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Feng Du
Basic Medical Sciences
Guangzhou Medical University
Guangdong
Language: Chinese, English
Mitochondria
Autophagy
Cellular Stress
Neurodegenerative Diseases
Cancer
Oxidative Stress
Signal Transduction
Calcium Homeostasis
Cell Death
Aging
Areas of Focus
- Mitochondrial Autophagy
Academic Background & Achievements
- PhD: Tsinghua University
- Postdoctoral: Harvard University
Publications
- Prohibitin 1 regulates mtDNA release and downstream inflammatory responses., Liu H, Fan H, He P, Zhuang H, Liu X, Chen M, Zhong W, Zhang Y, Zhen C, Li Y, Jiang H, Meng T, Xu Y, Zhao G, Feng D, 2022
- ATP9A Deficiency Causes ADHD and Aberrant Endosomal Recycling via Modulating RAB5 and RAB11 Activity., Meng T, Chen XT, He ZJ, Huang HF, Lin SY, Liu KR, Bai G, Xu MD, Zhuang HX, Zhang YL, Waqas A, Liu Q, Zhang C, Sun XD, Huang HS, Umair M, Yan YS, Feng D, 2023
- The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses., Hu Y, Chen H, Zhang L, Lin X, Li X, Zhuang H, Fan H, Meng T, He Z, Huang H, Gong Q, Zhu D, Xu Y, He P, Li L, Feng D, 2021
- Autophagy as a novel therapeutic target in vascular calcification., Phadwal K, Feng D, Zhu D, MacRae VE, 2019
- FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions., Wu W, Lin C, Wu K, Jiang L, Wang X, Li W, Zhuang H, Zhang X, Chen H, Li S, Yang Y, Lu Y, Wang J, Zhu R, Zhang L, Sui S, Tan N, Zhao B, Zhang J, Li L, Feng D, 2016
- ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy., Wu W, Tian W, Hu Z, Chen G, Huang L, Li W, Zhang X, Xue P, Zhou C, Liu L, Zhu Y, Zhang X, Li L, Zhang L, Sui S, Zhao B, Feng D, 2014
- The Release of Peripheral Immune Inflammatory Cytokines Promote an Inflammatory Cascade in PCOS Patients via Altering the Follicular Microenvironment., Liu Y, Liu H, Li Z, Fan H, Yan X, Liu X, Xuan J, Feng D, Wei X, 2021
- MicroRNA-137 is a Novel Hypoxia-responsive MicroRNA that Inhibis Mitophagy via Regulation of Two Mitophagy Receptors FUNDC1 and NIX., Li W, Zhang X, Zhuang H, Chen HG, Chen Y, Tian W, Wu W, Li Y, Wang S, Zhang L, Chen Y, Li L, Zhao B, Sui S, Hu Z, Feng D, 2014
- Mitochondrial outer membrane protein FUNDC1 mediates hypoxia-induced mitochondrial autophagy in mammalian cells., Liu L, Feng D, Chen G, Chen M, Zheng Q, Song P, Ma Q, Zhu C, Wang R, Qi W, Huang L, Xue P, Li B, Wang X, Jin H, Wang J, Yang F, Liu P, Zhu Y, Sui SF, Chen Q, 2012
- Molecular machineries and physiological relevance of ER-mediated membrane contacts., Lin S, Meng T, Huang H, Zhuang H, He Z, Yang H, Feng D, 2021
- Selective autophagy of intracellular organelles: recent research advances., Li W, He P, Huang Y, Li YF, Lu J, Li M, Kurihara H, Luo Z, Meng T, Onishi M, Ma C, Jiang L, Hu Y, Gong Q, Zhu D, Xu Y, Liu R, Liu L, Yi C, Zhu Y, Ma N, Okamoto K, Xie Z, Liu J, He RR, Feng D, 2021
- Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy., Tian W, Li W, Chen Y, Yan Z, Huang X, Zhuang H, Zhong W, Chen Y, Wu W, Lin C, Chen H, Hou X, Zhang L, Sui S, Zhao B, Hu Z, Li L, Feng D, 2015
- Differential MicroRNA Profiling in a Cellular Hypoxia Reoxygenation Model upon Posthypoxic Propofol Treatment Reveals Alterations in Autophagy Signaling Network., Chen Z, Hu Z, Lu Z, Cai S, Gu X, Zhuang H, Ruan Z, Xia Z, Irwin MG, Feng D, Zhang L, 2013
- Cellular internalization of exosomes occurs through phagocytosis., Feng D, Zhao WL, Ye YY, Bai XC, Chang LF, Zhou Q, Sui SF, 2010
- MicroRNA-495 regulates starvation-induced autophagy by targeting ATG3., Li W, Yang Y, Hou X, Zhuang H, Wu Z, Li Z, Guo R, Chen H, Lin C, Zhong W, Chen Y, Wu K, Zhang L, Feng D, 2016
- MicroRNA-93 Regulates Hypoxia-Induced Autophagy by Targeting ULK1., Li W, Yang Y, Ba Z, Li S, Chen H, Hou X, Ma L, He P, Jiang L, Li L, He R, Zhang L, Feng D, 2017
- Molecular Signaling towards mitophagy and its physiological significance., Feng D, Liu L, Zhu Y, Chen Q, 2013
- Autophagic Cell Death and Apoptosis Jointly Mediate Cisatracurium Besylate-Induced Cell Injury., Zhuang H, Tian W, Li W, Zhang X, Wang J, Yang Y, Liu X, Xia Z, Feng D, Zhang L, 2016
- A novel strategy for the invasive toxin: hijacking exosome-mediated intercellular trafficking., Zhang F, Sun S, Feng D, Zhao WL, Sui SF, 2009
- Autophagy Induced by Proteasomal DUB Inhibitor NiPT Restricts NiPT-Mediated Cancer Cell Death., Chen J, Chen X, Xu D, Yang L, Yang Z, Yang Q, Yan D, Zhang P, Feng D, Liu J, 2020
- Mitochondrial Quality Control in Cardiomyocytes: A Critical Role in the Progression of Cardiovascular Diseases., Fan H, He Z, Huang H, Zhuang H, Liu H, Liu X, Yang S, He P, Yang H, Feng D, 2020
Awards
- 2018: Selected as Guangdong Province 'Pearl River Scholar' Distinguished Professor
- 2019: Selected as Guangzhou Outstanding Expert
- 2015: Selected as Guangdong Province 'Sailing Plan' Top Talent
