Professor | 蔡铭升 | 数字化转型顾问

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Name	蔡铭升
Contact Information	108629274@qq.com
Language ability	中文, 英语
Province	广东

Upload Avatar (500 x 500)

Name

蔡铭升

Contact Information

108629274@qq.com

Language ability

中文, 英语

Province

广东

University/Lab Affiliation and Title	广州医科大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	博士: 中国科学院武汉病毒研究所
Awards	广东医学科技奖二等奖广东高校优秀青年创新人才广州市高层次人才广州医科大学“南山学者” 广州医科大学高水平大学学术骨干

University/Lab Affiliation and Title

广州医科大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

博士: 中国科学院武汉病毒研究所

Awards

广东医学科技奖二等奖
广东高校优秀青年创新人才
广州市高层次人才
广州医科大学“南山学者”
广州医科大学高水平大学学术骨干

Areas of Focus	疱疹病毒感染与宿主天然免疫宿主天然免疫调控机制研究 EB病毒感染与肿瘤发生发展的关系疱疹病毒疫苗研制抗疱疹病毒药物研发与作用机制研究溶瘤病毒的作用机制与应用病毒蛋白亚细胞转运转运机制及功能研究肿瘤免疫、抗肿瘤药物/疫苗研究
Publications	Epstein-Barr virus envelope glycoprotein 110 inhibits NF-κB activation by interacting with NF-κB subunit p65., Cai MS, Xiao B, Wang YF, Wang KZ, Luo WQ, Fu JQ, Wang S, Deng SY, Li BL, Gong L, Zhong JY, Hu L, Pan LX, Wang LD, Liu YT, Huang C, Li XQ, Zeng QY, Kang HR, Li LH, Zan J(), Peng T(), Yang HD(), Li ML(), 2023 Epstein-Barr virus envelope glycoprotein gp110 inhibits IKKi-mediated activation of NF-κB and promotes the degradation of β-catenin., Guo YJ, Pan LX, Wang LD, Wang S, Fu JQ, Luo WQ, Wang KZ, Li XQ, Huang C, Liu YT, Kang HR, Zeng QY, Fu XX, Huang ZJ, Li WY, He YX, Li LH, Peng T, Yang HD(), Li ML(), Xiao B(), Cai MS(), 2023 The molecular mechanism of herpes simplex virus 1 UL31 in antagonizing the activity of IFN-β., Gong L, Ou XW, Hu L, Zhong JY, Li JJ, Deng SY, Li BL, Pan LX, Wang LD, Hong XJ, Luo WQ, Zeng QY, Zan J, Peng T(), Cai MS(), Li ML(), 2022 Epstein-Barr virus tegument protein BGLF2 inhibits NF-κB activity by preventing p65 Ser536 phosphorylation., Chen T, Wang YF, Xu Z, Zou XM, Wang P, Ou XW, Li YW, Peng T, Chen DX, Li ML(), Cai MS(), 2019 Subcellular localization of Epstein-Barr virus BLLF2 and its underlying mechanisms., Li JJ, Guo YJ, Deng YX, Hu L, Li BL, Deng SY, Zhong JY, Xie L, Shi SX, Hong XJ, Zheng XL, Cai MS(), Li ML(), 2021 Herpes simplex virus 1 UL2 inhibits the TNF-α-mediated NF-κB activity