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Xiao Dong
xiaodong@smu.edu.cn
English, Chinese
Guangdong
Southern Medical University
Basic Medical Sciences
  • 1997.09–2000.06 PhD in Zoology: Sun Yat-sen University
  • 1994.09–1997.06 Master's in Aquatic Biology: Huazhong Agricultural University
  • 1990.09–1994.06 Bachelor's in Aquatic Biology: Huazhong Agricultural University
  • 2009.12–Present - Southern Medical University, Guangzhou - Researcher
  • 2008.01–2009.11 - Southern Medical University, Guangzhou - Associate Researcher
  • 2006.07–2007.12 - Southern Medical University, Guangzhou - Associate Researcher
  • 2004.04–2005.05 - Stowers Institute for Medical Research, USA - Postdoctoral Researcher
  • 2001.11–2003.12 - Sun Yat-sen University, Guangzhou - Lecturer, Postdoctoral Researcher
  • 2001.01–2001.10 - Sun Yat-sen Medical University, Guangzhou - Lecturer, Postdoctoral Researcher
  • 2000.07–2000.12 - Sun Yat-sen Medical University, Guangzhou - Lecturer, Postdoctoral Researcher
Nasopharyngeal carcinoma pathogenesis
Liver regeneration and liver-related diseases pathogenesis
RNA methylation modifications and autophagy
Glucose and lipid metabolism
Genetically engineered pig models for human diseases
  • Autophagy induction promoted by m6A reader YTHDF3 through translation upregulation of FOXO3 mRNA., Hao W*, Dian M*, Zhou Y, Zhong Q, Pang W, Li Z, Zhao Y, Ma J, Lin X, Luo R, Li Y, Jia J, Shen H, Huang S, Dai G, Wang J#, Sun Y#, Xiao D#., 2022
  • Epitranscriptomic turbo for autophagy boost: m6A reader YTHDF3., Hao W*, Dian M*, Wang J#, Sun Y#, Xiao D#., 2022
  • Brown Adipose Tissue: A Potential Site for Islet Transplantation., Xu K*, Xie R*, Lin X*, Jia J, Zeng N, Li W, Xiao D#, Du T#., 2020
  • Optimization strategy for generating gene-edited Tibet Minipigs by synchronized oestrus and cytoplasmic microinjection., Chen BZ, Gu P, Jia JS, Liu W, Liu YM, Liu W, Xu T, Lin XL, Lin TY, Liu Y, Chen HW, Xu MC, Yuan J, Zhang JN, Zhang Y#, Xiao D#, Gu WW#., 2019
  • Silencing of microRNA-708 promotes cell growth and epithelial-to-mesenchymal transition by activating the SPHK2/AKT/b-catenin pathway in glioma., Chen Y, Deng X, Chen W, Shi P, Lian M, Wang H, Wang K, Qian D, Xiao D#, Long H#., 2019
  • miR-26a promotes hepatocellular carcinoma invasion and metastasis by inhibiting PTEN and inhibits cell growth by repressing EZH2., Zhao WT, Lin XL, Liu Y, Han LX, Li J, Lin TY, Shi JW, Wang SC, Lian M, Chen HW, Sun Y, Xu K, Jia JS#, Luo RC#, Xiao D#., 2019
  • Direct conversion of pig fibroblasts to chondrocyte-like cells by c-Myc., Shi JW, Zhang TT, Liu W, Yang J, Lin XL, Jia JS, Shen HF, Wang SC, Li J, Zhao WT, Gu WW#, Sun Y#, Xiao D#., 2019
  • TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway., Bie YN, Gu P, Chen YT, Zhou XX, Tian YG, Yang Q, Li HY, Lin X, Guan YH, Lin TY, Lu X, Shen HF, Fang TX, Liu YM, Xiao D#, Gu WW#., 2019
  • miR-155 accelerates proliferation of mouse hepatocytes during liver regeneration by directly targeting SOCS1., Lin X, Chen L, Li H, Liu Y, Guan Y, Li X, Jia Z, Lin X, Jia J, Sun Y, Xiao D#., 2018
