Professor | Zhenyi Su | Asia Growth Partners

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Name	Zhenyi Su
Contact Information	zhenyisu@njmu.edu.cn
Language ability	English, Chinese
Province	Jiangsu

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Name

Zhenyi Su

Contact Information

zhenyisu@njmu.edu.cn

Language ability

English, Chinese

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2007-2012 PhD: Beijing Normal University, College of Life Sciences Research published in top journals like Nature Cancer, NCB, Cell Death and Differentiation, Genes & Development
Work Experience	2024-present - Nanjing Medical University, School of Basic Medical Sciences - Professor 2022-2024 - Columbia University, Institute for Cancer Genetics - Associate Research Scientist 2018-2022 - Columbia University, Institute for Cancer Genetics - Postdoctoral Researcher 2014-2016 - Harvard Medical School, Department of Cell Biology - Visiting Scholar 2012-2018 - Southeast University, School of Medicine - Lecturer

University/Lab Affiliation and Title

Nanjing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2007-2012 PhD: Beijing Normal University, College of Life Sciences
Research published in top journals like Nature Cancer, NCB, Cell Death and Differentiation, Genes & Development

Work Experience

2024-present - Nanjing Medical University, School of Basic Medical Sciences - Professor
2022-2024 - Columbia University, Institute for Cancer Genetics - Associate Research Scientist
2018-2022 - Columbia University, Institute for Cancer Genetics - Postdoctoral Researcher
2014-2016 - Harvard Medical School, Department of Cell Biology - Visiting Scholar
2012-2018 - Southeast University, School of Medicine - Lecturer

Areas of Focus	Cell Death Tumor Metabolism Tumor Metastasis
Publications	Specific regulation of BACH1 by the hot-spot mutant p53R175H reveals a distinct gain of function mechanism., Su, Z., Kon, N., Yi, J., Zhao, H., Zhang, W., Tang, Q., Li, H., …and Gu, W., 2023 ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner., Su, Z., Dziedzic, S. A., Hu, D., Barrett, V. J., Broekema, N., Li, W., ... & Yuan, J., 2019 ALOX5-mediated ferroptosis acts as a distinct cell death pathway upon oxidative stress in Huntington's disease., Song, S.#, Su, Z.#, Kon, N., Chu, B., Li, H., Jiang, X., ... & Gu, W., 2023 ABIN-1 is a key regulator in RIPK1-dependent apoptosis (RDA) and necroptosis, and ABIN-1 deficiency potentiates necroptosis-based cancer therapy in colorectal cancer., Cai, J., Hu, D., Sakya, J., Sun, T., Wang, D., Wang, L., Mao, X., and Su, Z., 2021 ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC., Dziedzic, S., Su, Z., Barrett, V., Najafov, A., Mookhtiar, A., Amin, P., ... and Yuan, J., 2018 Fluvastatin prevents lung adenocarcinoma bone metastasis by triggering autophagy., Yang, Z.#, Su, Z.#*, DeWitt, J.1, Xie, L., Chen, Y., Li, X., Li, D., Xia, J., Zhang, Y., and Yang, Y., 2017 Cancer therapy in the necroptosis era., Su Z., Yang Z., Xie L., DeWitt J., Chen Y., 2016 Apoptosis, autophagy, necroptosis, and cancer metastasis., Su, Z., Yang, Z., Xu, Y., Chen, Y., and Yu, Q., 2015 The synergistic interaction between the calcineurin B subunit and IFN-γ enhances macrophage antitumor activity., Su, Z., Yang, R., Zhang, W., Xu, L., Zhong, Y., Yin, Y., Cen, J., DeWitt, J., and Wei, Q., 2015

Areas of Focus

Cell Death
Tumor Metabolism
Tumor Metastasis

Publications

Specific regulation of BACH1 by the hot-spot mutant p53R175H reveals a distinct gain of function mechanism., Su, Z., Kon, N., Yi, J., Zhao, H., Zhang, W., Tang, Q., Li, H., …and Gu, W., 2023
ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner., Su, Z., Dziedzic, S. A., Hu, D., Barrett, V. J., Broekema, N., Li, W., ... & Yuan, J., 2019
ALOX5-mediated ferroptosis acts as a distinct cell death pathway upon oxidative stress in Huntington's disease., Song, S.#, Su, Z.#, Kon, N., Chu, B., Li, H., Jiang, X., ... & Gu, W., 2023
ABIN-1 is a key regulator in RIPK1-dependent apoptosis (RDA) and necroptosis, and ABIN-1 deficiency potentiates necroptosis-based cancer therapy in colorectal cancer., Cai, J., Hu, D., Sakya, J., Sun, T., Wang, D., Wang, L., Mao, X., and Su, Z.*, 2021
ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC., Dziedzic, S., Su, Z., Barrett, V., Najafov, A., Mookhtiar, A., Amin, P., ... and Yuan, J., 2018
Fluvastatin prevents lung adenocarcinoma bone metastasis by triggering autophagy., Yang, Z.#*, Su, Z.#*, DeWitt, J.1, Xie, L., Chen, Y., Li, X., Li, D., Xia, J., Zhang, Y., and Yang, Y., 2017
Cancer therapy in the necroptosis era., Su Z., Yang Z., Xie L., DeWitt J., Chen Y., 2016
Apoptosis, autophagy, necroptosis, and cancer metastasis., Su, Z., Yang, Z., Xu, Y., Chen, Y., and Yu, Q., 2015
The synergistic interaction between the calcineurin B subunit and IFN-γ enhances macrophage antitumor activity., Su, Z., Yang, R., Zhang, W., Xu, L., Zhong, Y., Yin, Y., Cen, J., DeWitt, J., and Wei, Q., 2015

Apoptosis Necroptosis Ferroptosis Cancer Metabolism Metastasis Cell Death Tumor Iron Therapy

Yan Weitao - Central South University

Yingying Xu - Fudan University

Jie Yan - Guangzhou Medical University

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