Graduated from Nanjing University with Bachelor's, Master's, and Doctorate degrees
Lead instructor for 'Biochemistry' at Nanjing University
Editor of national and provincial level textbooks
2019: First Prize in Higher Education Scientific Research Outstanding Achievement Award (Science and Technology)
2014: Jiangsu Province 'Six Talent Peaks' High-Level Talent Training Program A Class
Research
Pathological mechanisms of metabolic syndrome kidney injury and protective effects of active components of traditional Chinese medicine Mechanisms of podocyte injury induced by metabolic reprogramming
Pterostilbene Attenuates Fructose-Induced Myocardial Fibrosis by Inhibiting ROS-Driven Pitx2c/miR-15b Pathway., Kang Linlin, Zhang Dongmei, Jiao Ruiqing, Pan Shuman, Zhao Xiaojuan, Zheng Yanjing, Chen Tianyu, Kong Lingdong, 2019
Mediation of Extracellular Polymeric Substances in Microbial Reduction of Hematite by Shewanella oneidensis MR-1., Gao Lei, Lu Xiancai, Liu Huan, Li Juan, Li Weijie, Song Rongbin, Wang Ruiyong, Zhang Dongmei, Zhu Junjie, 2019
Pterostilbene alleviates fructose-induced renal fibrosis by suppressing TGF-beta1/TGF-beta type I receptor/Smads signaling in proximal tubular epithelial cells., Gu, Ting-Ting, Chen, Tian-Yu, Yang, Yan-Zi, Zhao, Xiao-Juan, Sun, Yang, Li, Tu-Shuai, Zhang, Dong-Mei, Kong, Ling-Dong, 2018
Multi-Responsive Supramolecular Theranostic Nanoplatform Based on Pillar[5]arene and Diphenylboronic Acid Derivatives for Integrated Glucose Sensing and Insulin Delivery., Minzan Zuo, Weirui Qian, Zuqiang Xu, Wei Shao, Xiao-Yu Hu, Dongmei Zhang, Juli Jiang, Xiaoqiang Sun, and Leyong Wang, 2018
bifA Regulates Biofilm Development of Pseudomonas putida MnB1 as a Primary Response to H2O2 and Mn2+., Yanjing Zheng, Yumei Li, Hongyan Long, Xiaojuan Zhao, Keke Jia, Juan Li, Leyong Wang, Ruiyong Wang, Xiancai Lu and Dongmei Zhang, 2018
Dual-Responsive Bola-Type Supra-Amphiphile Constructed from Water-Soluble Pillar[5]arene and Naphthalimide-Containing Amphiphile for Intracellular Drug Delivery., Lin, Xin, Jia, Keke, Wang, Yichen, Shao, Wei, Yao, Chenhao, Peng, Luming, Zhang, Dongmei, Hu, Xiao-Yu, Wang, Leyong, 2017
Glucose-Responsive Supramolecular Vesicles Based on Water- Soluble Pillar[5]arene and Pyridylboronic Acid Derivatives for Controlled Insulin Delivery., Gao Lei, Wang Tingting, Jia Keke, Wu Xuan, Yao Chenhao, Shao Wei, Zhang Dongmei, Hu XiaoYu, and Wang Leyong, 2017
High Dietary Fructose: Direct or Indirect Dangerous Factors Disturbing Tissue and Organ Functions., Zhang Dong-Mei, Jiao Rui-Qing, Ling-Dong Kong, 2017
Fructose down-regulates miR-330 to induce renal inflammatory response and insulin signaling impairment: Attenuation by morin., Gu Ting-Ting, Song Lin, Chen Tian-Yu, Wang Xing, Zhao Xiao-Juan, Ding Xiao-Qin, Yang Yan-Zi, Pan Ying, Zhang Dong-Mei, Kong Ling-Dong, 2017
Cinnamaldehyde and allopurinol reduce fructose-induced cardiac inflammation and fibrosis by attenuating CD36-mediated TLR4/6-IRAK4/1 signaling to suppress NLRP3 inflammasome activation., Kang Lin-Lin, Zhang Dong-Mei, Ma Chun-Hua, Zhang Jian-Hua, Jia Ke-Ke, Liu Jia-Hui, Wang Rong, Kong Ling-Dong, 2016
Simiao pill ameliorates renal glomerular injury via increasing Sirt1 expression and suppressing NF-kappaB/NLRP3 inflammasome activation in high fructose-fed rats., Ma Chun-Hua, Kang Lin-Lin, Ren Hong-Mei, Zhang Dong-Mei, Kong Ling-Dong, 2015
Wuling San protects kidney dysfunction by inhibiting renal TLR4/MyD88 signaling and NLRP3 inflammasome activation in high fructose-induced hyperuricemic mice., Yang Ying, Zhang Dong-Mei, Liu Jia-Hui, Hu Lin-Shui, Xue Qiao-Chu, Ding Xiao-Qin, Kong Ling-Dong, 2015
The adverse effects of long-term l-carnitine supplementation on liver and kidney function in rats., Liu Lei, Zhang Dong-Mei, Wang Ming-Xing, Fan Chen-Yu, Zhou Fan, Wang Shui-Juan, Kong Ling-Dong, 2015
Nuciferine restores potassium oxonate-induced hyperuricemia and kidney inflammation in mice., Wang Ming-Xing, Liu Yang-Liu, Yang Ying, Zhang Dong-Mei, Kong Ling-Dong, 2015
