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Xiao Zhang
Basic Medical Sciences
Nanjing Medical University
Jiangsu
Language: English, Chinese
Antibody
Drug Development
Human
Immunotherapy
Tumor
Pathology
Mechanism
Cancer
Therapy
Research
Areas of Focus
- Development of fully human antibody drugs
- Tumor pathology mechanisms and tumor immunotherapy
Work Experience
- 2011/09 - Present: Lecturer/Associate Professor at Nanjing Medical University, School of Basic Medical Sciences
- 2015/04 - 2016/04: Visiting Scholar at Harvard University, Massachusetts General Hospital
Academic Background & Achievements
- 2011/09 - Present: Lecturer/Associate Professor at Nanjing Medical University, School of Basic Medical Sciences
- 2015/04 - 2016/04: Visiting Scholar at Harvard University, Massachusetts General Hospital
- 2008/09 - 2011/07: PhD at Nanjing Medical University, School of Basic Medical Sciences
- 2004/09 - 2007/07: Master's at Nanjing Normal University, School of Life Sciences
- 2000/09 - 2004/07: Bachelor's at Shanxi Normal University, School of Life Sciences
- Hosted 2 National Natural Science Foundation projects, 1 Jiangsu Science and Technology Department project, 1 Jiangsu Education Department project
- Received 5 national invention patents
Publications
- Induction of autophagy-dependent apoptosis in cancer cells through activation of ER stress: an uncovered anti-cancer mechanism by anti-alcoholism drug disulfiram., Zhang X, Hu P, Ding SY, Sun T, Liu L, Han S, DeLeo AB, Sadagopan A, Guo W, Wang X., 2019
- A novel chemoradiation targeting stem and nonstem pancreatic cancer cells by repurposing disulfiram., Juan Cong, Yangyang Wang, Xiao Zhang, Nan Zhang, Ling Liu, Klara Soukup, Theodoros Michelakos, Theodore Hong, Albert DeLeo, Lei Cai, Francesco Sabbatino, Soldano Ferrone, Hang Lee, Vera Levina, Bryan Fuchs, Kenneth Tanabe, Keith Lillemoe, Cristina Ferrone, Xinhui Wang., 2017
- Transcription factor p8 regulates autophagy in response to disulfiram via PI3K/mTOR/p70S6K signaling pathway in pancreatic cancer cells., Yao Z, Li X, Gao J, Wang Y, Xiao L, Chang X, Liu F, Feng Z, Zhang X., 2022
- Human 4F5 single-chain Fv antibody recognizing a conserved HA1 epitope has broad neutralizing potency against H5N1 influenza A viruses of different clades., Xiao Zhang, Xian Qi, Qianqian Zhang, Xiaoyan Zeng, Zhenqing Feng, Yongjun Jiao et al., 2013
- The protective effect of a combination of human intracellular and extracellular antibodies against the highly pathogenic avian influenza H5N1 virus., Qiu Jin, Zhangyu Yao, Fangzhou Liu, Yaxuan Di, Jun Gao, Xiao Zhang., 2022
Awards
- 2021: First Prize, 17th Jiangsu 'Challenge Cup' University Student Extracurricular Academic Science and Technology Works Competition, as a guiding teacher
