Professor | Min Chen | Asia Growth Partners

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Name	Min Chen
Contact Information	chenmin@ioz.ac.cn
Language ability	Chinese, English
Province	Beijing

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Name

Min Chen

Contact Information

chenmin@ioz.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Chinese Academy of Sciences
Faculty	Institute of Zoology
Academic Background & Achievements	2007 - PhD in Science: Institute of Zoology, Chinese Academy of Sciences
Work Experience	2011-2014 - Postdoctoral Research: Institute of Zoology, Chinese Academy of Sciences 2014-Present - Member of the Sex Determination and Differentiation Research Group: Institute of Zoology, Chinese Academy of Sciences 2022-Present - Associate Researcher: Institute of Zoology, Chinese Academy of Sciences

University/Lab Affiliation and Title

Chinese Academy of Sciences

Faculty

Institute of Zoology

Academic Background & Achievements

2007 - PhD in Science: Institute of Zoology, Chinese Academy of Sciences

Work Experience

2011-2014 - Postdoctoral Research: Institute of Zoology, Chinese Academy of Sciences
2014-Present - Member of the Sex Determination and Differentiation Research Group: Institute of Zoology, Chinese Academy of Sciences
2022-Present - Associate Researcher: Institute of Zoology, Chinese Academy of Sciences

Areas of Focus	Differentiation regulation of gonadal somatic and germ cells
Publications	PRMT5 regulates ovarian follicle development by facilitating Wt1 translation., Chen M, Dong F, Chen M, Shen Z, Wu H, Cen C, Cui X, Bao S, Gao F., 2021 Integration of single-cell transcriptome and chromatin accessibility of early gonads development among goats, pigs, macaques, and humans., Chen M, Long X, Chen M, Hao F, Kang J, Wang N, Wang Y, Wang M, Gao Y, Zhou M, et al., 2022 PRMT5 Is Involved in Spermatogonial Stem Cells Maintenance by Regulating Plzf Expression via Modulation of Lysine Histone Modifications., Dong F, Chen M, Chen M, Jiang L, Shen Z, Ma L, Han C, Guo X, Gao F., 2021 Abnormal Meiosis Initiation in Germ Cell Caused by Aberrant Differentiation of Gonad Somatic Cell., Chen M, Chen M, Chen S, Zhou J, Dong F, Shen Z, Wu H, Cui X, Gao F., 2019 Wt1 directs the lineage specification of sertoli and granulosa cells by repressing Sf1 expression., Chen M, Zhang L, Cui X, Lin X, Li Y, Wang Y, Wang Y, Qin Y, Chen D, Han C, Zhou B, Huff V, Gao F., 2017 Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation., Zhang L, Chen M, Wen Q, Li Y, Wang Y, Wang Y, Qin Y, Cui X, Yang L, Huff V, Gao F., 2015 Infection of SARS-CoV-2 causes severe pathological changes in mouse testis., Chen M, Li S, Liu S, Zhang Y, Cui X, Lv L, Liu B, Zheng A, Wang Q, Duo S, Gao F., 2023 The functions of Wt1 in mouse gonad development and somatic cells differentiation., Chen M, Cen C, Wang N, Shen Z, Wang M, Liu B, Li J, Cui X, Wang Y, Gao F., 2022 Inactivation of Wt1 causes pre-granulosa cell to steroidogenic cell transformation and defect of ovary development., Cen C, Chen M, Zhou J, Zhang L, Duo S, Jiang L, Hou X, Gao F., 2020 Wt1 is involved in leydig cell steroid hormone biosynthesis by regulating paracrine factor expression in mice., Chen M, Wang X, Wang Y, Zhang L, Xu B, Lv L, Cui X, Li W, Gao F., 2014 Epg5 deficiency leads to primary ovarian insufficiency due to WT1 accumulation in mouse granulosa cells., Liu W, Chen M, Liu C, Wang L, Wei H, Zhang R, Ren Z, Chen Y, Luo M, Zhao J, Jiang H, Gao F, Li W., 2022 The function of Foxo1 in spermatogonia development is independent of PI3K/PTEN signaling., Shen Z, Chen M, Gao Y, Dong F, Cen C, Wu H, Wang N, Cui X, Han C, Gao F., 2022 The Wilms tumor gene, Wt1, maintains testicular cord integrity by regulating the expression of Col4a1 and Col4a2., Chen SR, Chen M, Wang XN, Zhang J, Wen Q, Ji SY, Zheng QS, Gao F, Liu YX., 2013 Effect of heat stress on expression of junction-associated molecules and upstream factors androgen receptor and Wilms' tumor 1 in monkey sertoli cells., Chen M, Cai H, Yang JL, Lu CL, Liu T, Yang W, Guo J, Hu XQ, Fan CH, Hu ZY, Gao F, Liu YX., 2008 Effect of 43 degrees treatment on expression of heat shock proteins 105, 70 and 60 in cultured monkey Sertoli cells., Chen M, Yuan JX, Shi YQ, Zhang XS, Hu ZY, Gao F, Liu YX., 2008

