Professor | Wenyuan Han | Asia Growth Partners

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Name	Wenyuan Han
Contact Information	hanwenyuan@mail.hzau.edu.cn
Language ability	Chinese, English
Province	Hubei

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Name

Wenyuan Han

Contact Information

hanwenyuan@mail.hzau.edu.cn

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Huazhong Agricultural University
Faculty	Life Sciences
Academic Background & Achievements	2004.09-2011.07 Bachelor/Master of Science: Shandong University 2011.09-2015.05 PhD in Science: University of Copenhagen
Work Experience	2015.08-2017.07 - University of Copenhagen - Postdoctoral Researcher 2017.07-2018.03 - University of Copenhagen - Assistant Professor 2018.09-present - Huazhong Agricultural University - Professor

University/Lab Affiliation and Title

Huazhong Agricultural University

Faculty

Life Sciences

Academic Background & Achievements

2004.09-2011.07 Bachelor/Master of Science: Shandong University
2011.09-2015.05 PhD in Science: University of Copenhagen

Work Experience

2015.08-2017.07 - University of Copenhagen - Postdoctoral Researcher
2017.07-2018.03 - University of Copenhagen - Assistant Professor
2018.09-present - Huazhong Agricultural University - Professor

Areas of Focus	Microbial immune systems Application technologies based on microbial immune systems
Publications	A short prokaryotic Argonaute activates membrane effector to confer antiviral defense., Zhifeng Zeng, Yu Chen, Rafael Pinilla-Redondo, Shiraz A. Shah, Fen Zhao, Chen Wang, Zeyu Hu, Chang Wu, Changyi Zhang, Rachel J. Whitaker, Qunxin She, Wenyuan Han, 2022 The trans DNA cleavage activity of Cas12a provides no detectable immunity against plasmid or phage., Shunhang Liu, Xichen Rao, Ruiliang Zhao, Wenyuan Han, 2022 A membrane-associated DHH-DHHA1 nuclease degrades type III CRISPR second messenger., Ruiliang Zhao, Yang Yang, Fan Zheng, Zhifeng Zeng, Wenqian Feng, Xuexia Jin, Jiayi Wang, Ke Yang, Yun Xiang Liang, Qunxin She, Wenyuan Han, 2020 Cmr3 regulates the suppression on cyclic oligoadenylate synthesis by tag complementarity in a Type III-B CRISPR-Cas system., Tong Guo, Fan Zheng, Zhifeng Zeng, Yang Yang, Qi Li, Qunxin She, Wenyuan Han, 2019 A Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding., Wenyuan Han, Stefano Stella, Yan Zhang, Tong Guo, Karolina Sulek, Li Peng-Lundgren, Guillermo Montoya, Qunxin She, 2018 Tolerance of Sulfolobus SMV1 virus to the immunity of I-A and III-B CRISPR-Cas systems in Sulfolobus islandicus., Tong Guo, Wenyuan Han, Qunxin She, 2019 Allosteric regulation of Csx1, a type IIIB-associated CARF domain ribonuclease by RNAs carrying a tetraadenylate tail., Wenyuan Han, Saifu Pan, Blanca Lopez-Mendez, Guillermo Montoya, Qunxin She, 2017 A type III-B CRISPR-Cas effector complex mediating massive target DNA destruction., Wenyuan Han, Yingjun Li, Ling Deng, Mingxia Feng, Wenfang Peng, Søren Hallstrøm, Jing Zhang, Nan Peng, Yun Xiang Liang, Malcolm F. White, Qunxin She, 2017 NQO-induced DNA-less cell formation is associated with chromatin protein degradation and dependent on A0A1-ATPase in Sulfolobus., Wenyuan Han, Yanqun Xu, Xu Feng, Yun Xiang Liang, Li Huang, Yulong Shen, Qunxin She, 2017 Reverse gyrase functions in genome integrity maintenance by protecting DNA breaks in vivo., Wenyuan Han, Xu Feng, Qunxin She, 2017 CRISPR history: discovery, characterization, application and prosperity., Wenyuan Han, Qunxin She, 2017 Nanobiomotors of archaeal DNA repair machineries: current research status and application potential., Wenyuan Han, Yulong Shen, Qunxin She, 2014 Knockouts of RecA-like proteins RadC1 and RadC2 have distinct responses to DNA damage agents in Sulfolobus islandicus., Pengjuan Liang, Wenyuan Han, Qihong Huang, Yanze Li, Jinfeng Ni, Qunxin She, Yulong Shen, 2013