by interacting with p65/p50., Cai MS, Liao ZM, Zou XM, Xu Z, Wang YF, Li T, Li YW, Ou XW, Deng YX, Guo YJ, Peng T, Li ML(), 2020 Epstein-Barr virus early protein BFRF1 suppresses IFN-β activity by inhibiting the activation of IRF3., Wang P, Deng YX, Guo YJ, Xu Z, Li YW, Ou XW, Xie L, Lu MJ, Zhong JY, Li BL, Hu L, Deng SY, Peng T, Cai MS(), Li ML(), 2020 The interaction mechanism between herpes simplex virus 1 glycoprotein D and host antiviral protein viperin., Li ML, Liao ZM, Xu Z, Zou XM, Wang YF, Peng H, Li YW, Ou XW, Deng YX, Guo YJ, Gan WD, Peng T, Chen DX, Cai MS(), 2019 Herpesviral infection and Toll-like receptor 2., Cai MS, Li ML, Zheng CF(), 2012 The herpes simplex virus 1-encoded envelope glycoprotein B activates NF-κB through the Toll-like receptor 2 and MyD88/TRAF6-dependent signaling pathway., Cai MS, Li ML, Wang KZ, Wang S, Lu Q, Yan JH, Mossman KL, Lin RT, Zheng CF(), 2013 Comparison of the immune responses in BALB/c Mice following immunization with DNA-based and live attenuated vaccines delivered via different routes., Cai MS, Deng SX, Li ML(), 2013 Probing the nuclear import signal and nuclear transport molecular determinants of PRV ICP22., Cai MS, Jiang S, Zeng ZC, Li XW, Mo CC, Yang YJ, Chen CK, Xie PP, Bian Y, Wang JL, Huang JL, Chen DX, Peng T, Li ML(), 2016 Characterization of the nuclear import and export signals, and subcellular transport mechanism of varicella-zoster virus ORF9., Cai MS, Wang S, Xing JJ, Zheng CF(), 2011 Probing of the nuclear import and export signals and subcellular transport mechanism of varicella-zoster virus tegument protein open reading frame 10., Cai MS, Wang S, Long J, Zheng CF(), 2012 Identification of molecular determinants for the nuclear import of pseudorabies virus UL31., Li ML, Jiang S, Mo CC, Wang JL, Huang JL, Zeng ZC, Li XW, Chen CK, Yang YJ, Peng T, Cai MS(), 2015 Molecular property of the Epstein-Barr virus BFRF3 gene., Cai MS, Zhao ZY, Yang L, Zhu JY, Cui W, Ma CL, Yuan ZQ, Li ML(), 2013 Characterization of synonymous codon usage bias in the pseudorabies virus US1 gene., Li ML, Zhao ZY, Chen JH, Wang BY, Li Z, Li J, Cai MS(), 2012

