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Chongxiu Sun
Basic Medical Sciences
Nanjing Medical University
Jiangsu
Language: English, Chinese
Endothelial Dysfunction
Cardiovascular Diseases
Molecular Regulation
Endothelial Cells
Vascular Biology
Signal Transduction
Inflammation
Atherosclerosis
Vascular Homeostasis
Cell Signaling
Areas of Focus
- Role and molecular regulation of endothelial dysfunction in cardiovascular diseases
Work Experience
- 2015-present - Nanjing Medical University - Professor
- 2008-2014 - University of California - Research Assistant Professor
- 2006-2008 - Harvard Medical School - Postdoctoral Researcher
Academic Background & Achievements
- 2006 - PhD: Nanjing University
- 2015 - Jiangsu Distinguished Professor
Publications
- IRF-1 mediates the suppressive effects of mTOR inhibition on arterial endothelium., Peng K, Fan X, Li Q, Wang Y, Chen X, Xiao P, Passerini AG, Simon SI and Sun C*., 2020
- Downregulation of GATA6 in mTOR-inhibited human aortic endothelial cells: effects on TNFα-induced VCAM-1 expression and monocytic cell adhesion., Fan X, Chen X, Feng Q, Peng K, Wu Q, Passerini AG, Simon SI, Sun C*., 2019
- 11,12 Epoxyecosatrienoic acids mitigate endothelial dysfunction associated with estrogen loss and aging: Role of membrane depolarization., Sun C, Siimon SI, Foster GA, Radecke CE, Hwang HT, Zhang X, Hammock BD, Chiamvimonvat N, Knowlton AA., 2016
- Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter., Wang J#, Sun C#, Gerdes N, Liu C, Liao M, Liu J, Shi MA, He A, Zhou Y, Sukhova GK, Chen H, Cheng XW, Kuzuya M, Murohara T, Zhang J, Cheng X, Jiang M, Shull GE, Rogers S, Yang CL, Ke Q, Jelen S, Bindels R, Ellison DH, Jarolim P, Libby P, Shi GP., 2015
- ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice., Sun C, Rigor RR, Konia T, Wu MH and Yuan SY., 2013
- ADAM15 contributes to atherosclerosis by mediating endothelial barrier dysfunction via Src family kinase activity., Sun C, Wu MH, Lee ES, and Yuan S., 2012
- nmMLCK deficiency ameliorates atherosclerosis in ApoE-deficient mice via reduced endothelial barrier dysfunction and monocyte migration., Sun C, Wu MH, Yuan SY., 2011
- ADAM15 regulates endothelial permeability and neutrophil migration via Src/ERK1/2., Sun C, Wu MH, Guo M, Day ML, Lee ES, Yuan SY., 2010
- IRF-1 and miRNA126 Modulate VCAM-1 Expression in Response to a High Fat Meal., Sun C, Alkhoury K, Wang Y, Foster GA, Radecke CE, Tam K, Edwards CM, Facciotti MT, Armstrong EJ, Knowlton AA, Newman JW, Passerini AG, Simon SI., 2012
Awards
- 2015: Jiangsu Distinguished Professor
