Professor | Jin'E Yang | Asia Growth Partners

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Name	Jin'E Yang
Contact Information	Issyje@mail.sysu.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Jin'E Yang

Contact Information

Issyje@mail.sysu.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Sun Yat-Sen University
Faculty	Life Sciences
Academic Background & Achievements	1993.9 – 1997.6 Bachelor in Aquaculture: Huazhong Agricultural University 1999.9 – 2004.6 PhD in Animal Genetics and Breeding: Huazhong Agricultural University
Work Experience	2004.7 – 2008.6 Lecturer - School of Life Sciences, Sun Yat-sen University 2008 – Present Associate Professor - School of Life Sciences, Sun Yat-sen University 2009.12 – 2010.11 Visiting Scholar - Medical College of Georgia (now Georgia Health Sciences University)

University/Lab Affiliation and Title

Sun Yat-Sen University

Faculty

Life Sciences

Academic Background & Achievements

1993.9 – 1997.6 Bachelor in Aquaculture: Huazhong Agricultural University
1999.9 – 2004.6 PhD in Animal Genetics and Breeding: Huazhong Agricultural University

Work Experience

2004.7 – 2008.6 Lecturer - School of Life Sciences, Sun Yat-sen University
2008 – Present Associate Professor - School of Life Sciences, Sun Yat-sen University
2009.12 – 2010.11 Visiting Scholar - Medical College of Georgia (now Georgia Health Sciences University)

Areas of Focus	Regulation of tumor-related gene expression Role and mechanism of non-coding genes in the development of liver cancer
Publications	A p53/lnc-Ip53 Negative Feedback Loop Regulates Tumor Growth and Chemoresistance, Zhang LZ#, Yang JE#, Luo YW, Liu FT, Zhuang SM, 2020 LncRNA GOLGA2P10 is induced by PERK/ATF4/CHOP signaling and protects tumor cells from ER stress-induced apoptosis by regulating Bcl-2 family members, Wu MZ, Fu T, Chen JX, Lin YY, Yang JE, Zhuang SM, 2020 Lnc-UCID promotes G1/S transition and hepatoma growth by preventing DHX9-mediated CDK6 downregulation, Wang YL#, Liu JY#, Yang JE#, Yu XM, Chen ZL, Chen YJ, Kuang M, Zhu Y, Zhuang SM, 2019 Identification of a TGF-β-miR-195 positive feedback loop in hepatocytes and its deregulation in hepatoma cells, Wang R, Fu T, You K, Li S, Zhao N, Yang J, Zhuang SM, 2018 MicroRNA-125b promotes hepatic stellate cell activation and liver fibrosis by activating RhoA signaling, You K, Li SY, Gong J, Fang JH, Zhang C, Zhang M, Yuan Y, Yang J, Zhuang SM, 2018 Vascular mimicry formation is promoted by paracrine TGF-beta and SDF1 of cancer-associated fibroblasts and inhibited by miR-101 in hepatocellular carcinoma, Yang J, Lu Y, Lin YY, Zheng ZY, Fang JH, He S, Zhuang SM, 2016 Expression of microRNA-195 is transactivated by Sp1 but inhibited by histone deacetylase 3 in hepatocellular carcinoma cells, Zhao N, Li S, Wang R, Xiao M, Meng Y, Zeng C, Fang JH, Yang J, Zhuang SM, 2016 A novel AP-1/miR-101 regulatory feedback loop and its implication in the migration and invasion of hepatoma cells, Liu JJ, Lin XJ, Yang X, Zhou L, He S, Zhuang SM, Yang J, 2014 MicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mTOR and IGF-1R, Ge YY, Shi Q, Zheng ZY, Gong J, Zeng C, Yang J, Zhuang SM, 2014 Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells, Zhou HC, Fang JH, Luo X, Zhang L, Yang J, Zhang C, Zhuang SM, 2014 Cutting Edge: IRF8 Regulates Bax Transcription In Vivo in Primary Myeloid Cells, Yang J, Hu X, Zimmerman M, Torres CM, Yang D, Smith SB, Liu K, 2011 MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression, Fang JH, Zhou HC, Zeng C, Yang J, Liu Y, Huang X, Zhang JP, et al., 2011 IRF8 regulates acid ceramidase expression to mediate apoptosis and suppresses myelogeneous leukemia, Hu X, Yang D, Zimmerman M, Liu F, Yang J, Kannan S, Burchert A, et al., 2011 Promoter polymorphism of MRP1 associated with reduced survival in hepatocellular carcinoma, Zhao J, Yu BY, Wang DY, Yang JE, 2010 Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma, Xiong Y, Fang JH, Yun JP, Yang J, Zhang Y, Jia WH, Zhuang SM, 2010 Identification of Siah-interacting protein as a potential regulator of apoptosis and curcumin resistance, Luo J, Yang J, Yu BY, Liu W, Li M, Zhuang SM, 2010 Analysis of sequence variations in 59 microRNAs in hepatocellular carcinomas, Yang J, Zhou F, Xu T, Deng H, Ge YY, Zhang C, Li J, et al., 2008 Interaction with Ppil3 leads to the cytoplasmic localization of Apoptin in tumor cells, Huo DH, Yi LN, Yang J*, 2008 Human macrophages promote the motility and invasiveness of osteopontin-knockdown tumor cells, Cheng J, Huo DH, Kuang DM, Yang J, Zheng L, Zhuang SM, 2007 BCRP gene polymorphisms are associated with susceptibility and survival of diffuse large B-cell lymphoma, Hu LL, Wang XX, Chen X, Chang J, Li C, Zhang Y, Yang J, et al., 2007

