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孙崇秀
Basic Medical Sciences
南京医科大学
江苏
Language: 英语, 中文
内皮功能失调
心血管疾病
分子调控
内皮细胞
血管生物学
信号转导
炎症
动脉粥样硬化
血管稳态
细胞信号
Areas of Focus
- 内皮功能失调在心血管疾病中的作用及分子调控
Work Experience
- 2015-至今 - 南京医科大学 - 教授
- 2008-2014 - 美国加州大学 - 科研助理教授
- 2006-2008 - 美国哈佛医学院 - 博士后研究学者
Academic Background & Achievements
- 2006 - 博士：南京大学
- 2015 - 江苏特聘教授
Publications
- IRF-1 mediates the suppressive effects of mTOR inhibition on arterial endothelium., Peng K, Fan X, Li Q, Wang Y, Chen X, Xiao P, Passerini AG, Simon SI and Sun C*., 2020
- Downregulation of GATA6 in mTOR-inhibited human aortic endothelial cells: effects on TNFα-induced VCAM-1 expression and monocytic cell adhesion., Fan X, Chen X, Feng Q, Peng K, Wu Q, Passerini AG, Simon SI, Sun C*., 2019
- 11,12 Epoxyecosatrienoic acids mitigate endothelial dysfunction associated with estrogen loss and aging: Role of membrane depolarization., Sun C, Siimon SI, Foster GA, Radecke CE, Hwang HT, Zhang X, Hammock BD, Chiamvimonvat N, Knowlton AA., 2016
- Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter., Wang J#, Sun C#, Gerdes N, Liu C, Liao M, Liu J, Shi MA, He A, Zhou Y, Sukhova GK, Chen H, Cheng XW, Kuzuya M, Murohara T, Zhang J, Cheng X, Jiang M, Shull GE, Rogers S, Yang CL, Ke Q, Jelen S, Bindels R, Ellison DH, Jarolim P, Libby P, Shi GP., 2015
- ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice., Sun C, Rigor RR, Konia T, Wu MH and Yuan SY., 2013
- ADAM15 contributes to atherosclerosis by mediating endothelial barrier dysfunction via Src family kinase activity., Sun C, Wu MH, Lee ES, and Yuan S., 2012
- nmMLCK deficiency ameliorates atherosclerosis in ApoE-deficient mice via reduced endothelial barrier dysfunction and monocyte migration., Sun C, Wu MH, Yuan SY., 2011
- ADAM15 regulates endothelial permeability and neutrophil migration via Src/ERK1/2., Sun C, Wu MH, Guo M, Day ML, Lee ES, Yuan SY., 2010
- IRF-1 and miRNA126 Modulate VCAM-1 Expression in Response to a High Fat Meal., Sun C, Alkhoury K, Wang Y, Foster GA, Radecke CE, Tam K, Edwards CM, Facciotti MT, Armstrong EJ, Knowlton AA, Newman JW, Passerini AG, Simon SI., 2012
Awards
- 2015: 江苏特聘教授
