Professor | 杨金娥 | 数字化转型顾问

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Name	杨金娥
Contact Information	Issyje@mail.sysu.edu.cn
Language ability	中文, 英文
Province	广东

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Name

杨金娥

Contact Information

Issyje@mail.sysu.edu.cn

Language ability

中文, 英文

Province

广东

University/Lab Affiliation and Title	中山大学
Faculty	Life Sciences
Academic Background & Achievements	1993.9 – 1997.6 水产养殖学士: 华中农业大学 1999.9 – 2004.6 动物遗传育种博士: 华中农业大学
Work Experience	2004.7 – 2008.6 讲师 - 中山大学生命科学学院 2008 – 至今副教授 - 中山大学生命科学学院 2009.12 – 2010.11 访问学者 - 美国乔治亚医学院（现乔治亚健康科学大学）

University/Lab Affiliation and Title

中山大学

Faculty

Life Sciences

Academic Background & Achievements

1993.9 – 1997.6 水产养殖学士: 华中农业大学
1999.9 – 2004.6 动物遗传育种博士: 华中农业大学

Work Experience

2004.7 – 2008.6 讲师 - 中山大学生命科学学院
2008 – 至今副教授 - 中山大学生命科学学院
2009.12 – 2010.11 访问学者 - 美国乔治亚医学院（现乔治亚健康科学大学）

Areas of Focus	肿瘤相关基因的表达调控非编码基因在肝癌发生发展中的作用及机制
Publications	A p53/lnc-Ip53 Negative Feedback Loop Regulates Tumor Growth and Chemoresistance, Zhang LZ#, Yang JE#, Luo YW, Liu FT, Zhuang SM, 2020 LncRNA GOLGA2P10 is induced by PERK/ATF4/CHOP signaling and protects tumor cells from ER stress-induced apoptosis by regulating Bcl-2 family members, Wu MZ, Fu T, Chen JX, Lin YY, Yang JE, Zhuang SM, 2020 Lnc-UCID promotes G1/S transition and hepatoma growth by preventing DHX9-mediated CDK6 downregulation, Wang YL#, Liu JY#, Yang JE#, Yu XM, Chen ZL, Chen YJ, Kuang M, Zhu Y, Zhuang SM, 2019 Identification of a TGF-β-miR-195 positive feedback loop in hepatocytes and its deregulation in hepatoma cells, Wang R, Fu T, You K, Li S, Zhao N, Yang J, Zhuang SM, 2018 MicroRNA-125b promotes hepatic stellate cell activation and liver fibrosis by activating RhoA signaling, You K, Li SY, Gong J, Fang JH, Zhang C, Zhang M, Yuan Y, Yang J, Zhuang SM, 2018 Vascular mimicry formation is promoted by paracrine TGF-beta and SDF1 of cancer-associated fibroblasts and inhibited by miR-101 in hepatocellular carcinoma, Yang J, Lu Y, Lin YY, Zheng ZY, Fang JH, He S, Zhuang SM, 2016 Expression of microRNA-195 is transactivated by Sp1 but inhibited by histone deacetylase 3 in hepatocellular carcinoma cells, Zhao N, Li S, Wang R, Xiao M, Meng Y, Zeng C, Fang JH, Yang J, Zhuang SM, 2016 A novel AP-1/miR-101 regulatory feedback loop and its implication in the migration and invasion of hepatoma cells, Liu JJ, Lin XJ, Yang X, Zhou L, He S, Zhuang SM, Yang J, 2014 MicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mTOR and IGF-1R, Ge YY, Shi Q, Zheng ZY, Gong J, Zeng C, Yang J, Zhuang SM, 2014 Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells, Zhou HC, Fang JH, Luo X, Zhang L, Yang J, Zhang C, Zhuang SM, 2014 Cutting Edge: IRF8 Regulates Bax Transcription In Vivo in Primary Myeloid Cells, Yang J, Hu X, Zimmerman M, Torres CM, Yang D, Smith SB, Liu K, 2011 MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression, Fang JH, Zhou HC, Zeng C, Yang J, Liu Y, Huang X, Zhang JP, et al., 2011 IRF8 regulates acid ceramidase expression to mediate apoptosis and suppresses myelogeneous leukemia, Hu X, Yang D, Zimmerman M, Liu F, Yang J, Kannan S, Burchert A, et al., 2011 Promoter polymorphism of MRP1 associated with reduced survival in hepatocellular carcinoma, Zhao J, Yu BY, Wang DY, Yang JE, 2010 Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma, Xiong Y, Fang JH, Yun JP, Yang J, Zhang Y, Jia WH, Zhuang SM, 2010 Identification of Siah-interacting protein as a potential regulator of apoptosis and curcumin resistance, Luo J, Yang J, Yu BY, Liu W, Li M, Zhuang SM, 2010 Analysis of sequence variations in 59 microRNAs in hepatocellular carcinomas, Yang J, Zhou F, Xu T, Deng H, Ge YY, Zhang C, Li J, et al., 2008 Interaction with Ppil3 leads to the cytoplasmic localization of Apoptin in tumor cells, Huo DH, Yi LN, Yang J*, 2008 Human macrophages promote the motility and invasiveness of osteopontin-knockdown tumor cells, Cheng J, Huo DH, Kuang DM, Yang J, Zheng L, Zhuang SM, 2007 BCRP gene polymorphisms are associated with susceptibility and survival of diffuse large B-cell lymphoma, Hu LL, Wang XX, Chen X, Chang J, Li C, Zhang Y, Yang J, et al., 2007

