Professor | Huabing Li | Asia Growth Partners

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Name	Huabing Li
Contact Information	huabing.li@yale.edu
Language ability	English, Chinese
Province	Chongqing

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Name

Huabing Li

Contact Information

huabing.li@yale.edu

Language ability

English, Chinese

Province

Chongqing

University/Lab Affiliation and Title	Chongqing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2012-2017: Postdoctoral Researcher at Yale University 2011-2012: Postdoctoral Researcher at Rutgers University 2005-2011: Ph.D. from Rutgers University 2002-2005: M.S. from Nankai University 1999-2002: B.S. from Nankai University
Work Experience	2024-present: Professor at Chongqing Medical University 2022.3-present: Distinguished Professor at Ruijin Hospital, Shanghai Jiao Tong University School of Medicine 2020.5-present: Principal Investigator at State Key Laboratory of Oncogenes and Related Genes 2019.5-present: Researcher at Shanghai Jiao Tong University School of Medicine-Yale University Institute of Immunometabolism 2017.8-present: Senior Researcher at Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine; Adjunct Assistant Professor at Yale University School of Medicine
Awards	2023: National Science Fund for Distinguished Young Scholars 2022: Shanghai Health and Family Planning Commission Academic Leader 2018: National High-level Overseas Talent Youth Project 2018: Shanghai 'Oriental Scholar' Distinguished Professor

University/Lab Affiliation and Title

Chongqing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2012-2017: Postdoctoral Researcher at Yale University
2011-2012: Postdoctoral Researcher at Rutgers University
2005-2011: Ph.D. from Rutgers University
2002-2005: M.S. from Nankai University
1999-2002: B.S. from Nankai University

Work Experience

2024-present: Professor at Chongqing Medical University
2022.3-present: Distinguished Professor at Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
2020.5-present: Principal Investigator at State Key Laboratory of Oncogenes and Related Genes
2019.5-present: Researcher at Shanghai Jiao Tong University School of Medicine-Yale University Institute of Immunometabolism
2017.8-present: Senior Researcher at Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine; Adjunct Assistant Professor at Yale University School of Medicine

Awards

2023: National Science Fund for Distinguished Young Scholars
2022: Shanghai Health and Family Planning Commission Academic Leader
2018: National High-level Overseas Talent Youth Project
2018: Shanghai 'Oriental Scholar' Distinguished Professor

Areas of Focus	RNA Modifications and Epigenetic Immunity
Publications	A Treg specific long non-coding RNA maintains immune-metabolic homeostasis in ageing liver., Ding C#, Yu Z#, Sefik E#, Zhou J#, Kaffe E, Wang G, Li B, Flavell RA, Hu W, Ye Y, Li HB., 2023 tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis., Liu Y#, Zhou J#, Li X#, Zhang X#, Shi J#, Wang X, Li H, Miao S, Chen H, He X, Dong L, Lee GR, Zhen J, Liu RJ, Su B, Ye Y, Flavell RA, Yi C, Wu Y, Li HB., 2022 RNA m6A demethylase ALKBH5 regulates the development of γδ T cells., Ding C#, Xu H#, Yu Z#, Roulis M, Qu R, Zhou J, Oh J, Crawford J, Gao Y, Jackson R, Sefik E, Li S, Wei Z, Skadow M, Yin Z, Ouyang X, Wang L, Zou Q, Su B, Hu W, Flavell R, Li HB., 2022 DENR controls JAK2 translation to induce PD-L1 expression for tumor immune evasion., Chen B#, Hu J#, Chen H, Bao R, Zhou Y, Zhan M, Ye Y, Li H, Li HB., 2022 m6A mRNA modification maintains colonic epithelial cell homeostasis via NF-κb-mediated anti-apoptotic pathway., Zhang T#, Ding C#, Chen H# Zhao J, Chen J, Chen B, Mao K, Hao Y, Roulis M, Xu H, Kluger Y, Zou Q, Ye Y, Zhan M, Flavell RA, Li HB., 2022 m6A Demethylase ALKBH5 Controls CD4+ T cell Pathogenicity and Promotes Autoimmunity., Zhou J#, Zhang X#, Hu J, Qu R, Yu Z, Xu H, Chen H, Yan L, Ding C, Zou Q, Ye Y, Wang Z, Flavell RA, Li HB., 2021 Pooled CRISPR Screening Identifies m6A as a Positive Regulator of Macrophage Activation., Tong J#, Wang X#, Liu Y#, Ren X, Wang A, Chen Z, Yao J, Mao K, Liu T, Meng FL, Pan W, Zou Q, Zhou Y, Xia Q, Flavell RA, Zhu S, Li HB., 2021 Cross-talk of Four Types of RNA Modification Writers Defines Tumor Microenvironment and Pharmacogenomic Landscape in Colorectal Cancer., Chen H#, Yao J#, Bao R, Dong Y, Zhang T, Du Y, Wang G, Ni D, Xun Z, Niu X, Ye Y, Li HB., 2021 m6A mRNA methylation sustains Treg suppressive functions., Tong J#, Cao G#, Zhang T#, Sefik E, Vesely M, Broughton J, Zhu S, Li H, Li B, Chen L, Chang HY, Su B, Flavell RA, Li HB., 2018 m6A mRNA methylation controls T cell homeostasis by targeting IL-7/STAT5/SOCS pathway., Li HB#, Tong J#, Zhu S#, Batista PJ, Duffy EE, Zhao J, Bailis W, Cao G, Kroehling L, Chen Y, Wang G, Broughton JP, Chen YG, Kluger Y, Simon MD, Chang HY, Yin Z, Flavell RA*., 2017

