1997.09–2000.06 PhD in Zoology: Sun Yat-sen University
1994.09–1997.06 Master's in Aquatic Biology: Huazhong Agricultural University
1990.09–1994.06 Bachelor's in Aquatic Biology: Huazhong Agricultural University
2009.12–Present - Southern Medical University, Guangzhou - Researcher
2008.01–2009.11 - Southern Medical University, Guangzhou - Associate Researcher
2006.07–2007.12 - Southern Medical University, Guangzhou - Associate Researcher
2004.04–2005.05 - Stowers Institute for Medical Research, USA - Postdoctoral Researcher
2001.11–2003.12 - Sun Yat-sen University, Guangzhou - Lecturer, Postdoctoral Researcher
2001.01–2001.10 - Sun Yat-sen Medical University, Guangzhou - Lecturer, Postdoctoral Researcher
2000.07–2000.12 - Sun Yat-sen Medical University, Guangzhou - Lecturer, Postdoctoral Researcher
Research
Nasopharyngeal carcinoma pathogenesis Liver regeneration and liver-related diseases pathogenesis RNA methylation modifications and autophagy Glucose and lipid metabolism Genetically engineered pig models for human diseases
Autophagy induction promoted by m6A reader YTHDF3 through translation upregulation of FOXO3 mRNA., Hao W*, Dian M*, Zhou Y, Zhong Q, Pang W, Li Z, Zhao Y, Ma J, Lin X, Luo R, Li Y, Jia J, Shen H, Huang S, Dai G, Wang J#, Sun Y#, Xiao D#., 2022
Epitranscriptomic turbo for autophagy boost: m6A reader YTHDF3., Hao W*, Dian M*, Wang J#, Sun Y#, Xiao D#., 2022
Brown Adipose Tissue: A Potential Site for Islet Transplantation., Xu K*, Xie R*, Lin X*, Jia J, Zeng N, Li W, Xiao D#, Du T#., 2020
Optimization strategy for generating gene-edited Tibet Minipigs by synchronized oestrus and cytoplasmic microinjection., Chen BZ, Gu P, Jia JS, Liu W, Liu YM, Liu W, Xu T, Lin XL, Lin TY, Liu Y, Chen HW, Xu MC, Yuan J, Zhang JN, Zhang Y#, Xiao D#, Gu WW#., 2019
Silencing of microRNA-708 promotes cell growth and epithelial-to-mesenchymal transition by activating the SPHK2/AKT/b-catenin pathway in glioma., Chen Y, Deng X, Chen W, Shi P, Lian M, Wang H, Wang K, Qian D, Xiao D#, Long H#., 2019
miR-26a promotes hepatocellular carcinoma invasion and metastasis by inhibiting PTEN and inhibits cell growth by repressing EZH2., Zhao WT, Lin XL, Liu Y, Han LX, Li J, Lin TY, Shi JW, Wang SC, Lian M, Chen HW, Sun Y, Xu K, Jia JS#, Luo RC#, Xiao D#., 2019
Direct conversion of pig fibroblasts to chondrocyte-like cells by c-Myc., Shi JW, Zhang TT, Liu W, Yang J, Lin XL, Jia JS, Shen HF, Wang SC, Li J, Zhao WT, Gu WW#, Sun Y#, Xiao D#., 2019
TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway., Bie YN, Gu P, Chen YT, Zhou XX, Tian YG, Yang Q, Li HY, Lin X, Guan YH, Lin TY, Lu X, Shen HF, Fang TX, Liu YM, Xiao D#, Gu WW#., 2019
miR-155 accelerates proliferation of mouse hepatocytes during liver regeneration by directly targeting SOCS1., Lin X, Chen L, Li H, Liu Y, Guan Y, Li X, Jia Z, Lin X, Jia J, Sun Y, Xiao D#., 2018
miR-155 enhances insulin sensitivity by coordinated regulation of multiple genes in mice., Lin XL, Qin YJ, Jia JS, Lin TY, Lin X, Chen L, Zeng H, Han YJ, Wu LH, Huang S, Wang M, Huang SH, Xie RY, Liang LQ, Liu Y, Liu RY, Zhang TT, Li J, Wang SC, Sun PH, Huang WH, Yao KT#, Xu K#, Du T#, Xiao D#., 2016