Areas of Focus

Microbial immune systems
Application technologies based on microbial immune systems

Publications

A short prokaryotic Argonaute activates membrane effector to confer antiviral defense., Zhifeng Zeng, Yu Chen, Rafael Pinilla-Redondo, Shiraz A. Shah, Fen Zhao, Chen Wang, Zeyu Hu, Chang Wu, Changyi Zhang, Rachel J. Whitaker, Qunxin She, Wenyuan Han, 2022
The trans DNA cleavage activity of Cas12a provides no detectable immunity against plasmid or phage., Shunhang Liu, Xichen Rao, Ruiliang Zhao, Wenyuan Han, 2022
A membrane-associated DHH-DHHA1 nuclease degrades type III CRISPR second messenger., Ruiliang Zhao, Yang Yang, Fan Zheng, Zhifeng Zeng, Wenqian Feng, Xuexia Jin, Jiayi Wang, Ke Yang, Yun Xiang Liang, Qunxin She, Wenyuan Han, 2020
Cmr3 regulates the suppression on cyclic oligoadenylate synthesis by tag complementarity in a Type III-B CRISPR-Cas system., Tong Guo, Fan Zheng, Zhifeng Zeng, Yang Yang, Qi Li, Qunxin She, Wenyuan Han, 2019
A Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding., Wenyuan Han, Stefano Stella, Yan Zhang, Tong Guo, Karolina Sulek, Li Peng-Lundgren, Guillermo Montoya, Qunxin She, 2018
Tolerance of Sulfolobus SMV1 virus to the immunity of I-A and III-B CRISPR-Cas systems in Sulfolobus islandicus., Tong Guo, Wenyuan Han, Qunxin She, 2019
Allosteric regulation of Csx1, a type IIIB-associated CARF domain ribonuclease by RNAs carrying a tetraadenylate tail., Wenyuan Han, Saifu Pan, Blanca Lopez-Mendez, Guillermo Montoya, Qunxin She, 2017
A type III-B CRISPR-Cas effector complex mediating massive target DNA destruction., Wenyuan Han, Yingjun Li, Ling Deng, Mingxia Feng, Wenfang Peng, Søren Hallstrøm, Jing Zhang, Nan Peng, Yun Xiang Liang, Malcolm F. White, Qunxin She, 2017
NQO-induced DNA-less cell formation is associated with chromatin protein degradation and dependent on A0A1-ATPase in Sulfolobus., Wenyuan Han, Yanqun Xu, Xu Feng, Yun Xiang Liang, Li Huang, Yulong Shen, Qunxin She, 2017
Reverse gyrase functions in genome integrity maintenance by protecting DNA breaks in vivo., Wenyuan Han, Xu Feng, Qunxin She, 2017
CRISPR history: discovery, characterization, application and prosperity., Wenyuan Han, Qunxin She, 2017
Nanobiomotors of archaeal DNA repair machineries: current research status and application potential., Wenyuan Han, Yulong Shen, Qunxin She, 2014
Knockouts of RecA-like proteins RadC1 and RadC2 have distinct responses to DNA damage agents in Sulfolobus islandicus., Pengjuan Liang, Wenyuan Han, Qihong Huang, Yanze Li, Jinfeng Ni, Qunxin She, Yulong Shen, 2013

Crispr-Cas9 Gene Editing Gene Expression Regulation Nucleic Acid Detection Virus Invasion Plasmid Invasion Immune Mechanisms Argonaute Bacteria Archaea

Chengying Jiang - University of Chinese Academy of Sciences

Jie Li - University of Chinese Academy of Sciences

Rui Zhang - Sun Yat-Sen University

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