2010-09 to 2018-01: Ph.D. in Cell Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
2006-09 to 2010-06: Bachelor's in Biological Sciences, Shandong University
2024-08 to Present: Assistant Professor, Nanjing University
2022-12 to 2024-07: Research Associate, Perelman School of Medicine, University of Pennsylvania
2017-12 to 2022-11: Postdoctoral Researcher, Perelman School of Medicine, University of Pennsylvania
2017: Outstanding Graduate, University of Chinese Academy of Sciences
2017: President's Excellence Scholarship, Chinese Academy of Sciences
2015: Hengyuanxiang Talent Second Prize
2015: Yihai Kerry Scholarship, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
2015: Procter & Gamble Excellent Graduate Student Scholarship, Chinese Academy of Sciences
2014: National Scholarship for Doctoral Students
2009: Weichai Power Scholarship, Shandong University
2007 & 2008: Second Prize Scholarship for Outstanding Students, Shandong University
Research
Epitranscriptomic regulation mechanisms in neurodevelopment using mouse and human brain organoid models
m(6)A/YTHDF2-mediated mRNA decay targets TGF-beta signaling to suppress the quiescence acquisition of early postnatal mouse hippocampal NSCs., Zhang, F.*, Fu, Y., Jimenez-Cyrus, D., Zhao, T., Shen, Y., Sun, Y., Zhang, Z., Wang, Q., Kawaguchi, R., Geschwind, D.H., He C., Ming, G.L., and Song, H., 2024
Epitranscriptomic regulation of cortical neurogenesis via Mettl8-dependent mitochondrial tRNA m(3)C modification., Zhang, F.*, Yoon, K., Zhang, D.Y., Kim, N.S., Ming, G.L., and Song, H., 2023
Cell-autonomous and non-cell-autonomous roles of NKCC1 in regulating neural stem cell quiescence in the hippocampal dentate gyrus., Zhang, F.*, Yoon, K., Kim, N., Ming, G., and Song, H., 2023
Advances in brain epitranscriptomics research and translational opportunities., Zhang, F.*, Ignatova, V.V.*, Ming, G.L., and Song, H., 2023
cTAGE5/MEA6 plays a critical role in neuronal cellular components trafficking and brain development., Zhang, F.*, Wang, Y.*, Wang, T., Yao, L., Lam, S.M., Huang, X., Fan, J., Wang, Q., Liu, L., Jiang, Y., Zhang, H., Shi, L., Yu, M., Shui, G., Wang, Y., Gao, F., Zhang, X. and Xu, Z., 2018
A single mutation in the prM protein of Zika virus contributes to fetal microcephaly., Yuan, L.*, Huang, X.Y.*, Liu, Z.Y.*, Zhang, F.*, Zhu, X.L.*, Yu, J.Y.*, Ji, X., Xu, Y.P., Li, G., Li, C.,Wang, H. J., Deng, Y. Q., Wu, M., Cheng, M. L., Ye, Q., Xie, D. Y., Li, X. F., Wang, X., Shi, W., Hu, B., Shi, P. Y., Xu, Z. and Qin, C. F., 2017
American Strain of Zika Virus Causes More Severe Microcephaly than an Old Asian Strain in neonatal Mice., Zhang, F.*, Wang, H.*, Wang, Q.*, Liu, Z.*, Yuan, L.*, Huang, X.*, Li, G., Ye, Q., Yang, H., Shi, L., Deng, Y. Q., Qin, C. F. and Xu, Z., 2017
A Novel c-Jun N-terminal Kinase (JNK) Signaling Complex Involved in Neuronal Migration during Brain Development., Zhang, F.*, Yu, J., Yang, T., Xu, D., Chi, Z., Xia, Y., and Xu, Z., 2016
Epigenetic regulation of Atrophin1 by lysine-specific demethylase 1 is required for cortical progenitor maintenance., Zhang, F.*, Xu, D., Yuan, L., Sun, Y., and Xu, Z., 2014
TAK1 is activated by TGF-beta signaling and controls axonal growth during brain development., Yu, J.*, Zhang, F.*, Wang, S., Zhang, Y., Fan, M., and Xu, Z., 2014
Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation., Muneer, A.*, Wang, L.*, Xie, L.*, Zhang, F., Wu, B., Mei, L., Lenarcic, E.M., Feng, E.H., Song, J., Xiong, Y., Yu, X., Wang, C., Jain, K., Strahl, B. D., Cook, J. G., Wan, Y. Y., Moorman, N. J., Song, H., Jin, J. and Chen, X., 2023
POSH regulates assembly of the NMDAR/PSD-95/Shank complex and synaptic function., Yao, M.*, Meng, M., Yang, X., Wang, S., Zhang, H., Zhang, F., Shi, L., Zhang, Y., Zhang, X., and Xu, Z., 2022
Molecular mechanisms underlying cTAGE5/MEA6-mediated cargo transport and biological functions., Ma, T.*, Zhang, F., Wang, Y., Xu, Z., 2022
Generation of hypothalamic arcuate organoids from human induced pluripotent stem cells., Huang, W.*, Wong, S.*, Pather, S.*, Nguyen, P., Zhang, F., Zhang, D., Zhang, Z., Lu, L., Fang, W., Chen, L., Fernandes, A., Su, Y., Song, H. and Ming, G. L., 2021
Human pluripotent stem cell-derived neural cells and brain organoids reveal SARS-CoV-2 neurotropism predominates in choroid plexus epithelium., Jacob, F*, Pather, S., Huang, W. Zhang, F., Wong, S., Zhou, H., Cubitt, B., Fan, W., Chen, C. Z., Xu, M., Pradhan, M., Zhang, D. Y., Zheng, W., Bang, A. G., Song, H., Carlos de la Torre, J. and Ming, G. L., 2020
Different gene networks are disturbed by Zika virus infection in a mouse microcephaly model., Chang, Y.*, Jiang, Y.*, Li, C., Wang, Q., Zhang, F., Qin, C., Wu, Q., Li, J., Xu, Z., 2020
m6A facilitates hippocampus-dependent learning and memory through YTHDF1., Shi, H.*, Zhang, X.*, Weng, Y.*, Lu, Z., Liu, Y., Lu, Z., Li, J., Hao, P., Zhang, Y., Zhang, F., Wu, Y., Delgado, J. Y., Su, Y., Patel, M. J., Cao, X., Shen, B., Huang, X., Ming, G. L., Zhuang, X., Song, H., He, C. and Zhou, T., 2018
MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis., Xu, D.*, Yao, M.*, Wang, Y.*, Yuan, L.*, Hoeck, J.D.*, Yu, J., Liu, L., Yeap, Y.Y.C., Zhang, W., Zhang, F., Feng, Y., Ma, T., Wang, Y., Ng, D. C. H., Niu, X., Su, B., Behrens, A. and Xu, Z., 2018
cTAGE5 deletion in pancreatic beta cells impairs proinsulin trafficking and insulin biogenesis in mice., Fan, J.*, Wang, Y.*, Liu, L., Zhang, H., Zhang, F., Shi, L., Yu, M., Gao, F., and Xu, Z., 2017
Mea6 controls VLDL transport through the coordinated regulation of COPII assembly., Wang, Y.*, Liu, L.*, Zhang, H., Fan, J., Zhang, F., Yu, M., Shi, L., Yang, L., Lam, S.M., Wang, H., Chen, X., Wang, Y., Gao, F., Shui, G. and Xu, Z., 2016
The B-cell receptor BR3 modulates cellular branching via Rac1 during neuronal migration., Zhang, L.*, Zhang, F., Yang, T., Zhu, X., Zheng, N., Li, H., Zhu, D., Zhu, Y., and Xu, Z., 2016
MAZ mediates the cross-talk between CT-1 and NOTCH1 signaling during gliogenesis., Liu, B.*, Ma, A., Zhang, F., Wang, Y., Li, Z., Li, Q., Xu, Z., and Zheng, Y., 2016
Microcephaly-associated protein WDR62 regulates neurogenesis through JNK1 in the developing neocortex., Xu, D.*, Zhang, F., Wang, Y., Sun, Y., and Xu, Z., 2014
POSH localizes activated Rac1 to control the formation of cytoplasmic dilation of the leading process and neuronal migration., Yang, T.*, Sun, Y., Zhang, F., Zhu, Y., Shi, L., Li, H., and Xu, Z., 2012
The suppression of CRMP2 expression by bone morphogenetic protein (BMP)-SMAD gradient signaling controls multiple stages of neuronal development., Sun, Y.*, Fei, T.*, Yang, T.*, Zhang, F., Chen, Y.G., Li, H., and Xu, Z., 2010
