Areas of Focus
- 蛋白质翻译后修饰(糖基化)和肿瘤发生发展
- 肿瘤相关信号转导和蛋白质翻译异常
- 消化系统肿瘤癌前病变的发生机制和干预策略
Work Experience
- 2010.07—2012.09 - 复旦大学 - 基础医学流动站博士后
- 2012.09—2013.12 - 复旦大学 - 基础医学院讲师
- 2013.12—2018.12 - 复旦大学 - 基础医学院副研究员
- 2018.12—今 - 复旦大学 - 基础医学院教授
Academic Background & Achievements
- 2000.09—2005.06 法医学专业本科生: 复旦大学上海医学院
- 2005.09—2010.06 生物化学与分子生物学专业博士研究生: 复旦大学上海医学院
Publications
- Reticulon 3-mediated Chk2/p53 activation suppresses hepatocellular carcinogenesis and is blocked by hepatitis B virus., Song S, Shi Y, Wu W, Wu H, Chang L, Peng P, Zhang L, Fan J, Gu J, Ruan Y*, 2021
- O-GlcNAcylation of RACK1 promotes hepatocellular carcinogenesis., Duan F, Wu H, Jia D, Wu W, Ren S, Wang L, Song S, Guo X, Liu F*, Ruan Y*, Gu J, 2018
- C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits., Wang L#, Yin J#, Wang X#, Shao M, Duan F, Wu W, Peng P, Jin J, Tang Y, Ruan Y*, Sun Y*, Gu J*, 2016
- Loss of RACK1 Promotes Metastasis of Gastric Cancer by Inducing a miR-302c/IL8 Signaling Loop., Chen L#, Min L#, Wang X#, Zhao J, Chen H, Qin J, Chen W, Shen Z, Tang Z, Gan Q, Ruan Y*, Sun Y*, Qin X*, Gu J, 2015
- Ribosomal RACK1 promotes chemoresistance and growth in human hepatocellular carcinoma., Ruan Y, Sun L, Hao Y, Wang L, Xu J, Zhang W, Xie J, Guo L, Zhou L, Yun X, Zhu H, Shen A, Gu J*, 2012
Awards
- 2019: 仲英青年学者, 复旦大学
- 2015: 优秀博士后, 复旦大学