Professor | Mingsheng Cai | Asia Growth Partners

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Name	Mingsheng Cai
Contact Information	108629274@qq.com
Language ability	Chinese, English
Province	Guangdong

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Name

Mingsheng Cai

Contact Information

108629274@qq.com

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Guangzhou Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	PhD: Wuhan Institute of Virology, Chinese Academy of Sciences
Awards	Guangdong Medical Science and Technology Award Second Prize Outstanding Young Innovative Talent in Guangdong Universities High-level Talent in Guangzhou Nanshan Scholar of Guangzhou Medical University Academic Backbone of High-level University at Guangzhou Medical University

University/Lab Affiliation and Title

Guangzhou Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

PhD: Wuhan Institute of Virology, Chinese Academy of Sciences

Awards

Guangdong Medical Science and Technology Award Second Prize
Outstanding Young Innovative Talent in Guangdong Universities
High-level Talent in Guangzhou
Nanshan Scholar of Guangzhou Medical University
Academic Backbone of High-level University at Guangzhou Medical University

Areas of Focus	Herpesvirus infection and host innate immunity Regulatory mechanisms of host innate immunity Relationship between EB virus infection and tumor development Herpesvirus vaccine development Antiviral drug development and mechanism research Mechanism and application of oncolytic viruses Subcellular transport mechanisms and functions of viral proteins Tumor immunity, anti-tumor drug/vaccine research
Publications	Epstein-Barr virus envelope glycoprotein 110 inhibits NF-κB activation by interacting with NF-κB subunit p65., Cai MS, Xiao B, Wang YF, Wang KZ, Luo WQ, Fu JQ, Wang S, Deng SY, Li BL, Gong L, Zhong JY, Hu L, Pan LX, Wang LD, Liu YT, Huang C, Li XQ, Zeng QY, Kang HR, Li LH, Zan J(), Peng T(), Yang HD(), Li ML(), 2023 Epstein-Barr virus envelope glycoprotein gp110 inhibits IKKi-mediated activation of NF-κB and promotes the degradation of β-catenin., Guo YJ, Pan LX, Wang LD, Wang S, Fu JQ, Luo WQ, Wang KZ, Li XQ, Huang C, Liu YT, Kang HR, Zeng QY, Fu XX, Huang ZJ, Li WY, He YX, Li LH, Peng T, Yang HD(), Li ML(), Xiao B(), Cai MS(), 2023 The molecular mechanism of herpes simplex virus 1 UL31 in antagonizing the activity of IFN-β., Gong L, Ou XW, Hu L, Zhong JY, Li JJ, Deng SY, Li BL, Pan LX, Wang LD, Hong XJ, Luo WQ, Zeng QY, Zan J, Peng T(), Cai MS(), Li ML(), 2022 Epstein-Barr virus tegument