  • miR-155 enhances insulin sensitivity by coordinated regulation of multiple genes in mice., Lin XL, Qin YJ, Jia JS, Lin TY, Lin X, Chen L, Zeng H, Han YJ, Wu LH, Huang S, Wang M, Huang SH, Xie RY, Liang LQ, Liu Y, Liu RY, Zhang TT, Li J, Wang SC, Sun PH, Huang WH, Yao KT#, Xu K#, Du T#, Xiao D#., 2016
  • Recognition and killing of cancer stem-like cell population in hepatocellular carcinoma cells by cytokine-induced killer cells via NKG2d-ligands recognition., Rong XX, Wei F, Lin XL, Qin YJ, Chen L, Wang HY, Shen HF, Jia LT, Xie RY, Lin TY, Hao WC, Yang J, Yang S, Chen YS, Huang WH, Li AM, Sun Y#, Luo RC#, Xiao D#., 2016
  • MicroRNA-19 triggers epithelial-mesenchymal transition of lung cancer cells accompanied by growth inhibition., Li J, Yang S, Yan W, Yang J, Qin YJ, Lin XL, Xie RY, Wang SC, Jin W, Gao F, Shi JW, Zhao WT, Jia JS, Shen HF, Ke JR, Liu B, Zhao YQ, Huang WH, Yao KT#, Li DJ#, Xiao D#., 2015
  • Overexpression of miR-155 in the liver of transgenic mice alters the expression profiling of hepatic genes associated with lipid metabolism., Lin X, Jia J, Du T, Li W, Wang X, Wei J, Lin X, Zeng H, Yao L, Chen X, Zhuang J, Weng J, Liu Y, Lin J, Wu Q, Wang W, Yao K#, Xu K#, Xiao D#., 2015
  • Hes1 is involved in the self-renewal and tumourigenicity of stem-like cancer cells in colon cancer., Gao F#, Zhang Y, Wang S, Liu Y, Zheng L, Yang J, Huang W, Ye Y, Luo W#, Xiao D#., 2014
  • The enforced expression of c-Myc in pig fibroblasts triggers mesenchymal-epithelial transition (MET) via F-actin reorganization and RhoA/Rock pathway inactivation., Shi JW, Liu W, Zhang TT, Wang SC, Lin XL, Li J, Jia JS, Sheng HF, Yao ZF, Zhao WT, Zhao ZL, Xie RY, Yang S, Gao F, Fan QR, Zhang MY, Yue M, Yuan J#, Gu WW#, Yao KT#, Xiao D#., 2013
  • Tetracycline-inducible expression systems: new strategies and practices in the transgenic mouse modeling., Sun Y, Chen XG#, Xiao D#., 2007
  • Tetracycline-controlled transcriptional regulation systems: countermeasures to eliminate basal transgene leak of Tet-based systems., Xiao D#, Sun Y, Gu WW, Chen XG#., 2007
  • Temporal control of Cre recombinase-mediated in vitro DNA recombination by the Tet-on system., Guo ZM, Xu K, Yue Y, Huang B, Tang H, Deng XY, Zhong LQ, Hong X, Chen XG#, Xiao D#., 2005
  • Cysteamine—a somatostatin-inhibiting agent—induced growth hormone secretion and growth acceleration in juvenile grass carp (Ctenopharyngodon idellus)., Xiao D#, Lin HR., 2003
  • Effects of cysteamine—a somatostatin-inhibiting agent on serum growth hormone (GH) levels and growth in juvenile grass carp (Ctenopharyngodon idellus)., Xiao D#, Lin HR., 2003
  • Regulation of growth hormone release in common carp pituitary cells by pituitary adenylate cyclase-activating polypeptide: Signal transduction involves cAMP- and calcium-dependent mechanisms., Xiao D#, Chu MM, Lee EK, Lin HR, Wong AOL., 2002
  • Lack of growth hormone-releasing peptide-6 (GHRP-6) action on in vivo and in vitro growth hormone secretion in sexually immatured grass carp (Ctenopharyngodon idellus)., Xiao D#, Wong AOL, Lin HR., 2002
Cancer Pathogenesis Nasopharyngeal Carcinoma Liver Regeneration Liver Diseases Rna Methylation Autophagy Glucose Metabolism Lipid Metabolism Genetic Engineering Animal Models

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