Areas of Focus

肿瘤相关基因的表达调控
非编码基因在肝癌发生发展中的作用及机制

Publications

A p53/lnc-Ip53 Negative Feedback Loop Regulates Tumor Growth and Chemoresistance, Zhang LZ#, Yang JE#, Luo YW, Liu FT, Zhuang SM*, 2020
LncRNA GOLGA2P10 is induced by PERK/ATF4/CHOP signaling and protects tumor cells from ER stress-induced apoptosis by regulating Bcl-2 family members, Wu MZ, Fu T, Chen JX, Lin YY, Yang JE*, Zhuang SM*, 2020
Lnc-UCID promotes G1/S transition and hepatoma growth by preventing DHX9-mediated CDK6 downregulation, Wang YL#, Liu JY#, Yang JE#, Yu XM, Chen ZL, Chen YJ, Kuang M, Zhu Y*, Zhuang SM*, 2019
Identification of a TGF-β-miR-195 positive feedback loop in hepatocytes and its deregulation in hepatoma cells, Wang R, Fu T, You K, Li S, Zhao N, Yang J*, Zhuang SM*, 2018
MicroRNA-125b promotes hepatic stellate cell activation and liver fibrosis by activating RhoA signaling, You K, Li SY, Gong J, Fang JH, Zhang C, Zhang M, Yuan Y, Yang J*, Zhuang SM*, 2018
Vascular mimicry formation is promoted by paracrine TGF-beta and SDF1 of cancer-associated fibroblasts and inhibited by miR-101 in hepatocellular carcinoma, Yang J, Lu Y, Lin YY, Zheng ZY, Fang JH, He S, Zhuang SM, 2016
Expression of microRNA-195 is transactivated by Sp1 but inhibited by histone deacetylase 3 in hepatocellular carcinoma cells, Zhao N, Li S, Wang R, Xiao M, Meng Y, Zeng C, Fang JH, Yang J*, Zhuang SM*, 2016
A novel AP-1/miR-101 regulatory feedback loop and its implication in the migration and invasion of hepatoma cells, Liu JJ, Lin XJ, Yang X, Zhou L, He S, Zhuang SM*, Yang J*, 2014
MicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mTOR and IGF-1R, Ge YY, Shi Q, Zheng ZY, Gong J, Zeng C, Yang J, Zhuang SM*, 2014
Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells, Zhou HC, Fang JH, Luo X, Zhang L, Yang J, Zhang C, Zhuang SM*, 2014
Cutting Edge: IRF8 Regulates Bax Transcription In Vivo in Primary Myeloid Cells, Yang J, Hu X, Zimmerman M, Torres CM, Yang D, Smith SB, Liu K, 2011
MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression, Fang JH, Zhou HC, Zeng C, Yang J, Liu Y, Huang X, Zhang JP, et al., 2011
IRF8 regulates acid ceramidase expression to mediate apoptosis and suppresses myelogeneous leukemia, Hu X, Yang D, Zimmerman M, Liu F, Yang J, Kannan S, Burchert A, et al., 2011
Promoter polymorphism of MRP1 associated with reduced survival in hepatocellular carcinoma, Zhao J, Yu BY, Wang DY, Yang JE*, 2010
Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma, Xiong Y, Fang JH, Yun JP, Yang J, Zhang Y, Jia WH, Zhuang SM, 2010
Identification of Siah-interacting protein as a potential regulator of apoptosis and curcumin resistance, Luo J, Yang J, Yu BY, Liu W, Li M, Zhuang SM, 2010
Analysis of sequence variations in 59 microRNAs in hepatocellular carcinomas, Yang J, Zhou F, Xu T, Deng H, Ge YY, Zhang C, Li J, et al., 2008
Interaction with Ppil3 leads to the cytoplasmic localization of Apoptin in tumor cells, Huo DH, Yi LN, Yang J*, 2008
Human macrophages promote the motility and invasiveness of osteopontin-knockdown tumor cells, Cheng J, Huo DH, Kuang DM, Yang J, Zheng L, Zhuang SM, 2007
BCRP gene polymorphisms are associated with susceptibility and survival of diffuse large B-cell lymphoma, Hu LL, Wang XX, Chen X, Chang J, Li C, Zhang Y, Yang J, et al., 2007

肿瘤基因表达调控非编码基因肝癌发展机制肿瘤学生物化学分子生物学

陆东东 - 同济大学

史偈君 - 同济大学

Area of Focus
表观遗传学 | 多态性 | 基因表达 | 调控 | 发展 | 衰老 | 肿瘤异质性 | 诊断 | 治疗 | 多组学

王译萱 - 同济大学

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