Professor | Pingping Shen | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Pingping Shen
Contact Information	ppshen@nju.edu.cn
Language ability	Chinese, English
Province	Jiangsu

Upload Avatar (500 x 500)

Name

Pingping Shen

Contact Information

ppshen@nju.edu.cn

Language ability

Chinese, English

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing University
Faculty	Life Sciences
Academic Background & Achievements	Selected for the Ministry of Education's New Century Excellent Talents Program in 2006 Received over 30 grants including National Key R&D Program, NSFC Major Research Plan
Work Experience	Current - Nanjing University Model Animal Research Center - Principal Investigator
Awards	2014: Jiangsu Province Science and Technology First Prize 12th World Congress on Advances in Oncology: Outstanding Achievement Award

University/Lab Affiliation and Title

Nanjing University

Faculty

Life Sciences

Academic Background & Achievements

Selected for the Ministry of Education's New Century Excellent Talents Program in 2006
Received over 30 grants including National Key R&D Program, NSFC Major Research Plan

Work Experience

Current - Nanjing University Model Animal Research Center - Principal Investigator

Awards

2014: Jiangsu Province Science and Technology First Prize
12th World Congress on Advances in Oncology: Outstanding Achievement Award

Areas of Focus	Macrophage immune regulation and related immunotherapy technologies Reprogramming of macrophage functions
Publications	Intervening pyruvate carboxylase stunts tumor growth by strengthening anti-tumor actions of tumor-associated macrophages., Y.X. Shu, N.F. Yang, N. Cheng, Z.Y. Zou, W.L. Zhang, Y.C. Bei, Q. Shi, M.H. Qin, W.G. Zhu, P.P. Shen, 2022 Blockage of PPARγ T166 phosphorylation enhances the inducibility of beige adipocytes and improves metabolic dysfunctions., N.F. Yang, Y.X. Wang, Q. Tian, Q.P. Wang, Y. Lu, L.C. Sun, S.J. Wang, Y.C. Bei, J.G. Ji, H. Zhou, W. Yang, P.J. Yao, W.Y. Zhu, L.Y. Sun, Z.F. Huang, X.K. Li, P.P. Shen, 2023 Caspase-1 cleaves PPARγ for potentiating the pro-tumor action of TAMs., Z.Y. Niu, Q. Shi, W.L. Zhang, B. Chen, Q.S. Wang, X.Y. Zhao, J.J. Chen, Y.X. Shu, N. Cheng, X.J. Feng, J.G. Ji, P.P. Shen, 2017 CDK5 Inhibition Abrogates TNBC Stem-cell Property and Enhances Anti-PD-1 Therapy., Y.C. Bei, N. Cheng, T. Chen, Y.X. Shu, Y. Yang, N.F. Yang, X.Y. Zhou, B.R. Liu, J. Wei, Q. Liu, W. Zheng, W.L. Zhang, H.F. Su, W.G. Zhu, J.G. Ji, P.P. Shen, 2020 Crosstalk between IL-15Rα+ tumor-associated macrophages and breast cancer cells reduces CD8+ T cell recruitment., W.L. Zhang, Q. Zhang, N.F. Yang, Q. Shi, H.F. Su, T.S. Lin, Z.L. He, W.X. Wang, H.Q. Guo, P.P. Shen, 2022 Treatment of obesity-related inflammation with a novel synthetic pentacyclic oleanane triterpenoids via modulation of macrophage polarization., N.F. Yang, Q. Tang, W.T. Qin, Z.Y. Li, D.D. Wang, W.J. Zhang, X. Cao, Y. Lu, X.Y. Ge, H.B. Sun, P.P. Shen, 2019 An ultrasensitive electrochemical immunosensor for procalcitonin detection based on the gold nanoparticles-enhanced tyramide signal amplification strategy., P. Liu, C. Li, R.X. Zhang, Q. Tang, J. Wei, Y. Lu, P.P. Shen, 2019 Porous Silicon Nanocarriers Boost the Immunomodulation of Mitochondria Targeted Bovine Serum Albumins on Macrophage Polarization., J.L. Li, J.Q. Fan, Y. Gao, S.D. Huang, D. Huang, J.C. Li, X.Y. Wang, Hélder A. Santos, P.P. Shen, B. Xia, 2023 Establishment of a novel mesenchymal stem cell-based regimen for chronic myeloid leukemia differentiation therapy., S.M. Zuo, L.C. Sun, Y.X. Wang, B. Chen, J.Y. Wang, X.Y. Ge, Y. Lu, N.F. Yang, P.P. Shen, 2021 Chimeric antigen receptor macrophage therapy for breast tumours mediated by targeting the tumour extracellular matrix., W.L. Zhang, L. Liu, H.F. Su, Q. Liu, J. Shen, H.R. Dai, W. Zheng, Y. Lu, W.J. Zhang, Y.C. Bei, P.P. Shen, 2019