protein BGLF2 inhibits NF-κB activity by preventing p65 Ser536 phosphorylation., Chen T, Wang YF, Xu Z, Zou XM, Wang P, Ou XW, Li YW, Peng T, Chen DX, Li ML(), Cai MS(), 2019 Subcellular localization of Epstein-Barr virus BLLF2 and its underlying mechanisms., Li JJ, Guo YJ, Deng YX, Hu L, Li BL, Deng SY, Zhong JY, Xie L, Shi SX, Hong XJ, Zheng XL, Cai MS(), Li ML(), 2021 Herpes simplex virus 1 UL2 inhibits the TNF-α-mediated NF-κB activity by interacting with p65/p50., Cai MS, Liao ZM, Zou XM, Xu Z, Wang YF, Li T, Li YW, Ou XW, Deng YX, Guo YJ, Peng T, Li ML(), 2020 Epstein-Barr virus early protein BFRF1 suppresses IFN-β activity by inhibiting the activation of IRF3., Wang P, Deng YX, Guo YJ, Xu Z, Li YW, Ou XW, Xie L, Lu MJ, Zhong JY, Li BL, Hu L, Deng SY, Peng T, Cai MS(), Li ML(), 2020 The interaction mechanism between herpes simplex virus 1 glycoprotein D and host antiviral protein viperin., Li ML, Liao ZM, Xu Z, Zou XM, Wang YF, Peng H, Li YW, Ou XW, Deng YX, Guo YJ, Gan WD, Peng T, Chen DX, Cai MS(), 2019 Herpesviral infection and Toll-like receptor 2., Cai MS, Li ML, Zheng CF(), 2012 The herpes simplex virus 1-encoded envelope glycoprotein B activates NF-κB through the Toll-like receptor 2 and MyD88/TRAF6-dependent signaling pathway., Cai MS, Li ML, Wang KZ, Wang S, Lu Q, Yan JH, Mossman KL, Lin RT, Zheng CF(), 2013 Comparison of the immune responses in BALB/c Mice following immunization with DNA-based and live attenuated vaccines delivered via different routes., Cai MS, Deng SX, Li ML(), 2013 Probing the nuclear import signal and nuclear transport molecular determinants of PRV ICP22., Cai MS, Jiang S, Zeng ZC, Li XW, Mo CC, Yang YJ, Chen CK, Xie PP, Bian Y, Wang JL, Huang JL, Chen DX, Peng T, Li ML(), 2016 Characterization of the nuclear import and export signals, and subcellular transport mechanism of varicella-zoster virus ORF9., Cai MS, Wang S, Xing JJ, Zheng CF(), 2011 Probing of the nuclear import and export signals and subcellular transport mechanism of varicella-zoster virus tegument protein open reading frame 10., Cai MS, Wang S, Long J, Zheng CF(), 2012 Identification of molecular determinants for the nuclear import of pseudorabies virus UL31., Li ML, Jiang S, Mo CC, Wang JL, Huang JL, Zeng ZC, Li XW, Chen CK, Yang YJ, Peng T, Cai MS(), 2015 Molecular property of the Epstein-Barr virus BFRF3 gene., Cai MS, Zhao ZY, Yang L, Zhu JY, Cui W, Ma CL, Yuan ZQ, Li ML(), 2013 Characterization of synonymous codon usage bias in the pseudorabies virus US1 gene., Li ML, Zhao ZY, Chen JH, Wang BY, Li Z, Li J, Cai MS(), 2012

