Professor | Jingtao Guo | Asia Growth Partners

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Name	Jingtao Guo
Contact Information	jingtao.guo@ioz.ac.cn
Language ability	English, Chinese
Province	Beijing

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Name

Jingtao Guo

Contact Information

jingtao.guo@ioz.ac.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Chinese Academy of Sciences
Faculty	Institute of Zoology
Academic Background & Achievements	2013 - Bachelor of Science: Peking University 2018 - PhD in Cancer Science: University of Utah Postdoctoral Research: University of Utah School of Medicine
Work Experience	2020-07 - University of Utah School of Medicine - Tenure-track Assistant Professor 2021-12 - Chinese Academy of Sciences Institute of Zoology - Research Group Leader

University/Lab Affiliation and Title

Chinese Academy of Sciences

Faculty

Institute of Zoology

Academic Background & Achievements

2013 - Bachelor of Science: Peking University
2018 - PhD in Cancer Science: University of Utah
Postdoctoral Research: University of Utah School of Medicine

Work Experience

2020-07 - University of Utah School of Medicine - Tenure-track Assistant Professor
2021-12 - Chinese Academy of Sciences Institute of Zoology - Research Group Leader

Areas of Focus	Molecular mechanisms of spermatogonial stem cell self-renewal and differentiation In vivo and in vitro models for human spermatogonial stem cells Molecular mechanisms of male infertility and new treatment methods
Publications	Single-cell multi-omics analysis of human testicular germ cell tumor reveals its molecular features and microenvironment., Lu X, Luo Y, Nie X, Zhang B, Wang X, Li R, Liu G, Zhou Q, Liu Z, Fan L, Hotaling JM, Zhang Z, Bo H, Guo J., 2023 Single-cell analysis of the developing human ovary defines distinct insights into ovarian somatic and germline progenitors., Wamaitha SE, Nie X, Pandolfi EC, Wang X, Yang Y, Stukenborg JB, Cairns BR, Guo J, Clark AT., 2023 Single-cell analysis of human testis aging and correlation with elevated body mass index., Nie X, Munyoki SK, Sukhwani M, Schmid N, Missel A, Emery BR, DonorConnect, Stukenborg JB, Mayerhofer A, Orwig KE, Aston KI, Hotaling JM, Cairns BR, Guo J., 2022 Comparative Single-Cell Analysis of Biopsies Clarifies Pathogenic Mechanisms in Klinefelter Syndrome., Mahyari E, Guo J, Lima AC, Vigh-Conrad KA, Nie X, Nagirnaja L, Rockweiler N, Carrell DT, Hotaling JM, Aston KI, Conrad DF., 2021 Single-Cell Analysis of the Developing Human Testis Reveals Somatic Niche Cell Specification and Fetal Germline Stem Cell Establishment., Guo J, Sosa E, Chitiashvili T, Nie X, Rojas EJ, Oliver E, DonorConnect, Hotaling JM, Stukenborg J, Clark AT, Cairns BR., 2021 NRF2 Loss Recapitulates Heritable Impacts of Paternal Cigarette Smoke Exposure., Murphy PJ, Guo J, Jenkins TG, James ER, Hoidal JR, Huecksteadt J, Hotaling JM, Carrell DT, Cairns BR, Aston KI., 2020 No Evidence of SARS-CoV-2 in Semen of Males Recovering from COVID-19., Pan F, Xiao X, Guo J, Song Y, Li H, Patel DP, Spivak AM, Alukal JP, Zhang X, Xiong C, Li PS, Hotaling JM., 2020 The Dynamic Transcriptional Cell Atlas of Testis Development During Human Puberty., Guo J, Nie X, Giebler M, Mlcochova H, Wang Y, Grow EJ, DonorConnect, Kim R, Tharmaligham M, Matilionyte G, Mitchell RT, Lindskog L, Carrell DT, Goriely A, Hotaling JM, Cairns BR., 2020 The Adult Human Testis Transcriptional Cell Atlas., Guo J, Grow EJ, Mlcochova H, Maher GJ, Lindskog C, Nie X, Guo Y, Takei Y, Yun J, Cai L, Kim R, Carrell DT, Goriely A, Hotaling JM, Cairns BR., 2018 Chromatin and Single-Cell RNA-seq Profiling Reveal Dynamic Signaling and Metabolic Transitions during Human Spermatogonial Stem Cell Development., Guo J, Grow EJ, Yi C, Mlcochova H, Maher GJ, Lindskog C, Murphy PJ, Wike CL, Carrell DT, Goriely A, Hotaling JM, Cairns BR., 2017