Areas of Focus

Differentiation regulation of gonadal somatic and germ cells

Publications

PRMT5 regulates ovarian follicle development by facilitating Wt1 translation., Chen M, Dong F, Chen M, Shen Z, Wu H, Cen C, Cui X, Bao S, Gao F., 2021
Integration of single-cell transcriptome and chromatin accessibility of early gonads development among goats, pigs, macaques, and humans., Chen M, Long X, Chen M, Hao F, Kang J, Wang N, Wang Y, Wang M, Gao Y, Zhou M, et al., 2022
PRMT5 Is Involved in Spermatogonial Stem Cells Maintenance by Regulating Plzf Expression via Modulation of Lysine Histone Modifications., Dong F, Chen M, Chen M, Jiang L, Shen Z, Ma L, Han C, Guo X, Gao F., 2021
Abnormal Meiosis Initiation in Germ Cell Caused by Aberrant Differentiation of Gonad Somatic Cell., Chen M, Chen M, Chen S, Zhou J, Dong F, Shen Z, Wu H, Cui X, Gao F., 2019
Wt1 directs the lineage specification of sertoli and granulosa cells by repressing Sf1 expression., Chen M, Zhang L, Cui X, Lin X, Li Y, Wang Y, Wang Y, Qin Y, Chen D, Han C, Zhou B, Huff V, Gao F., 2017
Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation., Zhang L, Chen M, Wen Q, Li Y, Wang Y, Wang Y, Qin Y, Cui X, Yang L, Huff V, Gao F., 2015
Infection of SARS-CoV-2 causes severe pathological changes in mouse testis., Chen M, Li S, Liu S, Zhang Y, Cui X, Lv L, Liu B, Zheng A, Wang Q, Duo S, Gao F., 2023
The functions of Wt1 in mouse gonad development and somatic cells differentiation., Chen M, Cen C, Wang N, Shen Z, Wang M, Liu B, Li J, Cui X, Wang Y, Gao F., 2022
Inactivation of Wt1 causes pre-granulosa cell to steroidogenic cell transformation and defect of ovary development., Cen C, Chen M, Zhou J, Zhang L, Duo S, Jiang L, Hou X, Gao F., 2020
Wt1 is involved in leydig cell steroid hormone biosynthesis by regulating paracrine factor expression in mice., Chen M, Wang X, Wang Y, Zhang L, Xu B, Lv L, Cui X, Li W, Gao F., 2014
Epg5 deficiency leads to primary ovarian insufficiency due to WT1 accumulation in mouse granulosa cells., Liu W, Chen M, Liu C, Wang L, Wei H, Zhang R, Ren Z, Chen Y, Luo M, Zhao J, Jiang H, Gao F, Li W., 2022
The function of Foxo1 in spermatogonia development is independent of PI3K/PTEN signaling., Shen Z, Chen M, Gao Y, Dong F, Cen C, Wu H, Wang N, Cui X, Han C, Gao F., 2022
The Wilms tumor gene, Wt1, maintains testicular cord integrity by regulating the expression of Col4a1 and Col4a2., Chen SR, Chen M, Wang XN, Zhang J, Wen Q, Ji SY, Zheng QS, Gao F, Liu YX., 2013
Effect of heat stress on expression of junction-associated molecules and upstream factors androgen receptor and Wilms' tumor 1 in monkey sertoli cells., Chen M, Cai H, Yang JL, Lu CL, Liu T, Yang W, Guo J, Hu XQ, Fan CH, Hu ZY, Gao F, Liu YX., 2008
Effect of 43 degrees treatment on expression of heat shock proteins 105, 70 and 60 in cultured monkey Sertoli cells., Chen M, Yuan JX, Shi YQ, Zhang XS, Hu ZY, Gao F, Liu YX., 2008

Gonadal Somatic Cells Germ Cells Differentiation Regulation Sex Determination Cell Biology Reproductive Biology Stem Cells Developmental Biology

Gao Fei - Chinese Academy of Sciences

Jingtao Guo - Chinese Academy of Sciences

Jing Qu - Chinese Academy of Sciences

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