Professor | Bin Xue | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Bin Xue
Contact Information	xuebin@njmu.edu.cn
Language ability	Chinese, English
Province	Jiangsu

Upload Avatar (500 x 500)

Name

Bin Xue

Contact Information

xuebin@njmu.edu.cn

Language ability

Chinese, English

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1997-09 to 2001-06 Bachelor: Nanjing Normal University, Department of Cell Biology 2001-09 to 2006-06 Doctorate: Nanjing Normal University, Department of Cell Biology
Work Experience	2006-09 to 2012-12 - Nanjing University Medical School - Lecturer/Associate Professor 2013-01 to 2014-03 - Harvard Medical School - Department of Cell Biology 2014-04 to 2019-04 - Nanjing University Medical School - Associate Professor, Doctoral Supervisor, Director of Translational Medicine Center Laboratory 2019-04 to 2024-08 - Nanjing Medical University Affiliated Yifu Hospital - Director of Translational Medicine Research Center 2024-08 to present - Nanjing Medical University Affiliated Children's Hospital - Director of Translational Medicine Research Center, Part-time Professor at Basic Medical College
Awards	2022: Third Prize of Huaxia Medical Science and Technology Award 2024: Special Prize of the Fourth Jiangsu Province University Teachers' Teaching Innovation Competition Jiangsu Province University Micro-lecture Teaching Competition Second Prize

University/Lab Affiliation and Title

Nanjing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1997-09 to 2001-06 Bachelor: Nanjing Normal University, Department of Cell Biology
2001-09 to 2006-06 Doctorate: Nanjing Normal University, Department of Cell Biology

Work Experience

2006-09 to 2012-12 - Nanjing University Medical School - Lecturer/Associate Professor
2013-01 to 2014-03 - Harvard Medical School - Department of Cell Biology
2014-04 to 2019-04 - Nanjing University Medical School - Associate Professor, Doctoral Supervisor, Director of Translational Medicine Center Laboratory
2019-04 to 2024-08 - Nanjing Medical University Affiliated Yifu Hospital - Director of Translational Medicine Research Center
2024-08 to present - Nanjing Medical University Affiliated Children's Hospital - Director of Translational Medicine Research Center, Part-time Professor at Basic Medical College

Awards

2022: Third Prize of Huaxia Medical Science and Technology Award
2024: Special Prize of the Fourth Jiangsu Province University Teachers' Teaching Innovation Competition
Jiangsu Province University Micro-lecture Teaching Competition Second Prize

Areas of Focus	Mechanisms of metabolic diseases induced by liver/bone axis metabolic homeostasis imbalance Liver multi-tissue spatiotemporal dialogue and disease occurrence Mechanisms of metabolic diseases induced by environmental exposure Screening of new natural drugs for metabolic diseases
Publications	Defects in a liver-bone axis contribute to hepatic osteodystrophy disease progression., Ke Lu, Tian-Shu Shi, Si-Yu Shen, Yong Shi, Hong-Liang Gao, Jing Wu, Xiang Lu, Xiang Gao, Huang-xian Ju, Wei Wang, Yi Cao, Di Chen, Chao-Jun Li, Bin Xue, Qing Jiang, 2022 Total parenteral nutrition impairs glucose metabolism by modifying the gut microbiome., Wang P, Sun H, Maitiabula G, Zhang L, Yang J, Zhang Y, Gao X, Li J, Xue B, Li CJ, Wang X, 2023 PP2Acα positively regulates the termination of liver regeneration in mice through the AKT/GSK3β/Cyclin D1 pathway., Lai SS, Zhao DD, Cao P, Lu K, Luo OY, Chen WB, Liu J, Jiang EZ, Yu ZH, Lee G, Li J, Yu DC, Xu XJ, Zhu MS, Gao X, Li CJ, Xue B, 2016 The rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice., Wu J, Bu D, Wang H, Shen D, Chong D, Zhang T, Tao W, Zhao M, Zhao Y, Fang L, Li P, Xue B, Li CJ, 2023 Liver governs adipose remodelling via extracellular vesicles in response to lipid overload., Yue Zhao, Mengfei Zhao, Shan Jiang, Jing Wu, Jia Liu, Xianwen Yuan, Di Shen, Jingzi Zhang, Nan Zhou, Jian He, Lei Fang, Xitai Sun, Bin Xue, Chaojun Li, 2020 Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice., Yu X, Shen N, Zhang ML, Pan FY, Wang C, Jia WP, Liu C, Gao Q, Gao X, Xue B, Li CJ, 2011 Manipulating PP2Acα-ASK-JNK signaling to favor apoptotic over necroptotic hepatocyte fate reduces the extent of necrosis and fibrosis upon acute liver injury., Ke Lu, Si-Yu Shen, Ou-Yang Luo, Yue Lu, Tian-Shu Shi, Jing Wu, Qi Cheng, Hua-Jian Teng, Di Chen, Xiang Lu, Chao-Jun Li, Qing Jiang, Lei Fang, Bin Xue, 2022 Liver PP2A-Cα Protects From Parenteral Nutrition-associated Hepatic Steatosis., Maitiabula G, Tian F, Wang P, Zhang L, Gao X, Wan S, Sun H, Yang J, Zhang Y, Gao T, Xue B, Li C, Li J, Wang X, 2022 Geranylgeranyl diphosphate synthase (GGPPS) regulates non-alcoholic fatty liver disease (NAFLD)-fibrosis progression by determining hepatic glucose/fatty acid preference under high-fat diet conditions., Jia Liu, Shan Jiang, Yue Zhao, Qian Sun, Jingzi Zhang, Di Shen, Jing Wu, Ning Shen, Xiao Fu, Xitai Sun, Decai Yu, Jun Chen, Jian He, Tingting Shi, Yitao Ding, Lei Fang, Bin Xue, Chaojun Li, 2018 GGPPS-mediated Rab27A geranylgeranylation regulates β cell dysfunction during type 2 diabetes development by affecting insulin granule docked pool formation., Jiang S, Shen D, Jia WJ, Han X, Shen N, Tao W, Gao X, Xue B, Li CJ, 2016