Areas of Focus

Molecular mechanisms of spermatogonial stem cell self-renewal and differentiation
In vivo and in vitro models for human spermatogonial stem cells
Molecular mechanisms of male infertility and new treatment methods

Publications

Single-cell multi-omics analysis of human testicular germ cell tumor reveals its molecular features and microenvironment., Lu X, Luo Y, Nie X, Zhang B, Wang X, Li R, Liu G, Zhou Q, Liu Z, Fan L, Hotaling JM, Zhang Z, Bo H, Guo J., 2023
Single-cell analysis of the developing human ovary defines distinct insights into ovarian somatic and germline progenitors., Wamaitha SE, Nie X, Pandolfi EC, Wang X, Yang Y, Stukenborg JB, Cairns BR, Guo J, Clark AT., 2023
Single-cell analysis of human testis aging and correlation with elevated body mass index., Nie X, Munyoki SK, Sukhwani M, Schmid N, Missel A, Emery BR, DonorConnect, Stukenborg JB, Mayerhofer A, Orwig KE, Aston KI, Hotaling JM, Cairns BR, Guo J., 2022
Comparative Single-Cell Analysis of Biopsies Clarifies Pathogenic Mechanisms in Klinefelter Syndrome., Mahyari E, Guo J, Lima AC, Vigh-Conrad KA, Nie X, Nagirnaja L, Rockweiler N, Carrell DT, Hotaling JM, Aston KI, Conrad DF., 2021
Single-Cell Analysis of the Developing Human Testis Reveals Somatic Niche Cell Specification and Fetal Germline Stem Cell Establishment., Guo J, Sosa E, Chitiashvili T, Nie X, Rojas EJ, Oliver E, DonorConnect, Hotaling JM, Stukenborg J, Clark AT, Cairns BR., 2021
NRF2 Loss Recapitulates Heritable Impacts of Paternal Cigarette Smoke Exposure., Murphy PJ, Guo J, Jenkins TG, James ER, Hoidal JR, Huecksteadt J, Hotaling JM, Carrell DT, Cairns BR, Aston KI., 2020
No Evidence of SARS-CoV-2 in Semen of Males Recovering from COVID-19., Pan F, Xiao X, Guo J, Song Y, Li H, Patel DP, Spivak AM, Alukal JP, Zhang X, Xiong C, Li PS, Hotaling JM., 2020
The Dynamic Transcriptional Cell Atlas of Testis Development During Human Puberty., Guo J, Nie X, Giebler M, Mlcochova H, Wang Y, Grow EJ, DonorConnect, Kim R, Tharmaligham M, Matilionyte G, Mitchell RT, Lindskog L, Carrell DT, Goriely A, Hotaling JM, Cairns BR., 2020
The Adult Human Testis Transcriptional Cell Atlas., Guo J, Grow EJ, Mlcochova H, Maher GJ, Lindskog C, Nie X, Guo Y, Takei Y, Yun J, Cai L, Kim R, Carrell DT, Goriely A, Hotaling JM, Cairns BR., 2018
Chromatin and Single-Cell RNA-seq Profiling Reveal Dynamic Signaling and Metabolic Transitions during Human Spermatogonial Stem Cell Development., Guo J, Grow EJ, Yi C, Mlcochova H, Maher GJ, Lindskog C, Murphy PJ, Wike CL, Carrell DT, Goriely A, Hotaling JM, Cairns BR., 2017

Spermatogenesis Stem Cells Molecular Biology Cell Biology High-Throughput Sequencing Male Infertility Testis Development Germ Cells Self-Renewal Differentiation

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