Dual photo- and pH-responsive supramolecular nanocarriers based on water-soluble pillar[6]arene and different azobenzene derivatives for intracellular anticancer drug delivery., Hu Xiao-Yu, Jia Ke-Ke, Cao Yu, Li Yan, Qin Shan, Zhou Fan, Lin Chen, Zhang Dong-Mei, Wang Leyong, 2015
Morin reduces hepatic inflammation-associated lipid accumulation in high fructose-fed rats via inhibiting sphingosine kinase 1/sphingosine phosphate signaling pathway., Wang Xing, Zhang Dong-Mei, Gu Ting-Ting, Ding Xiao-Qin, Fan Chen-Yu, Zhu Qin, Shi Yun-Wei, Hong Ye, Kong Ling-Dong, 2013
Bigelovii A induces apoptosis of HL‑60 human acute promyelocytic leukaemia cells., Guan Fu-Qin, Wang Hai-Ting, Shan Yu, Zhang Dong-Mei, Zhao You-Yi, Chen Yu, Wang Qi-Zhi, Wang Ming, Feng Xu, 2013
Protection of curcumin against fructose-induced hyperuricaemia and renal endothelial dysfunction involves NO-mediated JAK-STAT signalling in rats., Zhang Dong-Mei, Li Yu-Cheng, Xu De, Ding Xiao-Qin, Kong Ling-Dong, 2012
Study of Hemoglobin and Human Serum Albumin Glycation with Electrochemical Techniques., Yang Jing-Hua, Zhao Jing, Xiao Han, Zhang Dong-Mei, Li Gen-Xi, 2010
Icariin attenuates chronic mild stress-induced dysregulation of the LHPA stress circuit in rats., Pan Ying, Wang Fu-Meng, Qiang Li-Qin, Zhang Dong-Mei, Kong Ling-Dong, 2010
Iron-containing lipoprotein SiaA in SiaABC, the primary heme transporter of Streptococcus pyogenes., Sun Xue-Song, Ge Rui-Guang, Zhang Dong-Mei, Sun Hong-Zhe, He Qing-Yu, 2010
Novel Method to Detect DNA Methylation Using Gold Nanoparticles Coupled with Enzyme-Linkage Reactions., Liu Tao, Zhao Jing, Zhang Dong-Mei, Li Gen-Xi, 2010
Allopurinol, rutin and quercetin attenuate hyperuricemia and renal dysfunction in rats induced by fructose intake: renal organic ion transporter involvement., Hu Qing-Hua, Wang Chuang, Li Jian-Mei, Zhang Dong-Mei, Kong Ling-Dong, 2009
Hemolysate-induced Expression of Intercellular Adhesion Molecule-1 and Monocyte Chemoattractant Protein-1 Expression in Cultured Brain Microvascular Endothelial Cells via Through ROS-dependent NF-κB Pathways., Lu Hua, Shi Ji-Xin, Zhang Dong-Mei, Shen Jie, Lin Yi-Xing, Hang Chun-Hua, Yin Hong-Xia, 2009
GSH-dependent iNOS and HO-1 Mediated Apoptosis of Human Jurkat Cells Induced by Nickel(II)., Zhang Dong-Mei, Shen Jie, Wang Cui-Cui, Zhang Xin, Chen Jun-Hui, 2009
Protein-based voltammetric biosensors fabricated with nanomaterials., Zhang Dong-Mei, Zhao Jing, Li Gen-Xi, 2008
Electrochemical Assay of Human Islet Amyloid Polypeptide and Its Aggregation., Zhou Nan-Di, Chen Zhen-Yu, Zhang Dong-Mei, Li Gen-Xi, 2008
An approach to assay the enzymatic activity of calcineurin and the inhibitory effect of zinc ion., Huang Jun-Yi, Zhang Dong-Mei, Xing Wei, Ma Xiang, Yin Yan-Xia, Wei Qun, Li Gen-Xi, 2008
Binding of Ni2+ to a histidine- and glutamine-rich protein, Hpn-like., Zeng Yi-Bo, Zhang Dong-Mei, Li Hong-Yan, Sun Hong-Zhe, 2008
Electrochemical study of the inhibitory effect of sinapic acid and its derivatives on tyrosinase reactivity., Zhang Dong-Mei, Zhou Nan-Di, Zhou Hhui, Chen Ting, Li Gen-Xi, 2008
Nitric Oxide and Bcl-2 Mediated the Apoptosis Induced by Nickel(II) in Human T Hybridoma Cells., Guan Fu-Qin, Zhang Dong-Mei, Wang Xin-Chang, Chen Jun-Hui, 2007
An electrochemical method to detect folate receptor positive tumor cells., Liu Lei, Zhu Xiao-Li, Zhang Dong-Mei, Huang Jun-Yi, Li Gen-Xi, 2007
Hypouricemic action of selected flavonoids in mice structure-activity relationships., Mo Shi-Fu, Zhou Feng, Lv Yao-Zhong, Hu Qing-Hua, Zhang Dong-Mei, Kong Ling-Dong, 2007
Keywords
Metabolic SyndromeKidney InjuryTraditional Chinese MedicinePathological MechanismsProtective EffectsPodocyte InjuryMetabolic ReprogrammingRenal FibrosisBiochemistryPharmacology
Area of Focus
Drug Targets | Pathogenesis | Molecular Mechanisms | Protein Research | Drug Discovery | Drug Development | Structural Biology | Biochemistry | Molecular Biology | Pharmacology