Areas of Focus

Mechanisms of metabolic diseases induced by liver/bone axis metabolic homeostasis imbalance
Liver multi-tissue spatiotemporal dialogue and disease occurrence
Mechanisms of metabolic diseases induced by environmental exposure
Screening of new natural drugs for metabolic diseases

Publications

Defects in a liver-bone axis contribute to hepatic osteodystrophy disease progression., Ke Lu, Tian-Shu Shi, Si-Yu Shen, Yong Shi, Hong-Liang Gao, Jing Wu, Xiang Lu, Xiang Gao, Huang-xian Ju, Wei Wang, Yi Cao, Di Chen, Chao-Jun Li, Bin Xue, Qing Jiang, 2022
Total parenteral nutrition impairs glucose metabolism by modifying the gut microbiome., Wang P, Sun H, Maitiabula G, Zhang L, Yang J, Zhang Y, Gao X, Li J, Xue B, Li CJ, Wang X, 2023
PP2Acα positively regulates the termination of liver regeneration in mice through the AKT/GSK3β/Cyclin D1 pathway., Lai SS, Zhao DD, Cao P, Lu K, Luo OY, Chen WB, Liu J, Jiang EZ, Yu ZH, Lee G, Li J, Yu DC, Xu XJ, Zhu MS, Gao X, Li CJ, Xue B, 2016
The rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice., Wu J, Bu D, Wang H, Shen D, Chong D, Zhang T, Tao W, Zhao M, Zhao Y, Fang L, Li P, Xue B, Li CJ, 2023
Liver governs adipose remodelling via extracellular vesicles in response to lipid overload., Yue Zhao, Mengfei Zhao, Shan Jiang, Jing Wu, Jia Liu, Xianwen Yuan, Di Shen, Jingzi Zhang, Nan Zhou, Jian He, Lei Fang, Xitai Sun, Bin Xue, Chaojun Li, 2020
Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice., Yu X, Shen N, Zhang ML, Pan FY, Wang C, Jia WP, Liu C, Gao Q, Gao X, Xue B, Li CJ, 2011
Manipulating PP2Acα-ASK-JNK signaling to favor apoptotic over necroptotic hepatocyte fate reduces the extent of necrosis and fibrosis upon acute liver injury., Ke Lu, Si-Yu Shen, Ou-Yang Luo, Yue Lu, Tian-Shu Shi, Jing Wu, Qi Cheng, Hua-Jian Teng, Di Chen, Xiang Lu, Chao-Jun Li, Qing Jiang, Lei Fang, Bin Xue, 2022
Liver PP2A-Cα Protects From Parenteral Nutrition-associated Hepatic Steatosis., Maitiabula G, Tian F, Wang P, Zhang L, Gao X, Wan S, Sun H, Yang J, Zhang Y, Gao T, Xue B, Li C, Li J, Wang X, 2022
Geranylgeranyl diphosphate synthase (GGPPS) regulates non-alcoholic fatty liver disease (NAFLD)-fibrosis progression by determining hepatic glucose/fatty acid preference under high-fat diet conditions., Jia Liu, Shan Jiang, Yue Zhao, Qian Sun, Jingzi Zhang, Di Shen, Jing Wu, Ning Shen, Xiao Fu, Xitai Sun, Decai Yu, Jun Chen, Jian He, Tingting Shi, Yitao Ding, Lei Fang, Bin Xue, Chaojun Li, 2018
GGPPS-mediated Rab27A geranylgeranylation regulates β cell dysfunction during type 2 diabetes development by affecting insulin granule docked pool formation., Jiang S, Shen D, Jia WJ, Han X, Shen N, Tao W, Gao X, Xue B, Li CJ, 2016

Liver Bone Metabolism Homeostasis Disease Mechanism Imbalance Natural Drugs Screening Environmental Exposure

Dengshun Miao - Nanjing Medical University

Changyan Ma - Nanjing Medical University

Xiaochun Bai - Southern Medical University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us