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Chunhua Yuan
Basic Medical Sciences
Southern Medical University
Guangdong
Language: Chinese, English
Natural Drugs
Nerve System Diseases
Ion Channels
Drug Screening
Mechanism Of Action
Nervous System
Pharmacology
Peptides
Small Molecules
Structure-Function Relationships
Areas of Focus
- Drug screening and mechanism of action targeting nervous system diseases
Work Experience
- 2007-present - Southern Medical University - Research in neurobiology, focusing on pharmacology and structure-function relationships of peptides and small molecules
Academic Background & Achievements
- 1999 - Bachelor of Science: Hunan Normal University
- 2003 - Master of Science: Hunan Normal University
- 2007 - Doctor of Science: Hunan Normal University
Publications
- Removal of hERG potassium channel affinity through introduction of an oxygen atom: Molecular insights from structure-activity relationships of strychnine and its analogs., Yuan C, Luo Z, Zhou Y, Lei S, Xu C, Peng C, Li S, Li X, Zhu X, Gao T., 2018
- Jingzhaotoxin-35, a novel gating-modifier toxin targeting both Nav1.5 and Kv2.1 channels., Wei P, Xu C, Wu Q, Huang L, Liang S, Yuan C., 2014
- JZTX-XIII, a Kv channel gating-modifier toxin from Chinese tarantula Chilobrachys jingzhao., Yuan C, Liu Z, Hu W, Gao T, Liang S., 2012
- Inhibition of human Nav1.5 sodium channels by strychnine and its analogs., Yuan CH, Sun LR, Zhang M, Li SJ, Wang XM, Gao TM, Zhu XH., 2011
- Proteomic and Peptidomic Characterization of the Venom from the Chinese Bird Spider, Ornithoctonus huwena Wang., Yuan C, Jin Q, Tang X, Hu W, Cao R, Yang S, Xiong J, Xie C, Xie J, Liang S., 2007
