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杨金娥
Life Science
中山大学
广东
Language: 中文, 英文
肿瘤
基因表达
调控
非编码基因
肝癌
发展
机制
肿瘤学
生物化学
分子生物学
Areas of Focus
- 肿瘤相关基因的表达调控
- 非编码基因在肝癌发生发展中的作用及机制
Work Experience
- 2004.7 – 2008.6 讲师 - 中山大学生命科学学院
- 2008 – 至今 副教授 - 中山大学生命科学学院
- 2009.12 – 2010.11 访问学者 - 美国乔治亚医学院（现乔治亚健康科学大学）
Academic Background & Achievements
- 1993.9 – 1997.6 水产养殖学士: 华中农业大学
- 1999.9 – 2004.6 动物遗传育种博士: 华中农业大学
Publications
- A p53/lnc-Ip53 Negative Feedback Loop Regulates Tumor Growth and Chemoresistance, Zhang LZ#, Yang JE#, Luo YW, Liu FT, Zhuang SM*, 2020
- LncRNA GOLGA2P10 is induced by PERK/ATF4/CHOP signaling and protects tumor cells from ER stress-induced apoptosis by regulating Bcl-2 family members, Wu MZ, Fu T, Chen JX, Lin YY, Yang JE*, Zhuang SM*, 2020
- Lnc-UCID promotes G1/S transition and hepatoma growth by preventing DHX9-mediated CDK6 downregulation, Wang YL#, Liu JY#, Yang JE#, Yu XM, Chen ZL, Chen YJ, Kuang M, Zhu Y*, Zhuang SM*, 2019
- Identification of a TGF-β-miR-195 positive feedback loop in hepatocytes and its deregulation in hepatoma cells, Wang R, Fu T, You K, Li S, Zhao N, Yang J*, Zhuang SM*, 2018
- MicroRNA-125b promotes hepatic stellate cell activation and liver fibrosis by activating RhoA signaling, You K, Li SY, Gong J, Fang JH, Zhang C, Zhang M, Yuan Y, Yang J*, Zhuang SM*, 2018
- Vascular mimicry formation is promoted by paracrine TGF-beta and SDF1 of cancer-associated fibroblasts and inhibited by miR-101 in hepatocellular carcinoma, Yang J, Lu Y, Lin YY, Zheng ZY, Fang JH, He S, Zhuang SM, 2016
- Expression of microRNA-195 is transactivated by Sp1 but inhibited by histone deacetylase 3 in hepatocellular carcinoma cells, Zhao N, Li S, Wang R, Xiao M, Meng Y, Zeng C, Fang JH, Yang J*, Zhuang SM*, 2016
- A novel AP-1/miR-101 regulatory feedback loop and its implication in the migration and invasion of hepatoma cells, Liu JJ, Lin XJ, Yang X, Zhou L, He S, Zhuang SM*, Yang J*, 2014
- MicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mTOR and IGF-1R, Ge YY, Shi Q, Zheng ZY, Gong J, Zeng C, Yang J, Zhuang SM*, 2014
- Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells, Zhou HC, Fang JH, Luo X, Zhang L, Yang J, Zhang C, Zhuang SM*, 2014
- Cutting Edge: IRF8 Regulates Bax Transcription In Vivo in Primary Myeloid Cells, Yang J, Hu X, Zimmerman M, Torres CM, Yang D, Smith SB, Liu K, 2011
- MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression, Fang JH, Zhou HC, Zeng C, Yang J, Liu Y, Huang X, Zhang JP, et al., 2011
- IRF8 regulates acid ceramidase expression to mediate apoptosis and suppresses myelogeneous leukemia, Hu X, Yang D, Zimmerman M, Liu F, Yang J, Kannan S, Burchert A, et al., 2011
- Promoter polymorphism of MRP1 associated with reduced survival in hepatocellular carcinoma, Zhao J, Yu BY, Wang DY, Yang JE*, 2010
- Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma, Xiong Y, Fang JH, Yun JP, Yang J, Zhang Y, Jia WH, Zhuang SM, 2010
- Identification of Siah-interacting protein as a potential regulator of apoptosis and curcumin resistance, Luo J, Yang J, Yu BY, Liu W, Li M, Zhuang SM, 2010
- Analysis of sequence variations in 59 microRNAs in hepatocellular carcinomas, Yang J, Zhou F, Xu T, Deng H, Ge YY, Zhang C, Li J, et al., 2008
- Interaction with Ppil3 leads to the cytoplasmic localization of Apoptin in tumor cells, Huo DH, Yi LN, Yang J*, 2008
- Human macrophages promote the motility and invasiveness of osteopontin-knockdown tumor cells, Cheng J, Huo DH, Kuang DM, Yang J, Zheng L, Zhuang SM, 2007
- BCRP gene polymorphisms are associated with susceptibility and survival of diffuse large B-cell lymphoma, Hu LL, Wang XX, Chen X, Chang J, Li C, Zhang Y, Yang J, et al., 2007
