Areas of Focus
- Microbial functional genes and protein engineering
Work Experience
- 2006/01 - Present, Sun Yat-sen University, School of Life Sciences, Professor
- 2001/01 - 2005/12, Sun Yat-sen University, School of Life Sciences, Associate Professor
- 1996/01 - 2000/12, Sun Yat-sen University, School of Life Sciences, Lecturer
- 1991/01 - 1995/12, Sun Yat-sen University, School of Life Sciences, Assistant
Academic Background & Achievements
- Published over 40 SCI papers
- Received 8 authorized invention patents
- 2016 Guangdong Province Science and Technology Progress Award, Second Prize
- 2015 Guangzhou Science and Technology Progress Award, Second Prize
Publications
- Engineering of β‑glucosidase bgl15 with simultaneously enhanced glucose tolerance and thermostability to improve its performance in high-solid cellulose hydrolysis., Lichuang Cao, Ran Chen, Xin Huang, Shuifeng Li, Sufang Zhang, Xiangpeng Yang, Zongmin Qin, Wei Kong, Wei Xie, and Yuhuan Liu, 2020
- Improving the cellobiose-hydrolysis activity and glucose-tolerance of a thermostable β-glucosidase through rational design., Xiwen Liu, Lichuang Cao, Jianhua Zeng, Yuhuan Liu, Wei Xie, 2019
- Improving Galactooligosaccharide Synthesis Efficiency of β‑Galactosidase Bgal1‑3 by Reshaping the Active Site with an Intelligent Hydrophobic Amino Acid Scanning., Zongmin Qin, Shuifeng Li, Xin Huang, Wei Kong, Xiangpeng Yang, Sufang Zhang, Lichuang Cao and Yuhuan Liu, 2019
- Tat-Independent Secretion of Polyethylene Terephthalate Hydrolase PETase in Bacillus subtilis 168 Mediated by Its Native Signal Peptide., Xin Huang, Lichuang Cao, Zongmin Qin, Shuifeng Li, Wei Kong, and Yuhuan Liu, 2018
- Enhancing the Thermostability of Highly Active and GlucoseTolerant β‑Glucosidase Ks5A7 by Directed Evolution for Good Performance of Three Properties., Lichuang Cao, Shuifeng Li, Xin Huang, Zongmin Qin, Wei Kong, Wei Xie, and Yuhuan Liu, 2018
- Improving the Secretion Yield of the β‑Galactosidase Bgal1‑3 in Pichia pastoris for Use as a Potential Catalyst in the Production of Prebiotic-Enriched Milk., Lichuang Cao, Guanghui Ren, Zongmin Qin, Xin Huang, Wei Kong, Zhijun Wang, Weiqu Liang, Xiaogang Bi, and Yuhuan Liu, 2017
- Structures of a glucose-tolerant β-glucosidase provide insights into its mechanism., Cao Li‑chuang, Liu Yu-huan, Xie Wei, and Wang Z., 2017
- Efficient Secretion of the β‑Galactosidase Bgal1‑3 via both Tat-Dependent and Tat-Independent Pathways in Bacillus subtilis., Guang-hui Ren, Li-chuang Cao, Wei Kong, Zhi-jun Wang, and Yu-huan Liu, 2016
- Engineering of a thermostable esterase Est816 to improve its quorum-quenching activity and the underlying structural basis., Xiwen Liu, Li-chuang Cao, Xin-jiong Fan, Yu-huan Liu & Wei Xie, 2016
- Engineering a novel glucose-tolerant β-glucosidase as supplementation to enhance the hydrolysis of sugarcane bagasse at high glucose concentration., Lichuang Cao, Zhijun Wang, Guang‑hui Ren, Wei Kong, Liang Li, Wei Xie and Yu‑huan Liu, 2015
- Structural basis for recognition of G-1-containing tRNA by histidyl-tRNA synthetase., Qingnan Tian, Caiyan Wang, Yuhuan Liu and Wei Xi, 2015
- Enhancing the Thermostability of Feruloyl Esterase EstF27 by Directed Evolution and the Underlying Structural Basis., Li-chuang Cao, Ran Chen, Wei Xie, and Yu-huan Liu, 2015
- Characterization of the Cross-Linked Enzyme Aggregates of a Novel β-Galactosidase, a Potential Catalyst for the Synthesis of Galacto-Oligosaccharides., Liang Li, Gang Li, Li-chuang Cao, Guang-hui Ren, Wei Kong, Si-di Wang, Geng-shan Guo, and Yu-Huan Liu, 2015
Awards
- 2016: Guangdong Province Science and Technology Progress Award, Second Prize
- 2015: Guangzhou Science and Technology Progress Award, Second Prize
- 2014: Dongguan City Science and Technology Progress Award, Third Prize