Areas of Focus

疱疹病毒感染与宿主天然免疫
宿主天然免疫调控机制研究
EB病毒感染与肿瘤发生发展的关系
疱疹病毒疫苗研制
抗疱疹病毒药物研发与作用机制研究
溶瘤病毒的作用机制与应用
病毒蛋白亚细胞转运转运机制及功能研究
肿瘤免疫、抗肿瘤药物/疫苗研究

Publications

Epstein-Barr virus envelope glycoprotein 110 inhibits NF-κB activation by interacting with NF-κB subunit p65., Cai MS, Xiao B, Wang YF, Wang KZ, Luo WQ, Fu JQ, Wang S, Deng SY, Li BL, Gong L, Zhong JY, Hu L, Pan LX, Wang LD, Liu YT, Huang C, Li XQ, Zeng QY, Kang HR, Li LH, Zan J(*), Peng T(*), Yang HD(*), Li ML(*), 2023
Epstein-Barr virus envelope glycoprotein gp110 inhibits IKKi-mediated activation of NF-κB and promotes the degradation of β-catenin., Guo YJ, Pan LX, Wang LD, Wang S, Fu JQ, Luo WQ, Wang KZ, Li XQ, Huang C, Liu YT, Kang HR, Zeng QY, Fu XX, Huang ZJ, Li WY, He YX, Li LH, Peng T, Yang HD(*), Li ML(*), Xiao B(*), Cai MS(*), 2023
The molecular mechanism of herpes simplex virus 1 UL31 in antagonizing the activity of IFN-β., Gong L, Ou XW, Hu L, Zhong JY, Li JJ, Deng SY, Li BL, Pan LX, Wang LD, Hong XJ, Luo WQ, Zeng QY, Zan J, Peng T(*), Cai MS(*), Li ML(*), 2022
Epstein-Barr virus tegument protein BGLF2 inhibits NF-κB activity by preventing p65 Ser536 phosphorylation., Chen T, Wang YF, Xu Z, Zou XM, Wang P, Ou XW, Li YW, Peng T, Chen DX, Li ML(*), Cai MS(*), 2019
Subcellular localization of Epstein-Barr virus BLLF2 and its underlying mechanisms., Li JJ, Guo YJ, Deng YX, Hu L, Li BL, Deng SY, Zhong JY, Xie L, Shi SX, Hong XJ, Zheng XL, Cai MS(*), Li ML(*), 2021
Herpes simplex virus 1 UL2 inhibits the TNF-α-mediated NF-κB activity by interacting with p65/p50., Cai MS, Liao ZM, Zou XM, Xu Z, Wang YF, Li T, Li YW, Ou XW, Deng YX, Guo YJ, Peng T, Li ML(*), 2020
Epstein-Barr virus early protein BFRF1 suppresses IFN-β activity by inhibiting the activation of IRF3., Wang P, Deng YX, Guo YJ, Xu Z, Li YW, Ou XW, Xie L, Lu MJ, Zhong JY, Li BL, Hu L, Deng SY, Peng T, Cai MS(*), Li ML(*), 2020
The interaction mechanism between herpes simplex virus 1 glycoprotein D and host antiviral protein viperin., Li ML, Liao ZM, Xu Z, Zou XM, Wang YF, Peng H, Li YW, Ou XW, Deng YX, Guo YJ, Gan WD, Peng T, Chen DX, Cai MS(*), 2019
Herpesviral infection and Toll-like receptor 2., Cai MS, Li ML, Zheng CF(*), 2012
The herpes simplex virus 1-encoded envelope glycoprotein B activates NF-κB through the Toll-like receptor 2 and MyD88/TRAF6-dependent signaling pathway., Cai MS, Li ML, Wang KZ, Wang S, Lu Q, Yan JH, Mossman KL, Lin RT, Zheng CF(*), 2013
Comparison of the immune responses in BALB/c Mice following immunization with DNA-based and live attenuated vaccines delivered via different routes., Cai MS, Deng SX, Li ML(*), 2013
Probing the nuclear import signal and nuclear transport molecular determinants of PRV ICP22., Cai MS, Jiang S, Zeng ZC, Li XW, Mo CC, Yang YJ, Chen CK, Xie PP, Bian Y, Wang JL, Huang JL, Chen DX, Peng T, Li ML(*), 2016
Characterization of the nuclear import and export signals, and subcellular transport mechanism of varicella-zoster virus ORF9., Cai MS, Wang S, Xing JJ, Zheng CF(*), 2011
Probing of the nuclear import and export signals and subcellular transport mechanism of varicella-zoster virus tegument protein open reading frame 10., Cai MS, Wang S, Long J, Zheng CF(*), 2012
Identification of molecular determinants for the nuclear import of pseudorabies virus UL31., Li ML, Jiang S, Mo CC, Wang JL, Huang JL, Zeng ZC, Li XW, Chen CK, Yang YJ, Peng T, Cai MS(*), 2015
Molecular property of the Epstein-Barr virus BFRF3 gene., Cai MS, Zhao ZY, Yang L, Zhu JY, Cui W, Ma CL, Yuan ZQ, Li ML(*), 2013
Characterization of synonymous codon usage bias in the pseudorabies virus US1 gene., Li ML, Zhao ZY, Chen JH, Wang BY, Li Z, Li J, Cai MS(*), 2012

疱疹病毒天然免疫 Eb病毒肿瘤发展疫苗开发抗病毒药物溶瘤病毒亚细胞转运病毒蛋白肿瘤免疫

李美丽 - 广州医科大学

王晓健 - 浙江大学

束敏峰 - 复旦大学

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