Areas of Focus

RNA Modifications and Epigenetic Immunity

Publications

A Treg specific long non-coding RNA maintains immune-metabolic homeostasis in ageing liver., Ding C#, Yu Z#, Sefik E#, Zhou J#, Kaffe E, Wang G, Li B, Flavell RA, Hu W, Ye Y, Li HB*., 2023
tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis., Liu Y#, Zhou J#, Li X#, Zhang X#, Shi J#, Wang X, Li H, Miao S, Chen H, He X, Dong L, Lee GR, Zhen J, Liu RJ, Su B, Ye Y, Flavell RA*, Yi C*, Wu Y*, Li HB*., 2022
RNA m6A demethylase ALKBH5 regulates the development of γδ T cells., Ding C#, Xu H#, Yu Z#, Roulis M, Qu R, Zhou J, Oh J, Crawford J, Gao Y, Jackson R, Sefik E, Li S, Wei Z, Skadow M, Yin Z, Ouyang X, Wang L, Zou Q, Su B, Hu W*, Flavell R*, Li HB*., 2022
DENR controls JAK2 translation to induce PD-L1 expression for tumor immune evasion., Chen B#, Hu J#, Chen H, Bao R, Zhou Y, Zhan M*, Ye Y*, Li H*, Li HB*., 2022
m6A mRNA modification maintains colonic epithelial cell homeostasis via NF-κb-mediated anti-apoptotic pathway., Zhang T#, Ding C#*, Chen H# Zhao J, Chen J, Chen B, Mao K, Hao Y, Roulis M, Xu H, Kluger Y, Zou Q, Ye Y, Zhan M*, Flavell RA*, Li HB*., 2022
m6A Demethylase ALKBH5 Controls CD4+ T cell Pathogenicity and Promotes Autoimmunity., Zhou J#, Zhang X#, Hu J, Qu R, Yu Z, Xu H, Chen H, Yan L, Ding C, Zou Q, Ye Y, Wang Z, Flavell RA*, Li HB*., 2021
Pooled CRISPR Screening Identifies m6A as a Positive Regulator of Macrophage Activation., Tong J#, Wang X#, Liu Y#, Ren X, Wang A, Chen Z, Yao J, Mao K, Liu T, Meng FL, Pan W, Zou Q, Zhou Y, Xia Q*, Flavell RA*, Zhu S*, Li HB*., 2021
Cross-talk of Four Types of RNA Modification Writers Defines Tumor Microenvironment and Pharmacogenomic Landscape in Colorectal Cancer., Chen H#, Yao J#, Bao R, Dong Y, Zhang T, Du Y, Wang G, Ni D, Xun Z, Niu X, Ye Y*, Li HB*., 2021
m6A mRNA methylation sustains Treg suppressive functions., Tong J#, Cao G#, Zhang T#, Sefik E, Vesely M, Broughton J, Zhu S, Li H, Li B, Chen L, Chang HY, Su B, Flavell RA*, Li HB*., 2018
m6A mRNA methylation controls T cell homeostasis by targeting IL-7/STAT5/SOCS pathway., Li HB#*, Tong J#, Zhu S#, Batista PJ, Duffy EE, Zhao J, Bailis W, Cao G, Kroehling L, Chen Y, Wang G, Broughton JP, Chen YG, Kluger Y, Simon MD, Chang HY, Yin Z*, Flavell RA*., 2017

Rna Modifications Epigenetics Immunity Immune Cells Molecular Mechanisms Physiological Pathological Regulation Function

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