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苏振毅
Basic Medical Sciences
南京医科大学
江苏
Language: 英语, 中文
凋亡
坏死
铁死亡
癌症
代谢
转移
细胞死亡
肿瘤
铁
治疗
Areas of Focus
- 细胞死亡
- 肿瘤代谢
- 肿瘤转移
Work Experience
- 2024年至今 - 南京医科大学基础医学院 - 教授
- 2022-2024 - 美国哥伦比亚大学肿瘤遗传研究所 - 副研究员
- 2018-2022 - 美国哥伦比亚大学肿瘤遗传研究所 - 博士后
- 2014-2016 - 美国哈佛医学院细胞生物学系 - 访问学者
- 2012-2018 - 东南大学医学院 - 讲师
Academic Background & Achievements
- 2007-2012 博士: 北京师范大学生命科学学院
- 研究成果发表在《Nature Cancer》、《NCB》、《Cell Death and Differentiation》、《Genes & Development》等权威期刊
Publications
- Specific regulation of BACH1 by the hot-spot mutant p53R175H reveals a distinct gain of function mechanism., Su, Z., Kon, N., Yi, J., Zhao, H., Zhang, W., Tang, Q., Li, H., …and Gu, W., 2023
- ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner., Su, Z., Dziedzic, S. A., Hu, D., Barrett, V. J., Broekema, N., Li, W., ... & Yuan, J., 2019
- ALOX5-mediated ferroptosis acts as a distinct cell death pathway upon oxidative stress in Huntington's disease., Song, S.#, Su, Z.#, Kon, N., Chu, B., Li, H., Jiang, X., ... & Gu, W., 2023
- ABIN-1 is a key regulator in RIPK1-dependent apoptosis (RDA) and necroptosis, and ABIN-1 deficiency potentiates necroptosis-based cancer therapy in colorectal cancer., Cai, J., Hu, D., Sakya, J., Sun, T., Wang, D., Wang, L., Mao, X., and Su, Z.*, 2021
- ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC., Dziedzic, S., Su, Z., Barrett, V., Najafov, A., Mookhtiar, A., Amin, P., ... and Yuan, J., 2018
- Fluvastatin prevents lung adenocarcinoma bone metastasis by triggering autophagy., Yang, Z.#*, Su, Z.#*, DeWitt, J.1, Xie, L., Chen, Y., Li, X., Li, D., Xia, J., Zhang, Y., and Yang, Y., 2017
- Cancer therapy in the necroptosis era., Su Z., Yang Z., Xie L., DeWitt J., Chen Y., 2016
- Apoptosis, autophagy, necroptosis, and cancer metastasis., Su, Z., Yang, Z., Xu, Y., Chen, Y., and Yu, Q., 2015
- The synergistic interaction between the calcineurin B subunit and IFN-γ enhances macrophage antitumor activity., Su, Z., Yang, R., Zhang, W., Xu, L., Zhong, Y., Yin, Y., Cen, J., DeWitt, J., and Wei, Q., 2015
