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Liao Yuning
Basic Medical Sciences
Guangzhou Medical University
Guangdong
Language: Chinese, English
Post-Translational Modification
Cancer
Usp1
Uaf1
Rps16
Ubiquitination
Degradation
Liver Cancer
Malignant Progression
Protein Stability
Areas of Focus
- Post-translational modification and cancer
Academic Background & Achievements
- PhD: Guangzhou Medical University
Publications
- USP10 modulates the SKP2/Bcr-Abl axis via stabilizing SKP2 in chronic myeloid leukemia., Liao Y, Liu N, Xia X, Guo Z, Li Y, Jiang L, Zhou R, Tang D, Huang H, Liu J, 2019
- USP1-dependent RPS16 protein stability drives growth and metastasis of human hepatocellular carcinoma cells., Liao Y, Shao Z, Liu Y, Xia X, Deng Y, Yu C, Sun W, Kong W, He X, Liu F, Guo Z, Chen G, Tang D, Gan H, Liu J, Huang H, 2021
- A new role of GRP75-USP1-SIX1 protein complex in driving prostate cancer progression and castration resistance., Liao Y, Liu Y, Shao Z, Xia X, Deng Y, Cai J, Yao L, He J, Yu C, Hu T, Sun W, Liu F, Tang D, Liu J, Huang H, 2021
- Targeting GRP78-dependent AR-V7 protein degradation overcomes castration-resistance in prostate cancer therapy., Liao Y, Liu Y, Xia X, Shao Z, Huang C, He J, Jiang L, Tang D, Liu J, Huang H, 2020
- Inhibition of EGFR signaling with Spautin-1 represents a novel therapeutics for prostate cancer., Liao Y, Guo Z, Xia X, Liu Y, Huang C, Jiang L, Wang X, Liu J, Huang H, 2019
- Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination., Liao Y, Xia X, Liu N, Cai J, Guo Z, Li Y, Jiang L, Dou Q, Tang D, Huang H, Liu J, 2018
- Proteasome-associated deubiquitinase ubiquitin-specific protease 14 regulates prostate cancer proliferation by deubiquitinating and stabilizing androgen receptor., Liao Y, Liu N, Hua X, Cai J, Xia X, Wang X, Huang H, Liu J, 2017
- A SIX1 degradation inducer blocks excessive proliferation of prostate cancer., Liao Y, Sun W, Shao Z, Liu Y, Zhong X, Deng Y, Liu F, Huang H, Liu J, 2022
- SNS-023 sensitizes hepatocellular carcinoma to sorafenib by inducing degradation of cancer drivers SIX1 and RPS16., Liu Y, Kong W, Yu, C, Shao Z, Lei Q, Deng Y, Cai G, Zhuang X, Sun W, Wu S, Wang R, Chen X, Chen G, Huang H, Liao Y, 2022
- Selective degradation of AR-V7 to overcome castration resistance of prostate cancer., Liu Y, Yu C, Shao Z, Xia X, Hu T, Kong W, He X, Sun W, Deng Y, Liao Y, Huang H, 2021
