Professor | Xing Guo | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Xing Guo
Contact Information	guox@njmu.edu.cn
Language ability	English, Chinese
Province	Jiangsu

Upload Avatar (500 x 500)

Name

Xing Guo

Contact Information

guox@njmu.edu.cn

Language ability

English, Chinese

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2008.09-2011.07 PhD in Genetics: Peking Union Medical College National Excellent Young Scientist Fund recipient Jiangsu Province Distinguished Professor
Work Experience	2011.09-2016.10 - Case Western Reserve University - Postdoctoral Researcher 2016.10-2017.10 - Cleveland Clinic - Research Assistant 2017.10-present - Nanjing Medical University - Professor in the Department of Neurobiology
Awards	2013: Beijing Science and Technology Award

University/Lab Affiliation and Title

Nanjing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2008.09-2011.07 PhD in Genetics: Peking Union Medical College
National Excellent Young Scientist Fund recipient
Jiangsu Province Distinguished Professor

Work Experience

2011.09-2016.10 - Case Western Reserve University - Postdoctoral Researcher
2016.10-2017.10 - Cleveland Clinic - Research Assistant
2017.10-present - Nanjing Medical University - Professor in the Department of Neurobiology

Awards

2013: Beijing Science and Technology Award

Areas of Focus	Molecular mechanisms of neurodegenerative diseases and their intervention
Publications	Mitochondrial HSF1 triggers mitochondrial dysfunction and neurodegeneration in Huntington’s disease., Liu CY, Fu ZX, Wu SS, Wang XS, Zhang SR, Chu C, Hong Y, Wu WB, Chen SQ, Jiang YQ, Wu Y, Song YB, Liu Y, Guo X., 2022 Depressive patient-derived GABA interneurons reveal abnormal neural activity associated with HTR2C., Lu KQ, Hong Y, Tao MD, Shen LP, Zheng ZL, Fang KH, Yuan F, Xu M, Wang C, Zhu DY, Guo X, Liu Y., 2022 Dysfunction of vesicular storage in young-onset Parkinson’s patient-derived dopaminergic neurons and organoids revealed by single cell electrochemical cytometry., Zhu WY, Tao MD, Hong Y, Wu SS, Chu C, Zheng ZL, Han X, Zhu Q, Xu M, Ewing AG, Guo X, Liu Y., 2022 Human organoids in basic research and clinical applications., Tang XY, Wu SS, Wang D, Chu C, Hong Y, Tao MD, Hu H, Xu M, Guo X, Liu Y., 2022 DSCAM/PAK1 pathway suppression reverses neurogenesis deficits in iPSC-derived cerebral organoids from patients with Down syndrome., Tang XY, Xu L, Wang J, Hong Y, Wang Y, Zhu Q, Wang D, Zhang XY, Liu CY, Fang KH, Han X, Wang S, Wang X, Xu M, Bhattacharyya A, Guo X, Lin M, Liu Y., 2021 Abnormal mitochondria in Down syndrome iPSC-derived GABAergic interneurons and organoids., Xu L, Huo HQ, Lu KQ, Tang XY, Hong Y, Han X, Fu ZX, Fang KH, Xu M, Guo X, Liu Y., 2022 Mutant huntingtin inhibits the mitochondrial unfolded protein response by impairing ABCB10 mRNA stability., Fu ZX, Liu F, Liu CY, Jin BF, Jiang YQ, Tang ML, Qi X, Guo X., 2019 Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration., Guo X, Disatnik MH, Monbureau M, Shamloo M, Mochly-Rosen D, Qi X., 2013 VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease., Guo X, Sun X, Hu D, Wang YJ, Fujioka H, Vyas R, Chakrapani S, Joshi AU, Luo Y, Mochly-Rosen D, Qi X., 2016

Areas of Focus

Molecular mechanisms of neurodegenerative diseases and their intervention

Publications

Mitochondrial HSF1 triggers mitochondrial dysfunction and neurodegeneration in Huntington’s disease., Liu CY, Fu ZX, Wu SS, Wang XS, Zhang SR, Chu C, Hong Y, Wu WB, Chen SQ, Jiang YQ, Wu Y, Song YB, Liu Y, Guo X., 2022
Depressive patient-derived GABA interneurons reveal abnormal neural activity associated with HTR2C., Lu KQ, Hong Y, Tao MD, Shen LP, Zheng ZL, Fang KH, Yuan F, Xu M, Wang C, Zhu DY, Guo X, Liu Y., 2022
Dysfunction of vesicular storage in young-onset Parkinson’s patient-derived dopaminergic neurons and organoids revealed by single cell electrochemical cytometry., Zhu WY, Tao MD, Hong Y, Wu SS, Chu C, Zheng ZL, Han X, Zhu Q, Xu M, Ewing AG, Guo X, Liu Y., 2022
Human organoids in basic research and clinical applications., Tang XY, Wu SS, Wang D, Chu C, Hong Y, Tao MD, Hu H, Xu M, Guo X, Liu Y., 2022
DSCAM/PAK1 pathway suppression reverses neurogenesis deficits in iPSC-derived cerebral organoids from patients with Down syndrome., Tang XY, Xu L, Wang J, Hong Y, Wang Y, Zhu Q, Wang D, Zhang XY, Liu CY, Fang KH, Han X, Wang S, Wang X, Xu M, Bhattacharyya A, Guo X, Lin M, Liu Y., 2021
Abnormal mitochondria in Down syndrome iPSC-derived GABAergic interneurons and organoids., Xu L, Huo HQ, Lu KQ, Tang XY, Hong Y, Han X, Fu ZX, Fang KH, Xu M, Guo X, Liu Y., 2022
Mutant huntingtin inhibits the mitochondrial unfolded protein response by impairing ABCB10 mRNA stability., Fu ZX, Liu F, Liu CY, Jin BF, Jiang YQ, Tang ML, Qi X, Guo X., 2019
Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration., Guo X, Disatnik MH, Monbureau M, Shamloo M, Mochly-Rosen D, Qi X., 2013
VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease., Guo X, Sun X, Hu D, Wang YJ, Fujioka H, Vyas R, Chakrapani S, Joshi AU, Luo Y, Mochly-Rosen D, Qi X., 2016

Neurodegeneration Molecular Mechanisms Intervention Mitochondrial Quality Control Huntington'S Disease Neurobiology Genetics Stem Cells Neuroscience Clinical Applications

Bai Yun - Peking University

Genze Shao - Peking University

Mengcheng Luo - Wuhan University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us