Professor | Qingtong Zhou | Asia Growth Partners

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Name	Qingtong Zhou
Contact Information	zhouqt@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Qingtong Zhou

Contact Information

zhouqt@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2005.09—2009.06 Bachelor's Degree in Polymer Chemistry: University of Science and Technology of China 2009.09—2015.06 Ph.D. in Polymer Chemistry and Physics: University of Science and Technology of China 2012.09—2014.09 Joint Ph.D. Student in Chemistry and Biochemistry: Harvard University 2019.09—2019.12 Visiting Scholar: KU Leuven Cancer Research Center
Work Experience	2015.07—2018.09 - ShanghaiTech University iHuman Institute - Postdoctoral Researcher 2018.10—2020.06 - ShanghaiTech University iHuman Institute - Research Assistant Professor 2020.07—Present - Fudan University School of Basic Medical Sciences - Junior Researcher
Awards	2018 - National Natural Science Foundation of China Youth Project: Principal Investigator 2016 - China Postdoctoral Science Foundation: Principal Investigator

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2005.09—2009.06 Bachelor's Degree in Polymer Chemistry: University of Science and Technology of China
2009.09—2015.06 Ph.D. in Polymer Chemistry and Physics: University of Science and Technology of China
2012.09—2014.09 Joint Ph.D. Student in Chemistry and Biochemistry: Harvard University
2019.09—2019.12 Visiting Scholar: KU Leuven Cancer Research Center

Work Experience

2015.07—2018.09 - ShanghaiTech University iHuman Institute - Postdoctoral Researcher
2018.10—2020.06 - ShanghaiTech University iHuman Institute - Research Assistant Professor
2020.07—Present - Fudan University School of Basic Medical Sciences - Junior Researcher

Awards

2018 - National Natural Science Foundation of China Youth Project: Principal Investigator
2016 - China Postdoctoral Science Foundation: Principal Investigator

Areas of Focus	Structure and Function of G Protein-Coupled Receptors Drug Screening and Design for Important Protein Targets
Publications	Searching the Sequence Space for Potent Aptamers Using SELEX in Silico, Zhou, Q., Xia, X., Luo, Z., Liang, H., and Shakhnovich, E., 2015 Exploring the Mutational Robustness of Nucleic Acids by Searching Genotype Neighborhoods in Sequence Space, Zhou, Q., Sun, X., Xia, X., Fan, Z., Luo, Z., Zhao, S., Shakhnovich, E., and Liang, H., 2017 Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators, Song, G., Yang, D., Wang, Y., de Graaf, C., Zhou, Q., Jiang, S., Liu, K., Cai, X., Dai, A., Lin, G., et al., 2017 Common activation mechanism of class A GPCRs, Zhou, Q., Yang, D., Wu, M., Guo, Y., Guo, W., Zhong, L., Cai, X., Dai, A., Jang, W., Shakhnovich, E.I., et al., 2019 Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands, Tan, L., Zhou, Q., Yan, W., Sun, J., Kozikowski, A.P., Zhao, S., Huang, X.P., and Cheng, J., 2020 A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor, Sun, W., Chen, L.N., Zhou, Q., Zhao, L.H., Yang, D., Zhang, H., Cong, Z., Shen, D.D., Zhao, F., Zhou, F., et al., 2020 Structures of the human cholecystokinin receptors bound to agonists and antagonists, Zhang, X., He, C., Wang, M., Zhou, Q., Yang, D., Zhu, Y., Feng, W., Zhang, H., Dai, A., Chu, X., et al., 2021 Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors, Zhao, F., Zhou, Q., Cong, Z., Hang, K., Zou, X., Zhang, C., Chen, Y., Dai, A., Liang, A., Ming, Q., et al., 2022 Crystal structure of a constitutive active mutant of adenosine A2A receptor, Cui, M., Zhou, Q., Xu, Y., Weng, Y., Yao, D., Zhao, S., and Song, G., 2022 Structural perspective of class B1 GPCR signaling, Cong, Z., Liang, Y.L., Zhou, Q., Darbalaei, S., Zhao, F., Feng, W., Zhao, L., Xu, H.E., Yang, D., and Wang, M.W., 2022

Areas of Focus

Structure and Function of G Protein-Coupled Receptors
Drug Screening and Design for Important Protein Targets

Publications

Searching the Sequence Space for Potent Aptamers Using SELEX in Silico, Zhou, Q., Xia, X., Luo, Z., Liang, H., and Shakhnovich, E., 2015
Exploring the Mutational Robustness of Nucleic Acids by Searching Genotype Neighborhoods in Sequence Space, Zhou, Q., Sun, X., Xia, X., Fan, Z., Luo, Z., Zhao, S., Shakhnovich, E., and Liang, H., 2017
Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators, Song, G., Yang, D., Wang, Y., de Graaf, C., Zhou, Q., Jiang, S., Liu, K., Cai, X., Dai, A., Lin, G., et al., 2017
Common activation mechanism of class A GPCRs, Zhou, Q., Yang, D., Wu, M., Guo, Y., Guo, W., Zhong, L., Cai, X., Dai, A., Jang, W., Shakhnovich, E.I., et al., 2019
Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands, Tan, L., Zhou, Q., Yan, W., Sun, J., Kozikowski, A.P., Zhao, S., Huang, X.P., and Cheng, J., 2020
A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor, Sun, W., Chen, L.N., Zhou, Q., Zhao, L.H., Yang, D., Zhang, H., Cong, Z., Shen, D.D., Zhao, F., Zhou, F., et al., 2020
Structures of the human cholecystokinin receptors bound to agonists and antagonists, Zhang, X., He, C., Wang, M., Zhou, Q., Yang, D., Zhu, Y., Feng, W., Zhang, H., Dai, A., Chu, X., et al., 2021
Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors, Zhao, F., Zhou, Q., Cong, Z., Hang, K., Zou, X., Zhang, C., Chen, Y., Dai, A., Liang, A., Ming, Q., et al., 2022
Crystal structure of a constitutive active mutant of adenosine A2A receptor, Cui, M., Zhou, Q., Xu, Y., Weng, Y., Yao, D., Zhao, S., and Song, G., 2022
Structural perspective of class B1 GPCR signaling, Cong, Z., Liang, Y.L., Zhou, Q., Darbalaei, S., Zhao, F., Feng, W., Zhao, L., Xu, H.E., Yang, D., and Wang, M.W., 2022

G Protein-Coupled Receptors Structure Function Drug Screening Design Protein Targets Neuroscience Molecular Mechanisms Pharmacology Biochemistry

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