Recognition and killing of cancer stem-like cell population in hepatocellular carcinoma cells by cytokine-induced killer cells via NKG2d-ligands recognition., Rong XX, Wei F, Lin XL, Qin YJ, Chen L, Wang HY, Shen HF, Jia LT, Xie RY, Lin TY, Hao WC, Yang J, Yang S, Chen YS, Huang WH, Li AM, Sun Y#, Luo RC#, Xiao D#., 2016
MicroRNA-19 triggers epithelial-mesenchymal transition of lung cancer cells accompanied by growth inhibition., Li J, Yang S, Yan W, Yang J, Qin YJ, Lin XL, Xie RY, Wang SC, Jin W, Gao F, Shi JW, Zhao WT, Jia JS, Shen HF, Ke JR, Liu B, Zhao YQ, Huang WH, Yao KT#, Li DJ#, Xiao D#., 2015
Overexpression of miR-155 in the liver of transgenic mice alters the expression profiling of hepatic genes associated with lipid metabolism., Lin X, Jia J, Du T, Li W, Wang X, Wei J, Lin X, Zeng H, Yao L, Chen X, Zhuang J, Weng J, Liu Y, Lin J, Wu Q, Wang W, Yao K#, Xu K#, Xiao D#., 2015
Hes1 is involved in the self-renewal and tumourigenicity of stem-like cancer cells in colon cancer., Gao F#, Zhang Y, Wang S, Liu Y, Zheng L, Yang J, Huang W, Ye Y, Luo W#, Xiao D#., 2014
The enforced expression of c-Myc in pig fibroblasts triggers mesenchymal-epithelial transition (MET) via F-actin reorganization and RhoA/Rock pathway inactivation., Shi JW, Liu W, Zhang TT, Wang SC, Lin XL, Li J, Jia JS, Sheng HF, Yao ZF, Zhao WT, Zhao ZL, Xie RY, Yang S, Gao F, Fan QR, Zhang MY, Yue M, Yuan J#, Gu WW#, Yao KT#, Xiao D#., 2013
Tetracycline-inducible expression systems: new strategies and practices in the transgenic mouse modeling., Sun Y, Chen XG#, Xiao D#., 2007
Tetracycline-controlled transcriptional regulation systems: countermeasures to eliminate basal transgene leak of Tet-based systems., Xiao D#, Sun Y, Gu WW, Chen XG#., 2007
Temporal control of Cre recombinase-mediated in vitro DNA recombination by the Tet-on system., Guo ZM, Xu K, Yue Y, Huang B, Tang H, Deng XY, Zhong LQ, Hong X, Chen XG#, Xiao D#., 2005
Cysteamine—a somatostatin-inhibiting agent—induced growth hormone secretion and growth acceleration in juvenile grass carp (Ctenopharyngodon idellus)., Xiao D#, Lin HR., 2003
Effects of cysteamine—a somatostatin-inhibiting agent on serum growth hormone (GH) levels and growth in juvenile grass carp (Ctenopharyngodon idellus)., Xiao D#, Lin HR., 2003
Regulation of growth hormone release in common carp pituitary cells by pituitary adenylate cyclase-activating polypeptide: Signal transduction involves cAMP- and calcium-dependent mechanisms., Xiao D#, Chu MM, Lee EK, Lin HR, Wong AOL., 2002
Lack of growth hormone-releasing peptide-6 (GHRP-6) action on in vivo and in vitro growth hormone secretion in sexually immatured grass carp (Ctenopharyngodon idellus)., Xiao D#, Wong AOL, Lin HR., 2002
Keywords
Cancer PathogenesisNasopharyngeal CarcinomaLiver RegenerationLiver DiseasesRna MethylationAutophagyGlucose MetabolismLipid MetabolismGenetic EngineeringAnimal Models