Professor | Yuanyuan Ruan | Asia Growth Partners

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Name	Yuanyuan Ruan
Contact Information	nyuanyuanruan@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Yuanyuan Ruan

Contact Information

nyuanyuanruan@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2000.09—2005.06 Bachelor's Degree in Forensic Medicine: Fudan University Shanghai Medical College 2005.09—2010.06 Ph.D. in Biochemistry and Molecular Biology: Fudan University Shanghai Medical College
Work Experience	2010.07—2012.09 - Fudan University - Postdoctoral Researcher in Basic Medicine 2012.09—2013.12 - Fudan University - Lecturer in Basic Medicine 2013.12—2018.12 - Fudan University - Associate Researcher in Basic Medicine 2018.12—Present - Fudan University - Professor in Basic Medicine
Awards	2019: Zhongying Young Scholar, Fudan University 2015: Outstanding Postdoctoral Fellow, Fudan University

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2000.09—2005.06 Bachelor's Degree in Forensic Medicine: Fudan University Shanghai Medical College
2005.09—2010.06 Ph.D. in Biochemistry and Molecular Biology: Fudan University Shanghai Medical College

Work Experience

2010.07—2012.09 - Fudan University - Postdoctoral Researcher in Basic Medicine
2012.09—2013.12 - Fudan University - Lecturer in Basic Medicine
2013.12—2018.12 - Fudan University - Associate Researcher in Basic Medicine
2018.12—Present - Fudan University - Professor in Basic Medicine

Awards

2019: Zhongying Young Scholar, Fudan University
2015: Outstanding Postdoctoral Fellow, Fudan University

Areas of Focus	Post-translational modification of proteins (glycosylation) and tumorigenesis Tumor-related signal transduction and abnormal protein translation Mechanisms and intervention strategies for precancerous lesions of digestive system tumors
Publications	Reticulon 3-mediated Chk2/p53 activation suppresses hepatocellular carcinogenesis and is blocked by hepatitis B virus., Song S, Shi Y, Wu W, Wu H, Chang L, Peng P, Zhang L, Fan J, Gu J, Ruan Y, 2021 O-GlcNAcylation of RACK1 promotes hepatocellular carcinogenesis., Duan F, Wu H, Jia D, Wu W, Ren S, Wang L, Song S, Guo X, Liu F, Ruan Y, Gu J, 2018 C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits., Wang L#, Yin J#, Wang X#, Shao M, Duan F, Wu W, Peng P, Jin J, Tang Y, Ruan Y, Sun Y, Gu J, 2016 Loss of RACK1 Promotes Metastasis of Gastric Cancer by Inducing a miR-302c/IL8 Signaling Loop., Chen L#, Min L#, Wang X#, Zhao J, Chen H, Qin J, Chen W, Shen Z, Tang Z, Gan Q, Ruan Y, Sun Y, Qin X, Gu J, 2015 Ribosomal RACK1 promotes chemoresistance and growth in human hepatocellular carcinoma., Ruan Y, Sun L, Hao Y, Wang L, Xu J, Zhang W, Xie J, Guo L, Zhou L, Yun X, Zhu H, Shen A, Gu J, 2012

Areas of Focus

Post-translational modification of proteins (glycosylation) and tumorigenesis
Tumor-related signal transduction and abnormal protein translation
Mechanisms and intervention strategies for precancerous lesions of digestive system tumors

Publications

Reticulon 3-mediated Chk2/p53 activation suppresses hepatocellular carcinogenesis and is blocked by hepatitis B virus., Song S, Shi Y, Wu W, Wu H, Chang L, Peng P, Zhang L, Fan J, Gu J, Ruan Y*, 2021
O-GlcNAcylation of RACK1 promotes hepatocellular carcinogenesis., Duan F, Wu H, Jia D, Wu W, Ren S, Wang L, Song S, Guo X, Liu F*, Ruan Y*, Gu J, 2018
C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits., Wang L#, Yin J#, Wang X#, Shao M, Duan F, Wu W, Peng P, Jin J, Tang Y, Ruan Y*, Sun Y*, Gu J*, 2016
Loss of RACK1 Promotes Metastasis of Gastric Cancer by Inducing a miR-302c/IL8 Signaling Loop., Chen L#, Min L#, Wang X#, Zhao J, Chen H, Qin J, Chen W, Shen Z, Tang Z, Gan Q, Ruan Y*, Sun Y*, Qin X*, Gu J, 2015
Ribosomal RACK1 promotes chemoresistance and growth in human hepatocellular carcinoma., Ruan Y, Sun L, Hao Y, Wang L, Xu J, Zhang W, Xie J, Guo L, Zhou L, Yun X, Zhu H, Shen A, Gu J*, 2012

Glycosylation Tumorigenesis Signal Transduction Protein Translation Precancerous Lesions Digestive System Intervention Strategies Post-Translational Modification Cancer Biochemistry

Xiaowei Zhang - Peking University

Weibin Wang - Peking University

Yan Luo - Zhejiang University

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