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Changyan Ma
Basic Medical Sciences
Nanjing Medical University
Jiangsu
Language: Chinese, English
Epigenetics
Tumorigenesis
Metastasis
Osteoporosis
Osteoarthritis
Molecular Mechanisms
Cancer
Genetics
Bone
Disease
Areas of Focus
- Epigenetic mechanisms of tumorigenesis and metastasis
- Molecular mechanisms of osteoporosis and osteoarthritis
Work Experience
- 1995/8-2005/9 - Nanjing Medical University - Assistant Lecturer, Lecturer in Biology
- 2004/4-2006/12 - Nanjing Medical University - Postdoctoral Researcher at Jiangsu Key Laboratory of Human Functional Genomics
- 2005/10-2011/9 - Nanjing Medical University - Associate Professor in Cell Biology and Medical Genetics
- 2007/9-2007/12 - University of North Carolina at Charlotte - Visiting Scholar
- 2008/3-2009/9 - University of Alabama at Birmingham - Postdoctoral Researcher
- 2011/10-present - Nanjing Medical University - Professor in Medical Genetics
Academic Background & Achievements
- 1988/9-1992/7 Bachelor in Biology: Jiangsu Normal University
- 1992/9-1995/7 Master in Plant Physiology and Biochemistry: Nanjing Normal University
- 2000/9-2003/7 Doctorate in Zoology: Nanjing Normal University
- Published over 20 SCI papers in recent years
- Co-editor and contributor to 7 textbooks
Publications
- Establishment and characterization of an immortalized human chondrocyte cell line, Yang J, Tang Y, Chen W, Zhang M, Hong F, Yang D, Bao Q, Yang Y, Jin Y, Li L, Ma C, 2020
- Icariin promotes osteogenic differentiation by suppressing Notch signaling, Xu Y, Li L, Tang Y, Yang J, Jin Y, Ma C, 2019
- αB-crystallin (CRYAB) regulates the proliferation, apoptosis, synthesis and degradation of extracellular matrix of chondrocytes in osteoarthritis, Bao Q, Yang D, Hong F, Yang J, Li L, Jin Y, Ma C, 2019
- Upregulated osterix promotes invasion and bone metastasis and predicts for a poor prognosis in breast cancer, Yao B, Wang J, Qu S, Liu Y, Jin Y, Lu J, Bao Q, Li L, Yuan H, Ma C, 2019
- Osterix promotes the migration and angiogenesis of breast cancer by upregulation of S100A4 expression, Qu S, Wu J, Bao Q, Yao B, Duan R, Chen X, Li L, Yuan H, Jin Y, Ma C, 2019
- Osterix Decreases the Chemosensitivity of Breast Cancer Cells by Upregulating GALNT14, Wu J, Chen X, Bao Q, Duan R, Jin Y, Shui Y, Yao B, Lu X, Wang Y, Cui H, Li L, Yuan H, Ma C, 2017
- miR-130b-3p inhibits cell invasion and migration by targeting the Notch ligand Delta-like 1 in breast carcinoma, Shui Y, Yu X, Duan R, Bao Q, Wu J, Yuan H, Ma C, 2017
- Osterix acetylation at K307 and K312 enhances its transcriptional activity and is required for osteoblast differentiation, Lu J, Qu S, Yao B, Xu Y, Jin Y, Shi K, Shui Y, Pan S, Chen L, Ma C, 2016
- Phosphorylation of Serine422 increases the stability and transactivation activities of human Osterix, Xu Y, Yao B, Shi K, Lu J, Jin Y, Qi B, Li H, Pan S, Chen L, Ma C, 2015
Awards
- 2006: Jiangsu Province 'Qinglan Project' Outstanding Young Backbone Teacher
- 2012: Nanjing Medical University Sixth 'Yangtze River Teaching Award'
