C, Zhao Q, Wang MW, Wu B, Stevens RC, 2017
- Structures of the Toxoplasma gliding motility adhesin, Song G, Springer TA, 2014
- Crystal structure of N-terminal domain of human cytokine- induced apoptosis inhibitor anamorsin, Song G, Cheng C, Li Y, Shaw N, Xiao ZC, Liu ZJ, 2014
- Shape change in the receptor for gliding motility in plasmodium sporozoites, Song G, Koksal AC, Lu C, Springer TA, 2012
- Structural insight into acute intermittent porphyria, Song G, Li Y, Cheng C, Zhao Y, Gao A, Zhang R, Joachimiak A, Shaw N, Liu ZJ, 2009