Areas of Focus

Herpesvirus infection and host innate immunity
Regulatory mechanisms of host innate immunity
Relationship between EB virus infection and tumor development
Herpesvirus vaccine development
Antiviral drug development and mechanism research
Mechanism and application of oncolytic viruses
Subcellular transport mechanisms and functions of viral proteins
Tumor immunity, anti-tumor drug/vaccine research

Publications

Epstein-Barr virus envelope glycoprotein 110 inhibits NF-κB activation by interacting with NF-κB subunit p65., Cai MS, Xiao B, Wang YF, Wang KZ, Luo WQ, Fu JQ, Wang S, Deng SY, Li BL, Gong L, Zhong JY, Hu L, Pan LX, Wang LD, Liu YT, Huang C, Li XQ, Zeng QY, Kang HR, Li LH, Zan J(*), Peng T(*), Yang HD(*), Li ML(*), 2023
Epstein-Barr virus envelope glycoprotein gp110 inhibits IKKi-mediated activation of NF-κB and promotes the degradation of β-catenin., Guo YJ, Pan LX, Wang LD, Wang S, Fu JQ, Luo WQ, Wang KZ, Li XQ, Huang C, Liu YT, Kang HR, Zeng QY, Fu XX, Huang ZJ, Li WY, He YX, Li LH, Peng T, Yang HD(*), Li ML(*), Xiao B(*), Cai MS(*), 2023
The molecular mechanism of herpes simplex virus 1 UL31 in antagonizing the activity of IFN-β., Gong L, Ou XW, Hu L, Zhong JY, Li JJ, Deng SY, Li BL, Pan LX, Wang LD, Hong XJ, Luo WQ, Zeng QY, Zan J, Peng T(*), Cai MS(*), Li ML(*), 2022
Epstein-Barr virus tegument protein BGLF2 inhibits NF-κB activity by preventing p65 Ser536 phosphorylation., Chen T, Wang YF, Xu Z, Zou XM, Wang P, Ou XW, Li YW, Peng T, Chen DX, Li ML(*), Cai MS(*), 2019
Subcellular localization of Epstein-Barr virus BLLF2 and its underlying mechanisms., Li JJ, Guo YJ, Deng YX, Hu L, Li BL, Deng SY, Zhong JY, Xie L, Shi SX, Hong XJ, Zheng XL, Cai MS(*), Li ML(*), 2021
Herpes simplex virus 1 UL2 inhibits the TNF-α-mediated NF-κB activity by interacting with p65/p50., Cai MS, Liao ZM, Zou XM, Xu Z, Wang YF, Li T, Li YW, Ou XW, Deng YX, Guo YJ, Peng T, Li ML(*), 2020
Epstein-Barr virus early protein BFRF1 suppresses IFN-β activity by inhibiting the activation of IRF3., Wang P, Deng YX, Guo YJ, Xu Z, Li YW, Ou XW, Xie L, Lu MJ, Zhong JY, Li BL, Hu L, Deng SY, Peng T, Cai MS(*), Li ML(*), 2020
The interaction mechanism between herpes simplex virus 1 glycoprotein D and host antiviral protein viperin., Li ML, Liao ZM, Xu Z, Zou XM, Wang YF, Peng H, Li YW, Ou XW, Deng YX, Guo YJ, Gan WD, Peng T, Chen DX, Cai MS(*), 2019
Herpesviral infection and Toll-like receptor 2., Cai MS, Li ML, Zheng CF(*), 2012
The herpes simplex virus 1-encoded envelope glycoprotein B activates NF-κB through the Toll-like receptor 2 and MyD88/TRAF6-dependent signaling pathway., Cai MS, Li ML, Wang KZ, Wang S, Lu Q, Yan JH, Mossman KL, Lin RT, Zheng CF(*), 2013
Comparison of the immune responses in BALB/c Mice following immunization with DNA-based and live attenuated vaccines delivered via different routes., Cai MS, Deng SX, Li ML(*), 2013
Probing the nuclear import signal and nuclear transport molecular determinants of PRV ICP22., Cai MS, Jiang S, Zeng ZC, Li XW, Mo CC, Yang YJ, Chen CK, Xie PP, Bian Y, Wang JL, Huang JL, Chen DX, Peng T, Li ML(*), 2016
Characterization of the nuclear import and export signals, and subcellular transport mechanism of varicella-zoster virus ORF9., Cai MS, Wang S, Xing JJ, Zheng CF(*), 2011
Probing of the nuclear import and export signals and subcellular transport mechanism of varicella-zoster virus tegument protein open reading frame 10., Cai MS, Wang S, Long J, Zheng CF(*), 2012
Identification of molecular determinants for the nuclear import of pseudorabies virus UL31., Li ML, Jiang S, Mo CC, Wang JL, Huang JL, Zeng ZC, Li XW, Chen CK, Yang YJ, Peng T, Cai MS(*), 2015
Molecular property of the Epstein-Barr virus BFRF3 gene., Cai MS, Zhao ZY, Yang L, Zhu JY, Cui W, Ma CL, Yuan ZQ, Li ML(*), 2013
Characterization of synonymous codon usage bias in the pseudorabies virus US1 gene., Li ML, Zhao ZY, Chen JH, Wang BY, Li Z, Li J, Cai MS(*), 2012

Herpesvirus Innate Immunity Eb Virus Tumor Development Vaccine Development Antiviral Drugs Oncolytic Viruses Subcellular Transport Viral Proteins Tumor Immunity

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