Areas of Focus

Regulation of tumor-related gene expression
Role and mechanism of non-coding genes in the development of liver cancer

Publications

A p53/lnc-Ip53 Negative Feedback Loop Regulates Tumor Growth and Chemoresistance, Zhang LZ#, Yang JE#, Luo YW, Liu FT, Zhuang SM*, 2020
LncRNA GOLGA2P10 is induced by PERK/ATF4/CHOP signaling and protects tumor cells from ER stress-induced apoptosis by regulating Bcl-2 family members, Wu MZ, Fu T, Chen JX, Lin YY, Yang JE*, Zhuang SM*, 2020
Lnc-UCID promotes G1/S transition and hepatoma growth by preventing DHX9-mediated CDK6 downregulation, Wang YL#, Liu JY#, Yang JE#, Yu XM, Chen ZL, Chen YJ, Kuang M, Zhu Y*, Zhuang SM*, 2019
Identification of a TGF-β-miR-195 positive feedback loop in hepatocytes and its deregulation in hepatoma cells, Wang R, Fu T, You K, Li S, Zhao N, Yang J*, Zhuang SM*, 2018
MicroRNA-125b promotes hepatic stellate cell activation and liver fibrosis by activating RhoA signaling, You K, Li SY, Gong J, Fang JH, Zhang C, Zhang M, Yuan Y, Yang J*, Zhuang SM*, 2018
Vascular mimicry formation is promoted by paracrine TGF-beta and SDF1 of cancer-associated fibroblasts and inhibited by miR-101 in hepatocellular carcinoma, Yang J, Lu Y, Lin YY, Zheng ZY, Fang JH, He S, Zhuang SM, 2016
Expression of microRNA-195 is transactivated by Sp1 but inhibited by histone deacetylase 3 in hepatocellular carcinoma cells, Zhao N, Li S, Wang R, Xiao M, Meng Y, Zeng C, Fang JH, Yang J*, Zhuang SM*, 2016
A novel AP-1/miR-101 regulatory feedback loop and its implication in the migration and invasion of hepatoma cells, Liu JJ, Lin XJ, Yang X, Zhou L, He S, Zhuang SM*, Yang J*, 2014
MicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mTOR and IGF-1R, Ge YY, Shi Q, Zheng ZY, Gong J, Zeng C, Yang J, Zhuang SM*, 2014
Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells, Zhou HC, Fang JH, Luo X, Zhang L, Yang J, Zhang C, Zhuang SM*, 2014
Cutting Edge: IRF8 Regulates Bax Transcription In Vivo in Primary Myeloid Cells, Yang J, Hu X, Zimmerman M, Torres CM, Yang D, Smith SB, Liu K, 2011
MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression, Fang JH, Zhou HC, Zeng C, Yang J, Liu Y, Huang X, Zhang JP, et al., 2011
IRF8 regulates acid ceramidase expression to mediate apoptosis and suppresses myelogeneous leukemia, Hu X, Yang D, Zimmerman M, Liu F, Yang J, Kannan S, Burchert A, et al., 2011
Promoter polymorphism of MRP1 associated with reduced survival in hepatocellular carcinoma, Zhao J, Yu BY, Wang DY, Yang JE*, 2010
Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma, Xiong Y, Fang JH, Yun JP, Yang J, Zhang Y, Jia WH, Zhuang SM, 2010
Identification of Siah-interacting protein as a potential regulator of apoptosis and curcumin resistance, Luo J, Yang J, Yu BY, Liu W, Li M, Zhuang SM, 2010
Analysis of sequence variations in 59 microRNAs in hepatocellular carcinomas, Yang J, Zhou F, Xu T, Deng H, Ge YY, Zhang C, Li J, et al., 2008
Interaction with Ppil3 leads to the cytoplasmic localization of Apoptin in tumor cells, Huo DH, Yi LN, Yang J*, 2008
Human macrophages promote the motility and invasiveness of osteopontin-knockdown tumor cells, Cheng J, Huo DH, Kuang DM, Yang J, Zheng L, Zhuang SM, 2007
BCRP gene polymorphisms are associated with susceptibility and survival of diffuse large B-cell lymphoma, Hu LL, Wang XX, Chen X, Chang J, Li C, Zhang Y, Yang J, et al., 2007

Tumor Gene Expression Regulation Non-Coding Genes Liver Cancer Development Mechanism Oncology Biochemistry Molecular Biology

Lu Dongdong - Tongji University

Shi Jiejun - Tongji University

Yixuan Wang - Tongji University

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