Areas of Focus

Macrophage immune regulation and related immunotherapy technologies
Reprogramming of macrophage functions

Publications

Intervening pyruvate carboxylase stunts tumor growth by strengthening anti-tumor actions of tumor-associated macrophages., Y.X. Shu, N.F. Yang, N. Cheng, Z.Y. Zou, W.L. Zhang, Y.C. Bei, Q. Shi, M.H. Qin, W.G. Zhu, P.P. Shen, 2022
Blockage of PPARγ T166 phosphorylation enhances the inducibility of beige adipocytes and improves metabolic dysfunctions., N.F. Yang, Y.X. Wang, Q. Tian, Q.P. Wang, Y. Lu, L.C. Sun, S.J. Wang, Y.C. Bei, J.G. Ji, H. Zhou, W. Yang, P.J. Yao, W.Y. Zhu, L.Y. Sun, Z.F. Huang, X.K. Li, P.P. Shen, 2023
Caspase-1 cleaves PPARγ for potentiating the pro-tumor action of TAMs., Z.Y. Niu, Q. Shi, W.L. Zhang, B. Chen, Q.S. Wang, X.Y. Zhao, J.J. Chen, Y.X. Shu, N. Cheng, X.J. Feng, J.G. Ji, P.P. Shen, 2017
CDK5 Inhibition Abrogates TNBC Stem-cell Property and Enhances Anti-PD-1 Therapy., Y.C. Bei, N. Cheng, T. Chen, Y.X. Shu, Y. Yang, N.F. Yang, X.Y. Zhou, B.R. Liu, J. Wei, Q. Liu, W. Zheng, W.L. Zhang, H.F. Su, W.G. Zhu, J.G. Ji, P.P. Shen, 2020
Crosstalk between IL-15Rα+ tumor-associated macrophages and breast cancer cells reduces CD8+ T cell recruitment., W.L. Zhang, Q. Zhang, N.F. Yang, Q. Shi, H.F. Su, T.S. Lin, Z.L. He, W.X. Wang, H.Q. Guo, P.P. Shen, 2022
Treatment of obesity-related inflammation with a novel synthetic pentacyclic oleanane triterpenoids via modulation of macrophage polarization., N.F. Yang, Q. Tang, W.T. Qin, Z.Y. Li, D.D. Wang, W.J. Zhang, X. Cao, Y. Lu, X.Y. Ge, H.B. Sun, P.P. Shen, 2019
An ultrasensitive electrochemical immunosensor for procalcitonin detection based on the gold nanoparticles-enhanced tyramide signal amplification strategy., P. Liu, C. Li, R.X. Zhang, Q. Tang, J. Wei, Y. Lu, P.P. Shen, 2019
Porous Silicon Nanocarriers Boost the Immunomodulation of Mitochondria Targeted Bovine Serum Albumins on Macrophage Polarization., J.L. Li, J.Q. Fan, Y. Gao, S.D. Huang, D. Huang, J.C. Li, X.Y. Wang, Hélder A. Santos, P.P. Shen, B. Xia, 2023
Establishment of a novel mesenchymal stem cell-based regimen for chronic myeloid leukemia differentiation therapy., S.M. Zuo, L.C. Sun, Y.X. Wang, B. Chen, J.Y. Wang, X.Y. Ge, Y. Lu, N.F. Yang, P.P. Shen, 2021
Chimeric antigen receptor macrophage therapy for breast tumours mediated by targeting the tumour extracellular matrix., W.L. Zhang, L. Liu, H.F. Su, Q. Liu, J. Shen, H.R. Dai, W. Zheng, Y. Lu, W.J. Zhang, Y.C. Bei, P.P. Shen, 2019

Macrophage Immune Regulation Immunotherapy Reprogramming Tumor Metabolism Gene Editing Chemical Intervention Tumor Microenvironment Biological Synthesis

Yanhe Li - Tongji University

Gao Rui - Tongji University

Bing Du - East China Normal University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us