Professor | Yuguang Shi | Asia Growth Partners

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Name

Yuguang Shi

Contact Information

syg@njmu.edu.cn

Language ability

Chinese, English

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1977-1982 Bachelor's in Animal Science: Northwest A&F University 1983-1986 Master's in Genetics: University of New England, Australia 1986-1991 PhD in Molecular Biology: Australian National University Cloned new genes related to familial diabetes and other conditions Published over 60 articles with a cumulative impact factor over 400
Work Experience	1991-1995 - University of California, San Francisco - Postdoctoral Researcher 1995-2006 - Eli Lilly and Company - Chief Scientist 2006-2014 - Pennsylvania State University - Tenured Professor 2014-present - Nanjing Medical University - Professor
Awards	1993: Postdoctoral Fellowship from the Juvenile Diabetes Research Foundation International 1995: Postdoctoral Fellowship from the National Institutes of Health and American Cancer Society 1997: Outstanding Team Award from Eli Lilly and Company 2004: Outstanding Research Award from Eli Lilly and Company 2012: Innovation Award from Pennsylvania State University 2016: Second Prize in Science and Technology from Jiangsu Province

University/Lab Affiliation and Title

Nanjing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

Work Experience

Awards

1993: Postdoctoral Fellowship from the Juvenile Diabetes Research Foundation International
1995: Postdoctoral Fellowship from the National Institutes of Health and American Cancer Society
1997: Outstanding Team Award from Eli Lilly and Company
2004: Outstanding Research Award from Eli Lilly and Company
2012: Innovation Award from Pennsylvania State University
2016: Second Prize in Science and Technology from Jiangsu Province

Areas of Focus	Molecular mechanisms of mitochondrial dysfunction and aging-related diseases
Publications	Cardiolipin remodeling by ALCAT1 links mitochondrial dysfunction to Parkinson's diseases., Song C, Zhang J, Qi S, Liu Z, Zhang X, Zheng Y, Andersen JP, Zhang W, Strong R, Martinez PA, Musi N, Nie J, Shi Y., 2019 Defective Phosphatidylglycerol Remodeling Causes Hepatopathy, Linking Mitochondrial Dysfunction to Hepatosteatosis., Zhang X, Zhang J, Sun H, Liu X, Zheng Y, Xu D, Wang J, Jia D, Han X, Liu F, Nie J, Shi Y., 2019 SAD-A Promotes Glucose-Stimulated Insulin Secretion Through Phosphorylation and Inhibition of GDIα in Male Islet β Cells., Jia Nie, Chao Sun, Chang Z, Nicolas Musi, Yuguang Shi., 2018 Regulation of autophagy by mitochondrial phospholipids in health and diseases., Paul Hsua, Yuguang Shi., 2017 ALCAT1 controls mitochondrial etiology of fatty liver diseases, linking defective mitophagy to steatosis., Li Wang, Xiaolei Liu, Jia Nie, Jun Zhang, Scot R. Kimball, Hai Zhang, Weiping J. Zhang, Leonard S. Jefferson, Zeneng Cheng, Qiuhe Ji, Yuguang Shi., 2015 Cardiolipin remodeling by TAZ/tafazzin is selectively required for the initiation of mitophagy., Hsu P, Liu X, Zhang J, Wang HG, Ye JM, Shi Y., 2015 Modulators of Acyl-CoA Lysocardiolipin Acyltransferase 1 (ALCAT1) and Uses Thereof, Yuguang Shi, 2015

Areas of Focus

Molecular mechanisms of mitochondrial dysfunction and aging-related diseases

Publications

Cardiolipin remodeling by ALCAT1 links mitochondrial dysfunction to Parkinson's diseases., Song C, Zhang J, Qi S, Liu Z, Zhang X, Zheng Y, Andersen JP, Zhang W, Strong R, Martinez PA, Musi N, Nie J*, Shi Y*., 2019
Defective Phosphatidylglycerol Remodeling Causes Hepatopathy, Linking Mitochondrial Dysfunction to Hepatosteatosis., Zhang X, Zhang J, Sun H, Liu X, Zheng Y, Xu D, Wang J, Jia D, Han X, Liu F, Nie J, Shi Y*., 2019
SAD-A Promotes Glucose-Stimulated Insulin Secretion Through Phosphorylation and Inhibition of GDIα in Male Islet β Cells., Jia Nie, Chao Sun, Chang Z, Nicolas Musi, Yuguang Shi*., 2018
Regulation of autophagy by mitochondrial phospholipids in health and diseases., Paul Hsua, Yuguang Shi*., 2017
ALCAT1 controls mitochondrial etiology of fatty liver diseases, linking defective mitophagy to steatosis., Li Wang, Xiaolei Liu, Jia Nie, Jun Zhang, Scot R. Kimball, Hai Zhang, Weiping J. Zhang, Leonard S. Jefferson, Zeneng Cheng, Qiuhe Ji*, Yuguang Shi*., 2015
Cardiolipin remodeling by TAZ/tafazzin is selectively required for the initiation of mitophagy., Hsu P, Liu X, Zhang J, Wang HG, Ye JM, Shi Y*., 2015
Modulators of Acyl-CoA Lysocardiolipin Acyltransferase 1 (ALCAT1) and Uses Thereof, Yuguang Shi, 2015

Mitochondria Aging Molecular Mechanisms Cardiolipin Metabolism Chronic Diseases Neurodegenerative Diseases Cancer Lipid Metabolism Heart Failure

Zhang Yu - Peking University

Zhengwei Xie - Peking University

Hongguang Xia - Zhejiang University

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